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Flavedon MR 35mg Tablet 10’S
Original price was: ₹174.23.₹165.65Current price is: ₹165.65.
*10 Tablet(s) in a Strip
* Mkt: Servier India PVT LTD (Formerly Known As Serdia Pharmaceuticals (India) Pvt Ltd) * Country of Origin: India
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Introduction About FLAVEDON MR 35MG TABLET
What is Flavedon MR 35mg?
Flavedon
MR 35mg is a medication used to manage stable angina and improve heart
function. It contains Trimetazidine which helps to maintain energy
metabolism in heart cells.
Flavedon Tablet helps to reduce chest
pain (angina), improves heart function in ischemic conditions and helps
in maintaining energy metabolism.
Take Flavedon MR 35mg as prescribed by your doctor. It is usually taken twice daily with meals.
Flavedon MR 35mg is not recommended for use if you have Parkinson disease or severe kidney problems.
This
medicine should be used cautiously in elderly patients (above 75
years), pregnant, and breast-feeding mothers. Do not drive or operate
any machinery if you feel dizzy after taking Flavedon MR 35mg.
The
common side effects associated with Flavedon MR 35mg are dizziness,
nausea, stomach pain. Consult your doctor if the any of the above side
effects persists for a longer duration.
Key Composition
The active ingredient in Flavedon MR 35mg Tablet:
- Trimetazidine
Dihydrochloride (35mg) – used for the management of Angina pectoris
(chest pain due to reduced blood flow to the heart)
Uses Of FLAVEDON MR 35MG TABLET
- Used to manage Angina and improve heart health
Benefits of FLAVEDON MR 35MG TABLET
1. Reduce chest pain (Angina):
- Flavedon MR 35mg helps in reducing the frequency and severity of angina attacks
- It
does this by optimizing heart cell metabolism, ensuring better oxygen
utilization without increasing heart rate or blood pressure
2. Improves heart function in ischemic conditions:
- In
conditions like Ischemic heart disease (IHD), where blood supply to the
heart is reduced, Flavedon MR helps to protect heart muscles from
damage - It enhances cellular energy production, reducing further heart complications
3. Helps in maintaining energy metabolism:
- Flavedon
MR works at the mitochondrial level to maintain normal energy
production, especially in stressed heart and muscle tissues - This helps in reducing fatigue, muscle weakness, and improving exercise tolerance in patients with heart conditions
How FLAVEDON MR 35MG TABLET Works
1. Shifts energy production from fatty acid oxidation to glucose oxidation:
- Trimetazidine selectively inhibits an enzyme called 3-ketoacyl-CoA thiolase (3-KAT) in fatty acid metabolism
- This
reduces fatty acid oxidation and enhances glucose oxidation, which is
more oxygen-efficient and beneficial for ischemic tissues
2. Maintains ATP (Energy) levels in heart cells:
- By
optimizing glucose oxidation, Flavedon MR helps heart cells produce
more ATP, ensuring better cell function under ischemic stress
3. Reduces calcium overload & cell decay
- Ischemia can cause calcium accumulation in heart cells, leading to mitochondrial damage and cell decay
- Flavedon MR stabilizes calcium balance, reducing oxidative stress and cell injury
How to use FLAVEDON MR 35MG TABLET
Flavedon
MR is a prescription medicine which needs to be taken under medical
supervision. Always consult your doctor or pharmacist if you have any
questions or concerns about taking this medication.
Recommended dosage for Flavedon MR:
- Dosage: 35 mg twice daily (morning and evening) with meals
Can I take Flavedon MR on an empty stomach?
- Flavedon MR should be taken with food to enhance absorption and reduce stomach discomfort
Method of administration for Flavedon MR:
- Take Flavedon MR 35mg as prescribed by your doctor
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition
What if I forgot to take FLAVEDON MR 35MG TABLET
Missed a Dose? Here’s what to do:
- Take it as soon as you remember if it is not too close to the next dose
- Do not double dose to make up for a missed one
- Skip the missed dose and continue with your regular dosing schedule
- Try to take it at the same time every day to maintain stable levels in your body
Overdose
Seek emergency medical attention if:
- you experience severe drowsiness, tremors, or loss of consciousness
- irregular heartbeat or breathing difficulty
- symptoms worsen over time instead of improving
Side Effects Of FLAVEDON MR 35MG TABLET
Common side effects include:
- dizziness
- nausea
- stomach pain
When to consult a doctor?
