INTRODUCTION ABOUT SEROFLO 250 INHALER
SEROFLO 250 INHALER is a combination of Fluticasone and Salmeterol which belongs to the group of medicines called Corticosteroids and Bronchodilators respectively. It is used to manage asthma and chronic obstructive pulmonary disease (COPD). It also helps in reducing the flare-ups of COPD symptoms.
Asthma is a long-term respiratory disease in which your airways become inflamed, swollen and narrowed. It also causes excessive mucous secretion in the airways which makes it difficult for the air to pass through, leading to unpleasant symptoms like wheezing, difficulty in breathing, chest pain and/or cough.
COPD is a lung disease characterized by chronic lung inflammation and obstructed air flow within the airways. It causes wheezing, breathing difficulties, cough with mucus production and chest pain.
Use SEROFLO 250 INHALER every day until your doctor tells you to stop. It is meant for inhalation use only, and therefore do not the swallow the medicine. Do not stop using this medicine once your symptoms subside without consulting your doctor. It is suitable for use both in adults and in adolescents (aged 12 years or above).
SEROFLO 250 INHALER should not be used to relieve a sudden asthma attack (such as sudden breathing problems). Instead contact your doctor or use a fast-acting ‘rescue’ inhaler containing salbutamol to subside the symptoms.
Before using SEROFLO 250 INHALER inform your doctor if you have any lung infections, liver problems or heart problems. You must also inform your doctor if you have diabetes, hypertension, fits, overactive thyroid functions, osteoporosis, adrenal gland problems or a weak immune system as a precaution.
SEROFLO 250 INHALER should be used in pregnant and breastfeeding women only if it is considered necessary by the physician. The most common side effects of using SEROFLO 250 INHALER are headache, cold, oral thrush or oral sores, throat irritation, hoarse voice, muscle pain and joint pain. Contact your doctor if any of these side effect worsens.
USES OF SEROFLO 250 INHALER
It is used to manage, manage the symptoms of:
- Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
HOW SEROFLO 250 INHALER WORKS
SEROFLO 250 INHALER is a combination of two medicines namely, fluticasone and salbutamol. Fluticasone is an inhalation corticosteroid. It blocks the release of certain chemical messengers in the airways (such as prostaglandins, leukotrienes) that cause inflammation and swelling.
Salmeterol is a bronchodilator. It relaxes the smooth muscles of the airways and widens them. Collectively, they reduce airway inflammation, allows the air to pass through more freely and makes breathing easier.
DIRECTIONS FOR USE
Use SEROFLO 250 INHALER medicine every day until your doctor tells you to stop. It is meant for inhalation only. Inhale the medicine only through your mouth into the lungs and not via nose.
Follow the instruction given in the enclosed leaflet.
- prime the device by releasing two puffs of the medicine into the air
- place the mouthpiece in your mouth between your teeth and ensure completely closure
- breathe in slowly and deeply using your mouth through the mouthpiece while simultaneously pressing the top of the canister firmly to release a puff of medicine
- remove the device from your mouth and hold your breath for about 10 seconds or for as long as is comfortable
- wait about 30 seconds between taking each puff of medicine
- after inhalation, wipe the mouthpiece with a dry tissue and close the device after use
- once inhalation is over, rinse your mouth with water and spit it out or brush your teeth
Your doctor will decide the correct dose, duration and number of puffs for you depending upon your age, body weight and disease condition.
Do not start using this medicine unless your doctor or health care provider has taught you how to use and you understand how to use it correctly. If you find it difficult to use this device, your doctor may recommend you a suitable spacer device.
Do not stop taking this medicine abruptly or reduce the dose without consulting your doctor, as it could make your breathing even worse.
SIDE EFFECTS OF SEROFLO 250 INHALER
COMMON
- headache
- common cold
- thrush in the mouth or throat (a yeast infection that causes sore, creamy-yellow, raised patches)
- sore tongue, hoarse voice, throat irritation
- muscle pain or cramps
- joint pain and swelling
- bruising and fractures
- inflammation of sinuses
- signs of low levels of potassium in blood (such as an uneven heartbeat, muscle weakness or cramps)
UNCOMMON
- diabetes (increased blood sugar levels)
- cataract (cloudy eyes)
- unusually fast or uneven heartbeat, tremor (feeling shaky)
- chest pain
- feeling worried, disturbance in sleep
- allergic skin rash
RARE
- slowing of growth in adolescents, bone thinning, glaucoma, weight gain
- Cushing’s Syndrome (a disorder caused due to release of high levels of cortisol)
- changes in behavior (such as being unusually active and irritable)
- fungal infection in the esophagus which causes difficulties in swallowing
Stop using SEROFLO 250 INHALER and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as sudden wheezing, cough, shortness of breath, skin rash, itching, swelling of the face, lips, tongue, or throat, breathing difficulties, sudden fast heartbeat which can cause fainting, light-headedness, collapse or even loss of consciousness)
- sign of pneumonia (a lung infection accompanied with fever, chills, increased cough production, increased breathing difficulties, excessive mucus production and change in mucus color)
HOW TO MANAGE SIDE EFFECTS
Headache: Â
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.
