Introduction About CIPLAR 10MG TABLET
CIPLAR
10MG TABLET is used to manage hypertension (high blood pressure),
angina (chest pain) and arrhythmia (irregular heart rhythm).
It
can also be used to control abnormal increase in blood pressure and/or
heart rate caused due to various underlying conditions such as anxiety,
overactive thyroid gland, phaeochromocytoma (tumours of adrenal gland)
or Hypertrophic Subaortic Stenosis (thickening of heart muscles).
It contains Propranolol which belongs to the group of medicines called Beta blockers.
It
can also be used to manage heart attacks and migraine headaches. It
also controls shakiness of the body by blocking abnormal nerve signals
between the brain and the muscles.
Before taking CIPLAR 10MG
TABLET inform your doctor if you have any liver or kidney problems. You
must also inform your doctor if you have any other types of anginas
(unstable or Prinzmetal angina) or arrhythmia (such as
Wolf-Parkinson-White Syndrome), any breathing problems, or diabetes as a
precaution.
CIPLAR 10MG TABLET is not recommended for use in
patients with severe asthma, hypotension (low blood pressure) or shock.
It is also not suitable for use in patients with heart block, history of
heart attack or heart failure.
Do not take CIPLAR 10MG TABLET
without consulting your doctor if you are pregnant or breastfeeding. The
most common side effects of taking CIPLAR 10MG TABLET are cold fingers
and toes, slow heartbeat, tiredness, sleep disturbances and Raynaud’s
syndrome (numbness and spasm in the fingers followed by warmth and
pain). Consult your doctor if any of these side effect troubles you.
Uses Of CIPLAR 10MG TABLET
- hypertension (high blood pressure)
- angina pectoris (chest pain)
- arrhythmia (irregular heart rhythm)
- migraine (severe headache on side of the head)
- Reduce tremor (shakiness) and anxietyÂ
- Signs
and symptoms of overactive thyroid gland (such as palpitation,
nervousness, tremor, fixed stare, severe myopathy and sweating) - phaeochromocytoma (signs include high blood pressure and fast heart rate caused due to tumour of adrenal glands)
- Hypertrophic Subaortic Stenosis (signs include thickening of heart muscles causing strain on heart while pumping blood)
Benefits of CIPLAR 10MG TABLET in Hypertension:
This
medication works by reducing the workload on the heart and relaxing
blood vessels, resulting in improved blood flow and lower blood pressure
levels.
Benefits of CIPLAR 10MG TABLET in Angina pectoris:
It
reduces chest pain episodes, improves exercise tolerance by minimizing
the heart’s exertion, allowing individuals to perform daily activities
with reduced discomfort. It also helps manage stress-induced angina by
mitigating the physical effects of stress and anxiety on the heart,
providing comprehensive protection for patients with this condition.
Benefits of CIPLAR 10MG TABLET in arrhythmia:
It
helps stabilize the heart by slowing electrical signals in the heart
muscle. This action restores a regular rhythm, preventing episodes of
rapid or irregular heartbeats.
Benefits of CIPLAR 10MG TABLET in migraine:
It
helps in preventing migraines by stabilizing blood vessels, modulating
nerve activity and blood flow in the brain and reducing the triggers
that cause migraine episodes. Many users report a noticeable decline in
the frequency and severity of migraines over time.
Benefits of CIPLAR 10MG TABLET in tremor and anxiety:
It
works by blocking adrenaline’s effect on the body, which calms the
overactive signals causing tremors. It is particularly effective in
controlling physical symptoms of anxiety, such as a racing heart,
sweating, and trembling. By calming the heart rate, it helps individuals
feel more at ease in stressful situations. Blocks the body’s adrenaline
response, it allows users to remain calm and confident during
high-pressure scenarios.
How CIPLAR 10MG TABLET Works
CIPLAR
10MG TABLET is a beta-blocker. It works by blocking the actions of
certain chemical messengers (such as adrenaline and noradrenaline) in
our body that controls the function of the heart, brain and kidneys and
lungs.
