INTRODUCTION ABOUT GASTRACTIV TABLET
GASTRACTIV
TABLET contains Domperidone which belongs to the group of medicines
called Dopamine antagonists. It is used in the management of nausea and
vomiting associated with central or local origin, chemotherapy or
radiotherapy, drugs or migraine.
Nausea and vomiting are not a
disease but symptoms of different conditions such as infections, food
poisoning, motion sickness, overeating, blocked intestine, migraine,
indigestion and many more.
GASTRACTIV TABLET can also be used for
relief of postprandial symptoms of fullness, nausea, epigastric
bloating and belching (burping) that is occasionally accompanied by
stomach discomfort and heartburn.
GASTRACTIV TABLET is not
recommended for use in patients having heart or moderate to severe liver
diseases, bleeding in the stomach or intestines, blockage or tear in
your intestines, and tumors in the pituitary gland (prolactinoma).
GASTRACTIV TABLET should be used with caution in patients having kidney
diseases.
GASTRACTIV TABLET should be used with caution in
pregnant women and should be used in breastfeeding women only if
considered clearly necessary by the doctor. Ask for your doctor’s advice
before taking it. GASTRACTIV TABLET should be used with caution in
elderly patients (above 60 years of age).
GASTRACTIV TABLET
should not be used in children below 12 years or weighing less than
35kgs. Consult with your child’s doctor. The common side effect of
taking GASTRACTIV TABLET includes a dry mouth. Consult with your doctor
if this worsens or doesn’t improve.
USES OF GASTRACTIV TABLET
Prevents nausea and vomiting associated with:
- central or local origin
- chemotherapy or radiotherapy
- drugs
- migraine
Relieves:
- postprandial
symptoms of fullness, nausea, epigastric bloating and belching
(burping) that is occasionally accompanied by stomach discomfort and
heartburn
HOW GASTRACTIV TABLET WORKS
GASTRACTIV
TABLET is has an anti-emetic property which acts by blocking a chemical
messenger in the brain called dopamine, that transfers information
through nerve endings. GASTRACTIV TABLET functions by inhibiting the
muscle contraction that occurs naturally in the digestive system and
enhances the peristaltic movement in the food pipe which helps in
facilitating the digestion time faster, this causes calming down effect,
thereby relieving nausea or vomiting sensation.
DIRECTIONS FOR USE
Take GASTRACTIV TABLET as advised by your physician. It can be taken before meals.
For Tablet, Capsule: Swallow GASTRACTIV TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse GASTRACTIV
TABLET in the specified quantity of water as mentioned on the label.
Consume the mixture immediately after reconstitution.
Your doctor
will decide the correct dose and duration of therapy for you depending
on your age, body weight and disease condition. Continue to take
GASTRACTIV TABLET for the stipulated duration prescribed by your doctor
to achieve better results.
SIDE EFFECTS OF GASTRACTIV TABLET
COMMON
- dry mouth
UNCOMMON
- decrease in sexual drive (libido) in men
- feeling anxious
- feeling drowsy
- headaches
- diarrhoea
- itchy skin, rash
- unusual production of breast milk (men and women)
- painful or tender breasts
- general feeling of weakness
RARE
Stop taking GASTRACTIV TABLET and consult your doctor immediately if you experience any of the following side effects
- severe
allergic reaction having symptoms such as swelling of the hands, feet,
ankle, face, lips and throat which may cause difficulty in swallowing or
breathing - itchy lumpy rash (hives), nettle rash (urticaria)
- uncontrolled
movements, which include irregular movements of eyes, an unusual move
of the tongue, abnormal posture (Ex. twisted neck, trembling and muscle
stiffness) - have a fast unusual heartbeat
- seizures (fits)
HOW TO MANAGE SIDE EFFECTS
Dry mouth:
Dry
mouth can be managed by chewing sugar-free gum or sucking on sugar-free
hard candies to stimulate the flow of saliva. Sip water at regular
intervals of time. Do not use mouthwashes that contain alcohol because
they can be drying. Consult your physician for advice.
diarrhoea:
Drink
lots of fluids, such as water or fruit juice to keep yourself hydrated.
Do not consume any medicine on your own without consulting your doctor.
Ask for your doctor’s advice if diarrhoea doesn’t improve.
Headache:
Try
to take rest and don’t involve yourself in exertive activities. Rest in
a quiet and dark room. Apply a pain-relieving balm on your forehead.
Ask for your doctor’s advice if the headache doesn’t improve
Drowsiness:
Take
adequate sleep. Do not involve in rigorous activities. Do not interfere
with your sleep cycle. Talk to your doctor if the drowsiness doesn’t
improve.
Itchy skin:
Hot water makes your
skin irritated, so avoid taking hot showers. Do not scratch the
affected area. Use sunscreen and protective clothing when outdoors. To
soothe and hydrate the irritated skin, apply moisturizers. Contact your
doctor if the itching worsens.
WARNING & PRECAUTIONS
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PREGNANCY
GASTRACTIV TABLET should be used with caution in pregnant women. Consult your doctor before taking it.
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BREASTFEEDING
GASTRACTIV
TABLET is not recommended for use in breastfeeding women as it may pass
through breast milk. GASTRACTIV TABLET may cause unwanted side effects
affecting the heart in a breastfed baby. It should only be used only if
considered clearly necessary by the doctor. Consult your doctor before
taking GASTRACTIV TABLET.
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DRIVING AND USING MACHINES
GASTRACTIV
TABLET does not affect the ability to drive or use machines. Yet do not
drive or operate any machines if you feel dizzy after taking GASTRACTIV
TABLET.
