AF 300mg Tablet 1’S
- 9%

AF 300mg Tablet 1’S

Original price was: ₹23.00.Current price is: ₹21.00.

Strictly follow the  consultation of the doctor

Country of Origin: India

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AF 300mg Tablet 1'S

Original price was: ₹23.00.Current price is: ₹21.00.

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SKU: pk/med/2210 Category:

INTRODUCTION

AF 300MG contains Fluconazole which belongs to the group of medicines called Anti-fungal agents. It is used to manage various fungal infections such as systemic candidiasis (fungal infection affecting the blood, brain, heart, eyes or other parts of the body), mucosal candidiasis (fungal infection affecting the mouth, throat or denture sore mouth), cryptococcosis (fungal infection mainly affecting the lungs and brain), vaginal candidiasis (fungal infection of the vagina and tissues at the opening of the vagina (vulva)).

Also, it prevents fungal infections in immunocompromised patients considered at risk due to HIV infection or low white blood cell count after cytotoxic chemotherapy, radiotherapy or bone marrow transplant.

Before taking AF 300MG, inform your doctor if you have liver, kidney or heart problems, abnormal levels of potassium, calcium or magnesium in your blood, are prone to develop severe skin reactions and have a history of adrenal insufficiency.

AF 300MG is not recommended for use in pregnant and breastfeeding women unless clearly advised by the doctor. AF 300MG should be used with caution in children and adolescents (from birth to 17 years of age). It should be used with caution in elderly patients particularly with renal impairment.

The most common side effects of taking AF 300MG are headache, nausea, vomiting diarrhoea, abdominal pain and indigestion. Consult your doctor if any of the side effects get worse.

USES OF AF 300MG

  • Manages various fungal infections (such as systemic candidiasis, mucosal candidiasis, cryptococcosis and vaginal candidiasis)
  • Prevents fungal infection in immunocompromised patients

HOW AF 300MG WORKS

AF 300MG works by stopping the action of an enzyme called ergosterol, which is an integral part of the fungal cell membrane to increase its cellular permeability. Thereby, making the cell membrane more permeable and stopping the fungal growth. This type of action is helpful in manageing and preventing various fungal infections.

DIRECTIONS FOR USE

Take AF 300MG as advised by your physician. Swallow AF 300MG with a glass of water and do not chew or crush the medicine. The correct dose and duration for you will be decided by the doctor depending upon your age, body weight and type of infection.

SIDE EFFECTS OF AF 300MG

COMMON

  • headache
  • nausea, vomiting
  • diarrhoea
  • abdominal pain
  • indigestion
  • acne

UNCOMMON

  • seizures, dizziness, altered nerve sensation and taste
  • skin rash with itching, abnormal odour from the skin and dry skin
  • abnormal changes in vision
  • constipation, flatulence and dry mouth
  • thirst, tiredness, body pain and fever
  • weakness, general feeling of discomfort, rigour
  • pharyngitis, herpes simplex viral infection
  • loss of appetite
  • back, muscle pain, muscle spasm
  • renal pain head spinning sensation (vertigo)
  • insomnia and nervousness
  • muscle overactivity (hypertonia)
  • increased urine output
  • abnormal or heavy vaginal bleeding, painful menses, vaginal discharge and disorder, uterine spasm, female sexual dysfunction  
  • hot flushes, excess sleepiness
  • deafness, increased blood pressure, low oxygen levels, intolerance to oral intake, inflamed and sore mouth (in children)

RARE

  • allergic reactions
  • low white blood cells and platelet count  
  • hair loss
  • damage to the liver causing liver failure, hepatitis and necrosis
  • skin reactions (like steven johnson syndrome and toxic epidermal necrolysis)
  • shaking
  • change in heart rate or rhythm

Stop taking AF 300MG and contact your doctor immediately if you experience any of the following side effects:

  • sudden wheezing, difficulty in breathing or tightness in the chest, swelling of eyelids, face or lips, itching all over the body, reddening of the skin or itchy red spots
  • skin rash that causes blistering in the mouth and tongue
  • signs of liver problems (tiredness, loss of appetite, vomiting and yellowing of the skin or whites of the eyes)
  • signs of DRESS syndrome or drug hypersensitivity syndrome (widespread rash, high body temperature and enlarged lymph nodes)

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink lot of fluids, such as water or fruit juice to keep yourself hydrated. Do not take any medicine on your own to manage diarrhoea without consulting your doctor.