In the heart, stopping the actions of these chemical
messengers reduces the heart rate and force of contraction. This helps
to control abnormal heart rate in patients suffering from arrhythmia.
It
can also reduce the risk of abnormal heart signs (such as racing
heartbeat, nervousness and high blood pressure) associated with
phaeochromocytoma or anxiety.
CIPLAR 10MG TABLET can relax the
blood vessels supplying the heart and the brain. This action improves
blood flow and oxygen supply to the heart and makes the heart to pump
blood more efficiently with less pressure. It also helps in managing and
managing problems caused due to poor blood circulation such as chest
pain (angina), heart attack or migraine.
Additionally, CIPLAR
10MG TABLET reduces the production of thyroid hormones
(triiodothyronine) in patients suffering from overactive thyroid gland.
It also stops the transfer of abnormal nerve signals between the brain
and the muscles which helps in reducing tremors.
How to use CIPLAR 10MG TABLET
Take
CIPLAR 10MG TABLET as directed by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine.
Dosage and Administration
- Follow Prescribed Dosage- it varies based on the medical condition and individual response.
- Always follow your doctor’s prescription. Do not adjust the dosage without consulting your healthcare provider.
- Common starting doses include:
                             Hypertension: 40mg twice daily.
                             Migraine Prevention: 40mg two to three times daily.
                             Anxiety: 40mg taken as needed (30-60 minutes before a stressful situation).
                             Arrhythmias: 10-40mg three to four times daily.
- It is best taken on an empty stomach or before meals for better absorption.
Missed Dosage instructions for CIPLAR 10MG TABLET:
- If
you miss a dose of CIPLAR 10MG TABLET take it as soon as you remember.
If it is almost time for your next dose, skip the missed dose. - Do not double the dose to make up for the missed one.
- Consistency
is essential, especially for chronic conditions like hypertension and
arrhythmias. Setting reminders can help ensure timely doses.
Overdosage of CIPLAR 10MG TABLET:
- Taking
more than the prescribed dose of CIPLAR 10MG TABLET can lead to serious
complications, including extremely slow heart rate (bradycardia),
difficulty breathing, low blood pressure (hypotension), seizures or loss
of consciousness. - What to Do in Case of Overdose:
Immediately seek medical attention or contact a poison control center.
Symptoms of overdose require urgent intervention, which may include
supportive measures like activated charcoal or IV fluids.
Side Effects Of CIPLAR 10MG TABLET
Like all medicines, CIPLAR 10MG TABLET may cause certain side effects, although not everybody gets them.
The most common side effects of taking CIPLAR 10MG TABLET are:
- fingers and toes may become cold
- slow heartbeat
- signs of Raynaud’s syndrome (numbness and spasm in the fingers followed by warmth and pain)
- sleep disturbances, nightmares
- fatigue (tiredness)
When to consult your doctor?
- signs
of allergic reactions (such as skin rash, swelling of the face, lips,
mouth, or throat which can lead to difficulty in breathing or
swallowing) - slow heart rate and low blood pressure causing dizziness, light-headedness, fainting or blurred vision
- worsening of existing condition
How To Manage Side Effects
Sleep Disturbances
Practicing
good sleep practices such as having a regular bedtime schedule,
avoiding naps in the daytime, limiting caffeine and TV before bedtime
can help you to sleep peacefully. If the symptom does not improve,
consult your doctor.
Tiredness
Include
whole grains, lean proteins, and fresh fruits and vegetables in your
meals. These foods help maintain steady energy levels throughout the
day. Stay hydrated, avoid heavy or processed foods. Get enough sleep,
incorporate light exercise, limit alcohol and stimulants like caffeine
Warning & Precautions
Pregnancy
Monitoring required
CIPLAR
10MG TABLET is generally not recommended for use in pregnant women
unless considered necessary by the physician, as it may harm the growing
baby. Studies in animals have reported developmental abnormalities,
including reduced fetal weight and delayed ossification, at high doses
of propranolol. Therefore, inform your doctor before taking CIPLAR 10MG
TABLET if you are pregnant, think you might be pregnant or planning to
have a baby.