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KIDNEY
GASTRACTIV
TABLET should be taken with caution in patients with kidney problems
such as kidney impairment or kidney failure. Your doctor might consider
adjusting your dose. Consult your doctor before taking it.
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ALLERGY
Do not take GASTRACTIV TABLET if you are allergic to domperidone or any other ingredients present in it.
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HEART DISEASE
GASTRACTIV
TABLET is not recommended in patients suffering from heart problems
such as prolonged QT corrected interval (reading in eco cardiogram (ECG)
machine) or heart failure (heart cannot pump blood properly). Kindly
consult a doctor before taking GASTRACTIV TABLET.
OTHERS
GASTRACTIV TABLET is not recommended for use if you:
- tumor in the pituitary gland (prolactinoma)
- history of blockage or tear in the intestine
- hypokalemia (low level of potassium)
- hyperkalemia (high level of potassium in the blood)
- hypomagnesemia (low level of magnesium in the blood)
- signs and symptoms of bleeding in the stomach or intestine (black tarry bowel motions or blood in your bowel motions)
Use in pediatrics:
GASTRACTIV
TABLET is not recommended for use in children below 12 years of age or
weighing less than 35 kgs. Consult with your child’s doctor before
giving GASTRACTIV TABLET to your child.
Use in geriatrics:
GASTRACTIV
TABLET should be used with caution for use over 60 years of age, as
GASTRACTIV TABLET be associated with an increased risk of heart rhythm
disorder and cardiac arrest. Consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug interactions:
Before taking GASTRACTIV TABLET, inform your doctor if you are taking any of the following medicines:
- medicines to manage fungal infections (Ex. ketoconazole, fluconazole, and voriconazole)
- medicines to manage bacterial infections (Ex. erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine)
- medicine
to manage heart problems or high blood pressure (Ex. amiodarone,
dronedarone, quinidine, disopyramide, bepridil, dofetilide, sotalol,
diltiazem, verapamil) - medicines to manage psychoses (Ex.
haloperidol, pimozide, sertindole), medicine to manage depression (Ex.
citalopram, escitalopram) - medicines to manage gastrointestinal disorders (such as cisapride, diphemanil, dolasetron, prucalopride)
- medicines to manage allergies (Ex. mequitazine, mizolastine)
- medicine to manage malaria (specifically halofantrine)
- medicines to manage AIDS/HIV (Ex. ritonavir, atazanavir)
- medicine to manage cancer (Ex. toremifene, vandetanib, vincamine)
- medicine used to manage drug addiction (Ex. methadone)
Overdosage:
If
you or anyone else accidentally took too much of GASTRACTIV TABLET,
consult your doctor immediately. The symptoms might include feeling
sleepy, confused, uncontrolled movements of the eye and tongue and
abnormal posture (like a twisted neck).
SYNOPSIS
| Drug | : | Domperidone |
| Pharmacological Category | : | Dopamine antagonists |
| Therapeutic Indication | : | Nausea and Vomiting |
| Dosage Forms | : | Tablets, Capsules, Dispersible tablets, Rapitab, Suspension, Oral Suspension, Syrup, Oral Drops, Drops |
MORE INFORMATION
- Keep GASTRACTIV TABLET out of reach of children
- Store GASTRACTIV TABLET at room temperature below 30°C
FAQs ABOUT GASTRACTIV TABLET
What is GASTRACTIV TABLET and why is it prescribed?
GASTRACTIV
TABLET contains Domperidone which belongs to the group of medicines
called Dopamine antagonists. It is used in the management of nausea and
vomiting associated with central or local origin, chemotherapy or
radiotherapy, drugs or migraine. GASTRACTIV TABLET can also be used in
relief of postprandial symptoms of fullness, nausea, epigastric bloating
and belching (burping) that is occasionally accompanied by stomach
discomfort and heartburn.
How long can I take GASTRACTIV TABLET?
It
is recommended that GASTRACTIV TABLET be taken for the shortest period
and at the lowest dose. This is because GASTRACTIV TABLET can cause an
irregular heartbeat when taken for a longer period or at a high dose.
Ask for your doctor’s advice.
Can I take GASTRACTIV TABLET with antibiotics?
Use
of GASTRACTIV TABLET with antibiotics like erythromycin, levofloxacin,
and some antifungals is not recommended as this can cause interaction.
Please consult your doctor for advice before using any antibiotics with
GASTRACTIV TABLET.
Does GASTRACTIV TABLET increase milk secretion?
Yes,
GASTRACTIV TABLET can increase milk secretion also known as
galactorrhoea. This is an uncommon side effect of using GASTRACTIV
TABLET. Talk to your doctor if you are experiencing this side effect
while taking this medicine.
Does GASTRACTIV TABLET cause heart problems?
GASTRACTIV
TABLET may be associated with an increased risk of heart problems (like
an irregular heartbeat) and heart attacks. The risk also increases when
GASTRACTIV TABLET is given together with other medicines. Inform the
doctor of your medication history when taking GASTRACTIV TABLET.
Does GASTRACTIV TABLET cause dry mouth?
Yes,
GASTRACTIV TABLET can cause dry mouth. A dry mouth can be managed by
chewing sugar-free gum or sucking on sugar-free hard candies to
stimulate the flow of saliva. Sip water at regular intervals of time. Do
not use mouthwashes that contain alcohol because they can be drying.
Consult your physician for advice.
What is the best time to take GASTRACTIV TABLET?
It
is recommended to take GASTRACTIV TABLET before meals. If taken after
meals, absorption of the medicine is somewhat delayed. Patients should
try to take each dose of GASTRACTIV TABLET at a scheduled time to avoid
missing a dose.
| Weight | 17.5 g |
|---|
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