- signs of low blood pressure such as dizziness, light headiness or fainting, malaise (feeling of being unwell), and fall flushing
- signs
of low platelet count (thrombocytopenia) such as frequent bruising,
superficial bleeding, and prolonged bleeding from wounds - low white blood cell count that increases vulnerability to infections
How To Manage Side Effects
Dizziness Or Drowsiness
- When getting up from a sitting or lying position, do it slowly to reduce sudden drop in blood pressure
- Drink plenty of water throughout the day to maintain blood circulation
- Eat regular meals and include proteins complex carbs to maintain energy levels
Nausea And Vomiting
- Avoid taking medicine on an empty stomach, as it may worsen nausea
- Avoid taking fried, oily, or heavily spiced foods which can aggravate nausea
- Do not lie down immediately after meals, as this may worsen nausea and acid reflux
Stomach Pain
- Wait at least 30 minutes after taking Flavedon MR before lying down to reduce acid reflux or irritation
- Avoid carbonated, acidic, or caffeinated drinks that can increase stomach acidity
- Ginger tea, chamomile tea, or peppermint tea can help soothe stomach discomfort
Warning & Precautions
Pregnancy
Consult your doctor
There
are no well-controlled clinical trials in pregnant women. Animal
studies do not show direct teratogenic effects, but due to insufficient
human data, its safety remains unclear. Doctors generally avoid
prescribing Flavedon MR 35mg to pregnant women unless the potential
benefit outweighs the risk.
Breastfeeding
Consult your doctor
There
are no human studies confirming whether Trimetazidine passes into
breast milk. Given the lack of safety data, it is better to avoid
Flavedon MR 35mg while breastfeeding to reduce the potential risks to
the baby. If the management is essential, consider switching to formula
feeding under medical supervision.
Driving and Using Machines
Use with Caution
Do not drive or operate any machinery if you feel dizzy after taking Flavedon MR 35mg.
Alcohol
Consult your doctor
Avoid consumption of alcohol while taking Flavedon MR 35mg because it may make you dizzier.
Kidney
Contraindicated
Flavedon
MR 35mg is not recommended for use if you are having kidney-related
problems. Consult your doctor before taking the medicine.
Allergy
Contraindicated
Do
not take Flavedon MR 35mg if you are allergic to Trimetazidine or any
other ingredient in this medicine. Consult your doctor before taking the
medicine.
Heart Disease
Consult your doctor
Flavedon
MR 35mg Tablet should be used with caution in patients with heart
diseases. This medicine does not manage sudden angina attacks and should
not be used as a management for unstable or heart attacks. Consult your
doctor before taking the medicine.
Use In Pediatrics
Contraindicated
Is Flavedon MR Safe for children?
Flavedon MR is not approved for use in children and adolescents under 18 due to a lack of clinical safety data.
Why?
- The effects of trimetazidine on a developing heart and metabolism are not well studied
- Children with heart conditions should follow alternative managements prescribed by a pediatric cardiologist
Use In Geriatrics
Use with Caution
Flavedon MR 35mg should be used with caution in elderly patients (above 75 years).
Who should not take [GBNKEYWORD
Flavedon MR 35mg Tablet is not recommended for use if you:
- have Parkinson disease
Safety Advice
- Take Flavedon MR exactly as prescribed usually one tablet twice daily with food
- It
is not recommended for patients with Parkinson’s disease, severe kidney
disease patients and during pregnancy & breastfeeding - Flavedon MR 35mg is not recommended for children and adolescents (under 18 years)
- Be cautious with blood pressure medications and avoid consumption of alcohol as it may cause dizziness
- Be cautious while driving and avoid using heavy machines
- Keep in a cool, dry place away from sunlight and Store out of reach of children
Diet and Lifestyle Advice
What to avoid while taking Flavedon MR?