Throat irritation:
Gargle your throat with salt water twice a day. Always try to drink warm water. Avoid chilled, cooled, or sweetened food items or beverages. Drinking turmeric milk or ginger tea mixed with honey and pepper powder can ease the soreness. Consult your doctor if the symptom did not improve.
Muscle pain or cramps:
Rub a pain-relieving balm or place a heat pack on the affected area for some time, as it could ease the pain. Do not move the affected area frequently. Try to do some simple movements every day which would improve blood circulation and reduce further incidence of muscle pain. Try to eat a well-balanced protein rich diet, so that it can help to repair and rebuild the damaged muscle. Consult your doctor if the symptom did not improve.
Joint pain:
Rub a pain-relieving balm or place a heat pack on the affected area for some time, as it could ease the pain. Do not move the affected area frequently. Consume calcium and vitamin supplements regularly, particularly if you are elderly. Consult your doctor if the symptom did not improve.
Allergic skin rash:
Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if the symptom did not improve.
WARNING & PRECAUTIONS
PREGNANCY
SEROFLO 250 INHALER should be used in pregnant women only if it is considered necessary by the doctor. Your doctor may prescribe this medicine after outweighing the risk and benefits to you and your baby. Therefore, inform your doctor before using it.
BREASTFEEDING
SEROFLO 250 INHALER should be used in breastfeeding women only if it is considered necessary by the doctor. Therefore, consult your doctor for advice before using it.
DRIVING AND USING MACHINES
Do not drive or operate any heavy tools or machines if your ability is affected by SEROFLO 250 INHALER.
LIVER
SEROFLO 250 INHALER should be taken with caution in patients with liver diseases. Therefore, consult your doctor before using it.
ALLERGY
Do not use SEROFLO 250 INHALER if you are allergic to Salmeterol or Fluticasone.
LUNGS
SEROFLO 250 INHALER should be taken with caution among patients who have or previously had any Tuberculosis or any other lung infections. Therefore, consult your doctor before using it.
HEART DISEASE
SEROFLO 250 INHALER should be taken with caution in patients with heart diseases (such as irregular or fast heartbeat). Therefore, consult your doctor before using it.
OTHERS
SEROFLO 250 INHALER is not recommended for use in patients having:
- status asthmaticus (respiratory failure)
- acute asthma attacks
Before using SEROFLO 250 INHALER, inform your physician if you:
- have an over-active thyroid gland
- have diabetes
- have high blood pressure
- have hypokalemia (low levels of potassium in blood)
- have fits (seizure)
- have osteoporosis (weak bones)
- have a weak immune system
- have or had eye problems (such as glaucoma, increased pressure in the eyes, cataracts)
- have viral, bacterial or fungal infections (Ex. measles, chickenpox)
- have glucose intolerance
- have problems in adrenal gland (Ex. adrenal insufficiency)
- met with any major trauma (accidents) or undergone a surgery
Use in pediatrics:
SEROFLO 250 INHALER is not recommended for use in children younger than 12 years of age. Kindly consult your doctor before using it.
Use in geriatrics:
SEROFLO 250 INHALER should be taken with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before using it. Proper dose adjustments and careful monitoring are required in such patients.
INTERACTIONS
A. Drug-Drug interactions:
Before using SEROFLO 250 INHALER, inform your physician if you are taking any of the following medicines such as:
- other beta-blockers (used to manage high blood pressure or other heart conditions) Ex. atenolol, propranolol and sotalol
- medicines used to manage fungal infection (such as ketoconazole and itraconazole)
- medicines used to manage HIV infection (Ex. ritonavir, atazanavir, indinavir, nelfinavir, saquinavir or cobicistat)
- clarithromycin, erythromycin (used to manage bacterial infections)
- other corticosteroids (taken orally or via injections to manage pain or inflammation) Ex. dexamethasone
- potassium-sparging diuretics (used to manage high blood pressure by increasing urine output) Ex. spironolactone, acetazolamide
- other medicines that can cause bronchodilation (such as salbutamol, formoterol)
- xanthine medicines (used to manage asthma) Ex. theophylline and aminophylline
- nefazodone (used to manage depression)
- medicines used to manage depression such as (rasagiline, selegiline, phenelzine, amitriptyline, nortriptyline, doxepin, imipramine, desipramine)
Overdosage:
If you or anyone else accidentally inhaled excessive amount of this medicine, contact your doctor immediately or go to the hospital straight away. Symptoms of overdosage might include shortness of breath, chest pain, fast heartbeat, feeling shaky, dizziness, headache, muscle weakness and joint pain.
SYNOPSIS
| Drug | : | Fluticasone, Salmeterol |
| Pharmacological Category | : | Corticosteroids, Beta-1 receptor agonists |
| Therapeutic Indication | : | Asthma, COPD |
| Dosage Forms | : | Autohaler, Blisters, Capsule, Inhalation capsule, Octacaps, Respicaps, Rotacaps, Trans caps, Nexcaps, Accuhaler, Inhaler, Ciphaler, Multihaler |
MORE INFORMATION
- Keep SEROFLO 250 INHALER out of reach of children
- Store SEROFLO 250 INHALER at room temperature
| Weight | 50 g |
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