PASILOW 50 Capsule 5’s
₹294.34
5 Capsule(s) in a Strip *
Mkt: Glenmark Pharmaceuticals Ltd
* Country of Origin: India *
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Introduction About PASILOW 50 CAPSULE
PASILOW
50 CAPSULE contains Cyclosporine which belongs to the group of
medicines called Immunosuppressants. It is used to manage graft
rejection in patients undergoing transplantation of any organ, bone
marrow or stem cells.
It can also be used to manage various
auto-immune disease conditions such as psoriasis, atopic dermatitis (or
eczema), rheumatoid arthritis (joint inflammation), nephrotic syndrome
(a kidney disease) or eye inflammation (such as endogenous uveitis,
including Behçet’s uveitis). It is mostly used in combination with other
immune suppressants (such as azathioprine) to achieve maximum benefits.
Take
PASILOW 50 CAPSULE regularly as instructed by your doctor. While
undergoing therapy with PASILOW 50 CAPSULE your doctor will periodically
monitor your blood pressure, blood cholesterol levels, liver and kidney
functions to avoid the risk of side effects.
Your doctor may
also prescribe you blood tests and urine tests at regular intervals to
access the improvement in your health conditions. During management with
PASILOW 50 CAPSULE, avoid exposing your skin towards direct sunlight.
Wear protective loose-fitting clothes and apply sunscreen while going
outdoors.
Before taking PASILOW 50 CAPSULE inform your doctor if
you have any liver problems or any signs of infections (such as fever or
sore throat). You must also inform your doctor if you have hepatitis C
infection, fits, low blood magnesium levels, gout, alcohol dependence or
if you are about to receive any vaccinations as a precaution.
PASILOW
50 CAPSULE is not recommended for use in patients with severe
uncontrollable infections, any types of cancer or severe high blood
pressure. Do not take PASILOW 50 CAPSULE without consulting your doctor
if you are pregnant or breastfeeding.
Avoid consuming grapefruit
or drinking grapefruit juice while taking PASILOW 50 CAPSULE as it may
increase the risk of side effects. The most common side effects of
taking PASILOW 50 CAPSULE are increase in blood sugar levels, increase
in blood cholesterol levels, increased blood potassium levels, high
blood pressure, headache, loss of appetite, acne, hot flushes,
tiredness, excessive facial hair and low blood magnesium levels in
blood. Consult your doctor if any of these side effects worsen.
Uses Of PASILOW 50 CAPSULE
- Prevents graft rejection following organ transplantation
- Manage auto-immune skin diseases such as psoriasis or atopic dermatitis
- Manage rheumatoid arthritis (joint inflammation)
- Manage nephrotic syndrome (a kidney disease)
- Manage eye inflammation (such as endogenous uveitis, including Behçet’s uveitis)
How PASILOW 50 CAPSULE Works
PASILOW
50 CAPSULE is an immunosuppressive agent. It works by blocking the
release of certain chemicals in the body (such as T-cells, interleukins
and cytokines) that triggers the immune response. This action suppresses
your body’s immune functions and enables your body to accept the newly
transplanted organ. It also stops the abnormal immune response in the
body and manages your body from attacking its own cells.
How to use PASILOW 50 CAPSULE
Take
PASILOW 50 CAPSULE as directed by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine.
Your
doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and disease condition. Do not stop
taking PASILOW 50 CAPSULE without consulting your doctor.
Side Effects Of PASILOW 50 CAPSULE
Common
- high blood pressure
- headache, shakiness
- nausea, vomiting, loss of appetite, stomach pain, diarrhoea
- acne, hot flushes, fever, tiredness
- excessive facial hair
- high blood cholesterol levels
- high blood sugar levels
- tingling sensation in the body
- muscle spasm, swollen gums
- high blood levels of uric acid or potassium
- low levels of magnesium in blood
Uncommon
- lack of sleep
- oedema, weight gain
Rare
- inflammation of the pancreas, severe upper stomach pain
- menstrual irregularities, breast enlargement in men
Stop taking PASILOW 50 CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- signs of infections (such as fever or sore throat)
- signs
of brain infection called progressive multifocal leukoencephalopathy
(such as vision changes, loss of coordination, being clumsy, memory
loss, problems in speaking or understanding, muscle weakness) - brain
problems (causing seizures, confusion, disorientation, lack of
response, behavioural changes, agitation, sleeplessness, vision changes,
paralysis, stiff neck, loss of coordination with or without unusual
speech or eye movements) - swelling at the back of the eye with blurred vision
- signs of liver problems (such as yellow skin and eyes, nausea, loss of appetite and dark urine)
- low urine output, kidney problems
- low
level of red blood cells or platelets (causing pale skin, tiredness,
breathlessness, having dark urine, bruising or bleeding with no obvious
reasons, confusion, disorientation, being less alert and having kidney
problems)
How To Manage Side Effects
Nausea or vomiting:
Try
to take PASILOW 50 CAPSULE with or just after meals. Stick to simple
meals and avoid oil rich or spicy foods. Consult your doctor if nausea
worsens.
Headache:
Rest and relax. Keep
yourself hydrated by drinking plenty of fluids such as water or
electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.
Warning & Precautions
Pregnancy
PASILOW
50 CAPSULE is not recommended for use in pregnant women unless
considered necessary by the physician. Therefore, consult your doctor
before taking it.