Nausea or vomiting:

Stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.

Stomach pain:

Try to take rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress-free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.

Dizziness:

Lie down until the dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

AF 300MG is not recommended for use during pregnancy unless considered clearly necessary. Consult your doctor before taking AF 300MG.

BREASTFEEDING

AF 300MG is not recommended for use in breastfeeding women after repeated use or after high dose of this medicine. You may continue breast-feeding after single dose of AF 300MG. Consult your doctor before taking AF 300MG.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you experience dizziness or fits after taking AF 300MG.

KIDNEY

AF 300MG should be used with caution in patients with kidney dysfunction. Consult your doctor before taking AF 300MG.

LIVER

AF 300MG should be used with caution in patients with liver dysfunction. Consult your doctor before taking AF 300MG.

ALLERGY

AF 300MG is not recommended for use if you are allergic to fluconazole or other azole antifungals (such as itraconazole or posaconazole).

HEART DISEASE

AF 300MG should be used with caution in patients with heart rhythm problems. Consult your doctor for advice before taking AF 300MG.

OTHERS

AF 300MG is not recommended for use if you:

  • rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption

Before taking AF 300MG, inform your doctor if you:

  • have abnormal levels of potassium, calcium or magnesium in your blood
  • are prone to develop severe skin reactions (itching, reddening of the skin or difficulty in breathing)
  • have a history of adrenal insufficiency
  • have no improvement in fungal infection

Use in Pediatrics:

AF 300MG should be used with caution in children and adolescents (from birth to 17 years of age). Consult the child’s doctor for advice before administration of AF 300MG to your child.

Use in Geriatrics:  

AF 300MG should be used with caution in elderly patients particularly with renal impairment. Your doctor may adjust the dose depending upon kidney function. Consult your doctor for advice before taking AF 300MG.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking AF 300MG, inform your doctor, if you are taking any of the following medicines:

  • medicines used to manage diabetes medicines (Ex. glyburide, tolbutamide, glipizide, chlorpropamide)
  • medicines used to manage high blood pressure (Ex. hydrochlorothiazide, nifedipine, isradipine, amlodipine, felodipine and losartan)
  • medicines used as blood thinners (Ex. warfarin)
  • medicines used to use to prevent rejection of organ transplants (Ex. cyclosporine, tacrolimus, sirolimus)
  • rifampicin or rifabutin (used to manage tuberculosis)
  • astemizole, terfenadine (used to manage a certain type of allergies)
  • medicines used to control seizures /fits (Ex. phenytoin or carbamazepine)
  • theophylline (used to control asthma)
  • cisapride (used to manage heartburn)
  • medicines used to manage heart diseases (Ex. quinidine, amiodarone)
  • medicines used to manage depression (Ex. amitriptyline, nortriptyline)
  • pimozide (used to control motor or verbal tics)
  • amphotericin B, voriconazole (medicine for manageing various fungal infections)
  • erythromycin (used for manageing bacterial infections)
  • cyclophosphamide, medicines used for management of cancer (Ex. vincristine or vinblastine)
  • alfentanil, fentanyl (used as general anesthetic)
  • halofantrine (for manageing malaria)
  • medicines used to manage high cholesterol levels (Ex. atorvastatin, simvastatin and fluvastatin)
  • medicines used to manage painful conditions with inflammation (Ex. celecoxib, ibuprofen and naproxen)
  • prednisone (used to manage inflammatory disorders)
  • antiviral medications used to manage HIV infection (Ex.  saquinavir, zidovudine)
  • tofacitinib (used to manage rheumatoid arthritis)
  • ivacaftor (medicine used for manageing cystic fibrosis)
  • ibrutinib (used for manageing blood cancer)
  • midazolam, triazolam or similar medicines (used to induce sleep and manages anxiety)
  • olaparib (used for manageing ovarian cancer)
  • methadone (used to manage chronic pain and also opioid dependence)

Overdosage:

If you or anyone else accidentally takes too much of AF 300MG, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of AF 300MG are hearing, seeing, feeling and thinking things that are not real (hallucination and paranoid behaviour).

Weight 17.5 g

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