Lifestyle habits to Avoid:
- Skipping doses or stopping suddenly
- Smoking & alcohol
- Strenuous physical activity
- Dehydration
Foods & drinks to avoid:
- Excessive caffeine (coffee, tea, energy drinks)
- High-sodium & processed foods
- Grapefruit & grapefruit juice
- High-sugar foods
Heart-healthy diet tips for patients taking Flavedon MR:
1. Eat more heart-friendly foods
- Leafy greens (spinach, kale, broccoli)
- Fatty fish (salmon, mackerel, sardines)
- Whole grains (brown rice, oats, quinoa, whole wheat bread)
- Nuts & seeds (almonds, walnuts, chia, flaxseeds)
- Fruits (berries, apples, citrus, pomegranates)
- Legumes & beans (lentils, chickpeas, kidney beans)
2. Stay hydrated & choose heart-smart drinks
- Water
- Herbal teas (green tea, hibiscus, ginger tea)
- Fresh homemade juices (without added sugar) – pomegranate, orange, or beetroot juice
3. Portion control & eating habits
- Eat smaller, balanced meals – overeating can strain the heart and cause blood sugar spikes
- Avoid late-night eating – late meals can increase heartburn and interfere with sleep
- Chew slowly & eat mindfully – helps digestion and reduces overeating
Best exercises for Heart patients on medication:
- Walking: Start with 15-20 minutes/day, gradually increasing to 30-45 minutes most days of the week
- Cycling: 20-30 minutes, 3-5 times per week at a moderate pace
- Swimming: 20-40 minutes, 3-4 times per week at a relaxed pace
- Stretching: 15-30 minutes, 3-4 times per week
- Light strength training: 2-3 sessions per week, using light weights (1-5 kg) or resistance bands
Stress management for Angina patients:
1. Practice deep breathing & relaxation techniques
- Simple deep breathing exercise
- Inhale deeply through the nose for 4 seconds
- Hold the breath for 4 seconds
- Exhale slowly through mouth for 6-8 seconds
- Repeat 5-10 times whenever you feel stressed
2. Get enough quality sleep:
- Stick to a consistent sleep schedule
- Avoid screens (phones, TV) 30-60 min before bed
- Try a calming bedtime routine like reading, herbal tea, or meditation
Drug – Drug interaction
Before
taking Flavedon MR 35mg Tablet, inform your doctor if you are taking
any other medicines, including medicines obtained without the
prescription:
1. Beta-blockers (e.g., Metoprolol, Atenolol, Propranolol)
- Potential Interaction: Combining Flavedon MR with beta-blockers may cause excessive fatigue, dizziness, or low heart rate
- May increase the risk of low blood pressure
2. Calcium channel blockers (e.g., Amlodipine, Diltiazem, Verapamil)
- Potential Interaction: It can cause excessive vasodilation leading to dizziness, headaches, or swelling in the legs
- It may also enhance the anti-anginal effects, which is beneficial but requires monitoring
3. Antiarrhythmic drugs (e.g., Amiodarone, Digoxin, Quinidine)
- Potential Interaction: Flavedon MR may affect heart conduction, possibly increasing the risk of irregular heartbeat
- Amiodarone + Flavedon MR can cause an additive effect on heart rate control, leading to bradycardia
4. Dopamine agonists (e.g., Levodopa, Pramipexole, Ropinirole)
- Potential Interaction: Flavedon MR may worsen Parkinsonism symptoms (tremors, rigidity, movement disorders)
- Long-term use of Flavedon MR has been linked to the development of drug-induced movement disorders
5. Strong CYP3A4 inhibitors (e.g., Ketoconazole, Ritonavir, Erythromycin, Clarithromycin)
- Potential Interaction: These drugs reduce Flavedon MR metabolism, increasing its concentration in the body
- Higher drug levels may lead to increased dizziness, nausea, or hypotension
Synopsis
| Drug | :Â Â | Trimetazidine |
| Pharmacological Category | :Â Â | Anti-anginal drugs |
| Therapeutic Indication | :  | Angina pectoris        |
| Dosage Forms | :Â Â | Tablet, Capsule |
More Information
Angina Pectoris:
What is Angina Pectoris?