Breastfeeding
PASILOW
50 CAPSULE may pass through the breast milk. Therefore, it is not
recommended for use in breastfeeding woman. However, consult your doctor
before taking it.
Driving and Using Machines
Do not drive or operate any heavy tools or machines if your ability is affected by PASILOW 50 CAPSULE.
Alcohol
Avoid consumption of alcohol while taking PASILOW 50 CAPSULE as it might worsen your condition.
Kidney
PASILOW
50 CAPSULE is not recommended for use in patients with other kidney
problems (except for nephrotic syndrome). Therefore, consult your doctor
before taking it.
Liver
PASILOW
50 CAPSULE should be used with caution in patients with liver problems
(including Hepatitis C infection). Therefore, consult your doctor before
taking it.
Allergy
Talk to your doctor before taking PASILOW 50 CAPSULE if you are allergic to cyclosporine.
Others
PASILOW 50 CAPSULE is not recommended for use if you:
- have severe infections in the body which is unable to control
- have any type of cancer
- have uncontrollably high blood pressure
Before taking PASILOW 50 CAPSULE inform your doctor if you:
- have any signs of infection, such as fever or sore throat
- have low levels of magnesium in the body
- have high blood potassium levels
- have gout (joint pain caused due to fluid accumulation)
- are about to receive any vaccination
- have or ever had alcohol-related problems
- have epilepsy
Use in paediatrics:
PASILOW
50 CAPSULE should only be used to manage nephrotic syndrome in
children. It is generally not recommended for managing graft rejection
or for managing other auto-immune disease condition apart from nephrotic
syndrome in children. Therefore, consult your doctor before taking it.
Use in geriatrics:
PASILOW
50 CAPSULE should be used with caution in elderly patients. Therefore,
consult your doctor before taking it. Proper dose adjustments and
careful monitoring are required in such patients.
Interactions
A. Drug – Drug interactions:
Before taking PASILOW 50 CAPSULE, inform your doctor if you are taking any of the following medicines such as:
- St. John’s Wort (an herbal medicine used to manage depression)
- dabigatran etexilate (a medicine used to manage blood clots after surgery)
- bosentan or aliskiren (medicines used to manage high blood pressure)
- vaccines
- medicines
that can increase blood potassium levels in the body (such as potassium
supplements or potassium-sparing diuretics (Ex. amiloride, triamterene
or spironolactone)) - methotrexate (a medicine used to manage cancer and severe rheumatoid arthritis)
- medicines used to manage bacterial infections (Ex. erythromycin, azithromycin, gentamycin, tobramycin, ciprofloxacin)
- medicines used to manage fungal infections (Ex. voriconazole, itraconazole, terbinafine, amphotericin B)
- medicines used for heart problems or high blood pressure (Ex. diltiazem, nicardipine, verapamil, digoxin, amiodarone)
- metoclopramide (a medicine used to stop nausea and vomiting)
- danazol (a medicine used to manage overgrowth in the uterus)
- oral contraceptives (birth control pills) Ex. ethinylestradiol
- medicines used to manage gout (Ex. colchicine, allopurinol)
- medicines used to manage gallstones (Ex. ursodiol)
- medicines used to manage leukaemia and other cancers (Ex. imatinib, melphalan, etoposide, doxorubicin)
- barbiturates (used to reduce anxiety and to induce sleep) Ex. phenobarbital
- medicines used to manage epilepsy (Ex. carbamazepine, phenytoin, cannabidiol)
- octreotide (a medicine used to manage hormonal disorder, (acromegaly) and tumours)
- orlistat (a medicine that helps in weight loss)
- ticlopidine (a medicine used to manage blood clots due to platelet aggregation)
- other medicines used to supress immune system (Ex. everolimus, sirolimus, tacrolimus)
- medicine used to reduce pain and inflammation Ex. diclofenac
- medicines used to lower cholesterol levels (Ex. fenofibrate, atorvastatin, Fluvastatin)
- medicines used to manage tuberculosis (Ex. isoniazid, rifampicin)
- medicines used to manage HIV infections (Ex. acyclovir, ritonavir, nelfinavir, saquinavir, efavirenz, etravirine, nevirapine)
- medicines
used to manage hepatitis C infection (Ex. telaprevir, boceprevir, the
combination ombitasvir/paritaprevir/ritonavir with or without dasabuvir,
elbasvir/grazoprevir and glecaprevir/pibrentasvir) - medicines used to manage gastric problems (Ex. omeprazole, cimetidine, magnesium hydroxide, aluminum hydroxide)
- trimethoprim or cotrimoxazole (used to manage bacterial infections)
- corticosteroids (used to manage allergic or autoimmune diseases) Ex. prednisolone, methylprednisolone
- medicines used to manage diabetes (Ex. repaglinide)
B. Drug – food interactions
Avoid consuming grapes or grapefruit juice while taking PASILOW 50 CAPSULE as it may increase the risk of side effects.
Overdosage:
If
you or anyone else accidentally took more PASILOW 50 CAPSULE, consult
your doctor immediately or visit the nearby hospital. Symptoms of
overdosage might include vomiting, drowsiness, headache, fast heartbeat
and kidney damage.
| Weight | 17.5 g |
|---|
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