INTRODUCTION ABOUT OXALTERO 100MG INJECTION
OXALTERO 100MG INJECTION contains Oxaliplatin which belongs to the group of medicine called Anticancer drugs. It is used to manage cancers of the colon and/or rectum. It is highly used in combination with other anti-cancer medicines (such as 5-flurouracil and folinic acid) as an adjunct to manage stage III colon cancer after removing the primary tumour. It can also be used to manage metastatic colorectal cancer (cancer of colon and rectum that has been spread to other parts of the body).
Before receiving OXALTERO 100MG INJECTION inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have low white blood count in your blood or recently received or planning to receive any vaccination in the upcoming days.
OXALTERO 100MG INJECTION is not recommended for use in pregnant or breastfeeding women and in children aged below 18 years. Men and women receiving OXALTERO 100MG INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with OXALTERO 100MG INJECTION.
The most common side effects of receiving OXALTERO 100MG INJECTION are tingling and numbness of body parts, abnormal sensation in the throat, nausea, vomiting, stomach pain, headache, dizziness, tiredness, weight loss, changes in taste, skin rash, hair loss, mouth ulcers and low blood calcium levels. Contact your doctor if any of these side effect worsens.
USES OF OXALTERO 100MG INJECTION
It is used to manage:
- Colon cancer (stage III)
- Metastatic colorectal cancer
HOW OXALTERO 100MG INJECTION WORKS
OXALTERO 100MG INJECTION is an anticancer medication. It works by damaging the DNA (genetic material) of the cancer cells. As a result, it reduces abnormal growth and multiplication of cancer cells in the body.
DIRECTIONS FOR USE
OXALTERO 100MG INJECTION will be given to you only by a doctor or a nurse into a vein (as an intravenous infusion).
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF OXALTERO 100MG INJECTION
COMMON
- nerve pain, tingling and numbness of body parts
- abnormal sensation in the throat, problems in breathing
- diarrhea, nausea, vomiting, constipation, stomach pain
- indigestion, heartburn, hiccups
- low blood counts (causing bleeding, anemia and increased infections)
- injections site reactions (pain and discomfort)
- fever, shakiness, headache, dizziness, tiredness, body pains
- weight loss, lack of appetite
- changes in taste, nasal bleeds
- skin rash, itching, flaky skin, hair loss, flushing
- nail disorder, increased sweating
- joint pain
- passing little or no urine
- high blood pressure
- depression and lack of sleep
- low blood calcium levels
- neck stiffness
UNCOMMON
- nervousness
RARE
- loss of hearing
Contact your doctor immediately if you experience any of the following side effects after receiving OXALTERO 100MG INJECTION:
- signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
- mouth ulcers (oral sores)
- low platelet count in blood causing excessive unusual bruising
- dry cough, difficulty in breathing and crackling sounds
- sepsis (blood infections)
- low WBC count causing fever or flu-like symptoms
- signs of blood clots in lungs (chest pain, difficulty in breathing, coughing up blood)
- blockage or swelling in the intestines
- problems in hearing, ringing sound in the ears and spinning sensation
- severe persistent diarrhea and vomiting
- short-term vision loss
- signs of reversible posterior leukoencephalopathy syndrome (a nerve disorder causing headache, altered mental functioning, seizures and abnormal vision from blurriness to vision loss)
- signs of Haemolytic-uraemic syndrome (such as extreme tiredness, low RBC count, shortness of breath, low platelet count, abnormal bruising, passing little or no urine)
- inflammation of the lungs
- pain in upper abdomen and back with nausea and vomiting
- vascular disorders of the liver (symptoms include abdominal pain and swelling, weight gain and tissue swelling of the feet, ankles or other parts of the body)
- bleeding in the gut causing bloody stools or vomits
HOW TO MANAGE SIDE EFFECTS
Skin rash:
Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Consult your doctor if your headache worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Consult your doctor if your dizziness worsens.
Nausea and Vomiting:
Stick to simple meals. Avoid eating oil rich or spicy foods. If your nausea worsens, consult your doctor for advice.
Mouth ulcers:
Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on the affected areas of the mouth if required. Consult your doctor if the symptom did not improve.
Diarrhoea:
Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to manage diarrhoea and consult your doctor if the symptom gets worse.
Constipation:
Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for constipation.
WARNING & PRECAUTIONS
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PREGNANCY
OXALTERO 100MG INJECTION is generally not recommended for use in pregnant women. However, consult your doctor before receiving it. Women of childbearing potential must use a suitable contraceptive to avoid pregnancy while undergoing therapy with OXALTERO 100MG INJECTION and until 4 months after stopping the therapy. If you accidentally became pregnant while receiving OXALTERO 100MG INJECTION, inform your doctor immediately.
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BREASTFEEDING
OXALTERO 100MG INJECTION is not recommended for use in women who are breastfeeding. Therefore, consult your doctor before receiving it.
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DRIVING AND USING MACHINES
Do not drive or operate any machines if your ability is affected by OXALTERO 100MG INJECTION.
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KIDNEY
OXALTERO 100MG INJECTION is not recommended to use in patients with severe kidney problems. It should be used with caution in patients with mild to moderate kidney problems. Therefore, consult your doctor before receiving it.
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LIVER
OXALTERO 100MG INJECTION should be used with caution in patients with liver problems. Therefore, consult your doctor before receiving it.
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ALLERGY
Talk to your doctor before receiving OXALTERO 100MG INJECTION if you are allergic to Oxaliplatin or to any other platinum-based anticancer medicines (such as carboplatin, cisplatin).
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HEART DISEASE
OXALTERO 100MG INJECTION should be used with caution in patients with heart problems (such as prolongation of the QT interval, an irregular heartbeat). It should also be used with caution in patients having a family history of heart problems. Therefore, consult your doctor before receiving it.
OTHERS
OXALTERO 100MG INJECTION is not recommended for use if you have:
- reduced number of blood cells
- tingling and numbness in the fingers and/or toes
- difficulty in performing delicate tasks (such as buttoning clothes)
Inform your doctor, before receiving OXALTERO 100MG INJECTION, if you:
- recently received any vaccine or plan to receive any vaccines
Use in pediatrics:
OXALTERO 100MG INJECTION is generally not recommended for use in children and adolescents (under 18 years of age). Therefore, consult your doctor before receiving it.
Use in geriatrics:
OXALTERO 100MG INJECTION should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before receiving it.
INTERACTIONS
Drug-Drug interactions:
Inform your physician, before receiving OXALTERO 100MG INJECTION, if you are taking any of the following medicines such as:
- other medicines used to manage cancer (Ex. 5-fluorouracil, paclitaxel)
- medicines used as antibiotics (Ex. erythromycin)
- medicines used to relieve pain (Ex. salicylates)
- medicines used for vomiting (Ex. granisetron)
- medicines used to manage epilepsy (Ex. sodium valproate)
- live or attenuated vaccines (Ex. yellow fever vaccine)
Overdosage:
OXALTERO 100MG INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor if you experience any unusual symptoms.
SYNOPSIS
| Drug | : | Oxaliplatin |
| Pharmacological Category | : | Platinum-based chemotherapy agent |
| Therapeutic Indication | : | Colorectal cancer |
| Dosage Forms | : | Injection, Infusion |
MORE INFORMATION
- Keep OXALTERO 100MG INJECTION out of reach of children
- Store OXALTERO 100MG INJECTION below 25°C
| Weight | 25 g |
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