Angina
pectoris is chest pain or discomfort caused by reduced blood flow to
the heart muscle. It is a symptom of coronary artery disease (CAD),
where the arteries supplying blood to the heart become narrowed or
blocked due to plaque buildup (atherosclerosis).
Causes of Angina: Angina occurs when the heart does not receive enough oxygen-rich blood to meet its demands. The most common causes include:
- Coronary artery disease (CAD)
- High blood pressure (hypertension)
- Anemia
- Heart valve disease
- Stress & anxiety
- Cold weather or large meals
Symptoms of Angina
- chest pain or discomfort (may spread to the arms, neck, jaw, shoulders, or back)
- shortness of breath
- fatigue or dizziness
- nausea or sweating
- pain triggered by physical exertion or stress and relieved by rest
Management of Angina
- Lifestyle changes – quit smoking, exercise regularly, manage stress, practice meditation, or deep breathing and maintain a healthy weight
- Medications for Angina: Nitrates beta-blockers, Calcium channel blockers, Antiplatelet drugs, Flavedon MR (trimetazidine)
- Medical procedures (for severe cases): Angioplasty & sent placement, Coronary artery bypass surgery (CABG)
2. Ischemic Heart Disease:
What is Ischemic Heart Disease (IHD)?
Ischemic
Heart Disease (IHD), also known as Coronary Artery Disease (CAD),
occurs when the heart’s blood supply is reduced due to the narrowing or
blockage of coronary arteries. This is primarily caused by
atherosclerosis, a condition where fatty deposits (plaque) build up
inside the arteries.
Why is IHD serious?
- Reduced blood flow leads to angina (chest pain)
- Severe blockage can result in a heart attack (myocardial infarction)
- Long-term IHD can lead to heart failure or arrhythmias (irregular heartbeats)
Modifiable risk factors (Things you can control)
- High Blood Pressure Â
- High Cholesterol
- Smoking
- Diabetes
- Obesity
- Physical inactivity
- Unhealthy diet
- Stress
- Excessive alcohol consumption
Non-Modifiable Risk Factors (Things you cannot control)
- Age: Risk increases after 45 years (men) and 55 years (women)
- Gender: Men are at higher risk, though postmenopausal women also face increased risk
- Family History
- Genetic Factors
Flavedon MR vs Alternative Medications:
|
Condition |
Best Alternative to Flavedon MR |
|
High Blood Pressure + Angina |
Beta-Blockers or Calcium Channel Blockers |
|
Need Quick Relief from Angina Attacks |
Nitrates (Nitroglycerin) |
|
Cannot Tolerate BP-Lowering Medications |
Flavedon MR or Ranolazine |
|
Diabetic Patients with Angina |
Flavedon MR or Ranolazine |
|
Patients with Arrhythmias |
Flavedon MR (safer than Ranolazine) |
When to expect results: How long does Flavedon MR take to work?
|
Stage |
Expected timeline |
What happens? |
|
Initial effects |
1-2 weeks |
Some patients may notice mild improvements in Angina symptoms |
|
Noticeable symptom relief |
4-6 weeks |
Angina attacks become less frequent, and exercise tolerance may improve |
|
Full benefits |
8-12 weeks |
Maximum heart-protective effects are reached |
FAQs About FLAVEDON MR 35MG TABLET
Q: What is Flavedon MR 35mg used for?
A:
Flavedon MR 35mg used is used in adult patients for the management of
angina pectoris (chest pain caused by a heart disease) along with other
medicines. It protects the heart cells from the effects of a reduced
oxygen supply during an episode of angina.
Q: How does Flavedon MR 35mg work?
A:
Flavedon MR 35mg Tablet works by optimizing metabolism of fatty acids
and glucose, thereby allowing more blood flow and oxygen supply to the
heart. It also reduces the thickening and scarring of heart tissue. This
results in reducing chest pain due to blood vessel narrowing or
blocking. Â
Q: Can Flavedon MR 35mg be taken during pregnancy?
A: There is insufficient clinical data on the safety of Trimetazidine in pregnant women.