Breastfeeding
Use with Caution
CIPLAR
10MG TABLET may excrete in breast milk. Limited animal data exists
specifically on the excretion of propranolol in milk, but beta-blockers
as a class are known to pass into milk. Therefore, it should be used
with caution in breastfeeding women. Consult your doctor for advice
before taking it.
Driving and Using Machines
Safe
CIPLAR
10MG TABLET is unlikely to affect your ability for driving or handling
any heavy tools or machines. However, if your experience any dizziness
or drowsiness, do not drive or handle any heavy tools or machines as a
precaution.
Alcohol
Consult your doctor
Avoid consumption of alcohol while taking CIPLAR 10MG TABLET as it might make you feel dizzier and drowsier.
Kidney
Use with Caution
CIPLAR
10MG TABLET should be used with caution in patients with kidney
problems. Therefore, consult your doctor before taking it.
Liver
Use with Caution
CIPLAR 10MG TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
Allergy
Contraindicated
Do not take CIPLAR 10MG TABLET if you are allergic to propranolol.
Lungs
Consult your doctor
CIPLAR
10MG TABLET is not recommended for use in patients suffering from
asthma. It should be used with caution in patients with other
respiratory problems (such as chronic bronchitis, emphysema, COPD or
bronchospasm). Therefore, consult your doctor before taking it.
Heart Disease
Consult your doctor
CIPLAR
10MG TABLET is not recommended for use in patients with sinus
bradycardia (slow heart beat due to problems in SA nodes), heart block,
congestive heart failure or heart defects. It should be used with
caution in patients with a previous history of heart failure or other
heart problems. Therefore, consult your doctor before taking it.
Use In Pediatrics
Consult your doctor
The
safety and effectiveness of CIPLAR 10MG TABLET have not been
established in children and adolescents (aged below 18 years).
Therefore, it should be used in children only if prescribed by the
physician.
Use In Geriatrics
Use with Caution
CIPLAR
10MG TABLET should be used with caution in elderly patients (aged above
65 years). Animal studies indicate increased sensitivity to
beta-blockers in older populations due to age-related changes in
cardiovascular physiology and drug metabolism. Therefore, consult your
doctor before taking it.
Others
CIPLAR 10MG TABLET is not recommended for use if you:
- have cardiogenic shock (heart cannot pump blood suddenly)
- have hypertensive emergency crisis (abnormal increase in blood pressure which is severe)
- have very low blood pressure
- have can increased acidity of the blood (metabolic acidosis)
- are on a strict fasting diet
- suffer from other forms of angina (Prinzmetal’s angina)
Before taking CIPLAR 10MG TABLET, inform your doctor if you:
- have diabetes
- suffer from unstable angina (chest pain that occurs in the absence of any stressful activity)
- are going for glaucoma screening test
- have muscle weakness (myasthenia gravis)
- are planning for any major surgery
- have other types of arrhythmias (such as Wolf-Parkinson-White Syndrome)
- have any bleeding problems
- have stroke or any circulatory problems
- have swollen ankles
Safety Advice
Expert advice to follow while taking CIPLAR 10MG TABLET:
- Take as prescribed and at the same time daily.
- Monitor blood pressure and heart rate regularly.
- Avoid sudden discontinuation of the medication.
- Be mindful of alcohol, smoking, and other medications.
- Protect yourself in cold weather.
- Inform your doctor about any side effects or new medications.
- Use caution during pregnancy and breastfeeding.
- Monitor blood glucose levels if diabetic.
- Visit your healthcare provider regularly for check-ups.
Interactions
A. Drug – Drug interactions:
1. Calcium Channel Blockers (e.g., Verapamil, Diltiazem)
Both
calcium channel blockers and beta-blockers like Inderal reduce heart
rate and blood pressure. When taken together, they can cause excessive bradycardia (slow heart rate) and hypotension (low blood pressure).
2. Clonidine (Alpha-2 Agonist)
Clonidine
can synergistically lower blood pressure. However, abrupt
discontinuation of clonidine while on propranolol can cause a rebound
hypertensive crisis.
