Product introduction
ENDAce 40 Tablet is a medicine used for the treatment of anorexia, cachexia, or significant, unexplained weight loss in patients with advanced cancer or acquired immunodeficiency syndrome (AIDS). It helps improve appetite and promote weight gain.
ENDAce 40 Tablet may be taken with or without food. Take it exactly as prescribed by your doctor. Your doctor will decide how much you need to take and for how long. Take it regularly and at the same time each day. Do not stop taking it suddenly without your doctor’s advice.
Common side effects of ENDAce 40 Tablet include diarrhea, rash, nausea, vomiting, headache, weakness (asthenia), and high blood pressure. If any of these side effects persist or worsen, stop the medicine and inform your doctor promptly. Managing side effects may involve dose adjustments, monitoring blood sugar closely, and supportive treatment as advised by your doctor.
ENDAce 40 Tablet should not be used in patients who are allergic to megestrol acetate or any component in the product. It is contraindicated in known or suspected pregnancy because it may cause harm to the unborn baby. Women of childbearing age should use effective contraception during treatment. Nursing mothers should discontinue breastfeeding if treatment is required. Elderly patients and those with kidney problems may require careful dose selection and monitoring.
Long-term use may affect the body’s adrenal gland function and can lead to adrenal insufficiency, especially during stress such as surgery or serious illness. It may also worsen existing diabetes or cause new-onset diabetes. Caution is advised in patients with a history of blood clots, as thromboembolic events such as thrombophlebitis or pulmonary embolism have been reported.
Uses of ENDAce Tablet
- Treatment of Anorexia
- Treatment of Cachexia
- Treatment of significant unexplained Weight loss
Benefits of ENDAce Tablet
In Treatment of Anorexia
Anorexia refers to a loss of appetite or reduced desire to eat. In patients with cancer or acquired immunodeficiency syndrome (AIDS) who experience loss of appetite, ENDAce 40 Tablet helps stimulate appetite, making it easier to consume regular meals and maintain adequate calorie intake. An improved appetite can support better nutritional intake, help reduce weakness, and aid in maintaining body weight during illness.
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Side effects of ENDAce Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of ENDAce
- Nausea
- Diarrhea
- Impotence
- Rash
- Flatulence
- High blood pressure
- Weakness
How to use ENDAce Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ENDAce 40 Tablet may be taken with or without food.
How ENDAce Tablet works
ENDAce 40 Tablet is a synthetic derivative of the hormone progesterone. It is believed to act through hormonal pathways that influence appetite regulation and metabolism, leading to increased food intake and subsequent weight gain in patients with cancer- or AIDS-related anorexia, cachexia, or significant weight loss.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with ENDAce 40 Tablet. Please consult your doctor.
Pregnancy
UNSAFE
ENDAce 40 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
UNSAFE
ENDAce 40 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether ENDAce 40 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CAUTION
ENDAce 40 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of ENDAce 40 Tablet in patients with liver disease.
What if you forget to take ENDAce Tablet?
If you miss a dose of ENDAce 40 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
| Weight | 11 g |
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