Q: Where to buy Flavedon MR 35mg Online?
A: You can purchase Flavedon MR 35mg tablets online in India through reputable pharmacy like Netmeds.
Q: Is it safe to consume alcohol while taking Flavedon MR 35mg?
A:
It is not advisable to consume alcohol while taking Flavedon MR 35mg
(Trimetazidine) due to potential interactions and health risks.
Q: Is Flavedon MR 35mg safe for long-term use?
A:
It is safe for long-term use in most patients with chronic angina or
ischemic conditions. Regular monitoring of kidney function and
neurological symptoms is advised, especially in elderly patients.
Consult your doctor for periodic assessments to ensure continued safety.
Q: Is Flavedon MR 35mg good for the heart?
A:
Yes. Flavedon MR 35mg is good for the heart in adult patients suffering
from angina pectoris (chest pain caused by a heart disease). It
protects the heart cells from the effects of a reduced oxygen supply
during an episode of angina.
Q: Can Flavedon MR 35mg lower blood pressure?
A:
Flavedon MR 35mg can cause a fall in blood pressure on standing-up
occasionally, thereby causing dizziness, light headiness or fainting,
malaise (feeling of being unwell), dizziness, and fall flushing. Contact
your doctor or a nearby hospital immediately.
Q: How long should I take Flavedon MR 35mg Tablet?
A:
Take Flavedon MR 35mg Tablet as advised by your physician. Your doctor
will decide the correct dose and duration for you depending upon your
age, body weight, and disease condition.
Q: What are the common side effects of Flavedon MR 35mg Tablet?
A:
The common side effects associated with Flavedon MR 35mg Tablet are
dizziness, nausea, stomach pain. Consult your doctor if the condition
persists for long or worsens.
Q: When should I stop taking Flavedon MR 35mg Tablet?
A:
Stop taking Flavedon MR 35mg Tablet and consult your doctor immediately
if you experience signs of low blood pressure (dizziness, light
headiness or fainting, malaise, dizziness, and fall flushing), low
platelet count (frequent bruising, superficial bleeding, and prolonged
bleeding from wounds), and low white blood cell count that increases
vulnerability to infections.
Q: Who should avoid taking Flavedon MR 35mg Tablet?
A:
Flavedon MR 35mg Tablet is not recommended for use if you have
Parkinson disease, kidney-related problems, or are allergic to
trimetazidine.
Q: Is Flavedon MR 35mg Tablet safe for kids?
A:
There is insufficient research on the safety and effectiveness of
Flavedon MR 35mg in pediatric patients. It is primarily prescribed for
adults with angina and ischemic heart disease.
References
1. KD. Tripathi. Corticosteroids. Essentials of Medical Pharmacology. Seventh edition. 2013. Page 553-554.
2.
Yuri M. Pozdnyakov. Clinical Acceptability of Trimetazidine Modified
Release 80 mg Once Daily Versus Trimetazidine Modified-Release 35 mg
Twice Daily in Stable Angina Pectoris. National Library of Medicine.
PubMed Central. June 2018. [Assessed on 14 February 2025]Â 
3.
Kirti Gupta, Sneha Pandey, Newly Bagang, Kamalpreet Mehra, and
Gaaminepreet Singh. Trimetazidine, an emerging paradigm in renal
therapeutics: preclinical and clinical insights. National Library of
Medicine. PubMed Central. November 2021. [Assessed on 14 February 2025] Â
4.
Agustin Ciapponi, Rudolf Pizarro, and Jeff Harrison. Trimetazidine for
stable angina. National Library of Medicine. PubMed Central. March 2017.
[Assessed on 14 February 2025] Â
5.
European Medicine Agency. Assessment Report for
trimetazidine-containing medicinal products. [Revised in September 2012]
[Assessed on 14 February 2025] Â
6.
Servier (Ireland) Industries Ltd. Health Product Regulatory Authority.
[Revised in February 2021] [Assessed on 14 February 2025] Â
7. VIANEX S.A. Health Product Regulatory Authority. [Revised in April 2016] [Assessed on 14 February 2025] Â
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| Weight | 17.5 g |
|---|
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