Introduction About AZAFAB 100MG INJECTION
AZAFAB 100MG INJECTION is used in adults in the management of all sub-types of myelodysplastic syndromes (MDS, a group of cancers associated with blood and bone marrow), and certain types of blood cancer known as chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).
It contains a medicine called Azacitidine, which belongs to the group of medicines called Anticancer agents. It works by blocking certain enzymes that affect DNA in cancer cells, which helps stop their growth and encourages them to die.
CMML is a type of blood cancer where the bone marrow releases an excess amount of monocytes (a type of blood cell) into the blood stream, whereas in AML, the bone marrow releases an excess amount of immature white blood cells. Both are characterized by recurrent infections, fever, tiredness, and increased bleeding or bruising.
AZAFAB 100MG INJECTION is typically used in adults who cannot undergo stem cell transplantation. Before receiving this medicine, inform your doctor if you have any lung, liver, kidney, or heart problems.
AZAFAB 100MG INJECTION is not recommended for use by pregnant or breastfeeding women. Both men and women of childbearing potential must use a suitable contraceptive to avoid pregnancy while undergoing therapy with this medicine. Men may seek advice on sperm preservation, if necessary, prior to therapy with this medicine.
The most common side effects of receiving AZAFAB 100MG INJECTION are increased bleeding, increased infections, tiredness, nausea, vomiting, diarrhea, constipation, loss of appetite, stomach pain, weakness, pain and redness at the site of injection, sore nose and throat, cold sores, headache, dizziness, trouble sleeping, weight loss, ulcers of the mouth or tongue, and hair loss. Consult your doctor if any of these side effects trouble you.
Uses Of AZAFAB 100MG INJECTION
It is used by adults to manage:
- all sub-types of myelodysplastic syndromes (MDS; a group of cancers associated with blood and bone marrow)
- Chronic myelomonocytic leukemia (CMML; blood cancer of monocytes)
- acute myeloid leukemia (AML; blood cancer of the WBC)
How AZAFAB 100MG INJECTION Works
AZAFAB 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that are required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it manages abnormal cell division within the body, slows down the growth of cancer cells, and helps the bone marrow produce normal blood cells.
How to use AZAFAB 100MG INJECTION
- This medicine will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of your thighs, arms, or abdomen.
- Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.
Side Effects Of AZAFAB 100MG INJECTION
COMMON
- low RBC count, causing anemia, tiredness, and pale skin
- increased infections, lung infections (pneumonia), fever, and chills
- increased bleeding tendency due to low blood platelet counts
- nausea, vomiting
- diarrhea, constipation, loss of appetite, and stomach pain
- tiredness, weakness
- injection site reactions (such as pain, redness, swelling, or lump formation)
- Joint pain, muscle pain, and skin rashes with redness and itching
- sore nose and throat, cold sores, sinusitis
- headache, dizziness
- trouble sleeping (insomnia)
- Nosebleeds, bleeding gums
- weight loss
- urinary tract infections
- ulcers of the mouth or tongue
- high or low blood pressure
- anxiety, confusion
- hair loss, dehydration
- oral fungal infection
- sleepiness
- fluid around the lungs or heart
Consult your doctor immediately if you experience any of the following side effects after receiving AZAFAB 100MG INJECTION:
- signs of liver problems (such as yellowing of the skin and whites of the eye, drowsiness, shakiness, bloating, and easy bruising)
- signs of kidney problems (such as low urine output, swollen feet and legs, back pain, rapid heart rate, dizziness, nausea, vomiting, tiredness, reduced appetite, confusion, and restlessness)
- signs of increased infections, such as fever
| Weight | 110 g |
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