3.Antiarrhythmic Drugs (e.g., Amiodarone, Sotalol)
Combining
antiarrhythmic drugs can increase the risk of heart block and severe
bradycardia, particularly in patients with pre-existing heart
conditions.
4.Antidepressants (e.g., Fluoxetine, Paroxetine)
Some
selective serotonin reuptake inhibitors (SSRIs) may increase the plasma
concentration of propranolol, potentially leading to an enhanced
beta-blocking effect and increased risk of bradycardia.
5. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) (e.g., Ibuprofen, Naproxen)
NSAIDs
may reduce the effectiveness of Inderal in controlling blood pressure
by inhibiting the production of prostaglandins, which help regulate
kidney function.
6.Insulin and Oral Hypoglycemics
Beta-blockers
like propranolol can mask the symptoms of hypoglycemia (low blood
sugar), making it harder to recognize low blood sugar levels, especially
in diabetics.
7.Monoamine Oxidase Inhibitors (MAOIs) (e.g., Phenelzine, Tranylcypromine)
The combination of MAOIs and Inderal can lead to a hypertensive crisis due to excessive catecholamine release.
8.Ergot Alkaloids (e.g., Ergotamine)
Ergotamine,
often used to treat migraines, can cause vasoconstriction, and when
combined with propranolol, it may further increase the risk of severe
hypertension or poor circulation.
Refer the drug-drug interactions of propranolol, drugs.com
Synopsis
| Drug | :Â Â | Propranolol |
| Pharmacological Category | :Â Â | Beta blockers |
| Therapeutic Indication | :Â Â | Hypertension, angina pectoris, atrial fibrillation, migraine, tremor and anxiety, thyrotoxicosis, phaeochromocytoma |
| Dosage Forms | :Â Â | Tablet, Capsule, Injection |
More Information
- Onset of Action: After
taking a 40mg tablet of propranolol by mouth, the drug typically begins
to take effect within 30 to 60 minutes. The maximum concentration of
propranolol in the blood is usually reached around 1 to 2 hours after
oral ingestion. At this point, the therapeutic effects are most
pronounced, such as a reduction in heart rate, blood pressure, and
anxiety symptoms. - Duration of Action: The effects of propranolol can last approximately 3 to 6 hours
after a single dose. Propranolol also comes in extended-release
formulations (such as Inderal LA), which can provide prolonged action,
lasting up to 24 hours.
FAQs About CIPLAR 10MG TABLET
Q: Can CIPLAR 10MG TABLET used in asthmatic patients?
A:
No, CIPLAR 10MG TABLET cannot be used in patients suffering from
asthma. This is because using it can cause breathing problems, which may
trigger an asthma attack. Always inform your doctor if you have or ever
had asthma or any kind of difficulty breathing difficulty, before
starting management with CIPLAR 10MG TABLET.
Q: Does CIPLAR 10MG TABLET make you feel sleepy?
A:
CIPLAR 10MG TABLET can occasionally cause dizziness or tiredness while
taking it. Don’t drive, use machinery, or perform any activities that
require alertness. If this occurs to you, consult your doctor for
opinion.
Q: Should we take CIPLAR 10MG TABLET before or after food?
A: CIPLAR 10MG TABLET should preferably be taken before meals. It should be swallowed with a drink of water.
Q: When can I expect relief in my symptoms after taking CIPLAR 10MG TABLET?
A:
CIPLAR 10MG TABLET usually starts working within a few hours of taking
it. However, to notice considerable changes in the symptoms of high
blood pressure or heart conditions, it may take a week. You will not be
able to notice any difference, but that does not mean it is not working.
However, keep taking CIPLAR 10MG TABLET as prescribed by your doctor to
get its full benefits.
Q: What are the uses of CIPLAR 10MG TABLET?
A:
CIPLAR 10MG TABLET It is used to manage hypertension, angina and
arrhythmia. It can also be used to manage signs and symptoms associated
with anxiety, overactive thyroid gland, phaeochromocytoma or
Hypertrophic Subaortic Stenosis. It can manage heart attacks and
migraine headaches and reduce tremors.
| Weight | 25 g |
|---|
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