Lefno 10mg Tablet 10’S
- 11%

Lefno 10mg Tablet 10’S

Original price was: ₹151.00.Current price is: ₹135.00.

*10 Tablet(s) in a Strip
* Country of Origin: India
* Delivery charges if applicable will be applied at checkout


Lefno 10mg Tablet 10'S

Original price was: ₹151.00.Current price is: ₹135.00.

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SKU: pr/med/596 Category:

Introduction About LEFNO 10MG TABLET

LEFNO
10MG TABLET contains Leflunomide which belongs to the group of
medicines called Anti-rheumatics. It is used for the management of
active rheumatoid arthritis or with active psoriatic arthritis.
Rheumatoid arthritis is an auto-immune chronic inflammatory disorder
which affects many joints including those in the hands and feet.
Symptoms include inflammation of joints, swelling, difficulty moving and
pain, loss of appetite, fever, loss of energy and anaemia (lack of red
blood cells). Active psoriatic arthritis refers to a condition where
psoriasis, a skin condition is present along with arthritis. Symptoms
include inflammation of joints, swelling, difficulty in moving, pain and
patches of red and scaly skin (skin lesions).

Before starting
management with LEFNO 10MG TABLET, your doctor might ask you to take a
few blood tests to understand the existing condition and to use this
medicine safely. LEFNO 10MG TABLET is not recommended for use in
patients having liver or moderate to severe kidney disease, any problem
which affects the immune system (like AIDS), bone marrow problems,
serious infections, severely low levels of proteins in the blood
(hypoproteinaemia) and reduced levels of white or red blood cells and
platelet count. LEFNO 10MG TABLET should be used with caution in
patients who have interstitial lung disease, tuberculosis or if you are a
male who wishes to father a child and chronic diarrhoea. Avoid
consumption of alcohol during management with this medicine as it may
increase the risk of liver damage.

LEFNO 10MG TABLET is not
recommended for use in pregnant women or women who become pregnant
during management with this medicine and it is not recommended for use
in breastfeeding women. LEFNO 10MG TABLET is not recommended for use in
children and adolescents (below 18 years of age). The most common side
effects of taking LEFNO 10MG TABLET are loss of appetite, tiredness,
headache, dizziness, diarrhoea, nausea, vomiting, inflammation of the
mouth or mouth ulcers, abdominal pain and increased hair loss. Consult
your doctor if any of the side effects worsen.

Uses Of LEFNO 10MG TABLET

It is used to manage:

  • active rheumatoid arthritis
  • active psoriatic arthritis

How LEFNO 10MG TABLET Works

LEFNO
10MG TABLET acts by inhibiting an enzyme which results in stopping the
activated and autoimmune white blood cells. This inhibition leads to
anti-inflammatory and immunomodulatory effects, reducing inflammation
due to arthritis.

How to use LEFNO 10MG TABLET

Take
LEFNO 10MG TABLET as advised by your doctor. Swallow the medicine with a
glass of water. Do not crush or chew the medicine. Your doctor will
decide the correct dose and duration for you depending upon your age,
body weight and disease condition.

Side Effects Of LEFNO 10MG TABLET

Common

  • mild allergic reactions
  • loss of appetite
  • weight loss
  • tiredness
  • headache
  • dizziness
  • abnormal skin sensations like tingling (paraesthesia)
  • mild increase in blood pressure
  • diarrhoea
  • inflammation of the colon
  • nausea
  • vomiting
  • mouth ulcers or swelling of the mouth
  • abdominal pain
  • increased hair loss
  • eczema, dry skin, rash, itching
  • tendonitis (pain in feet or hands caused by inflammation in the membrane surrounding the tendons)
  • problems affecting the nerves of the arms or legs

Uncommon

  • anxiety
  • taste disturbances
  • urticaria (nettle rash)
  • tendon rupture

Rare

  • severe increase in blood pressure
  • inflammation of the lung (interstitial lung disease)
  • hepatitis and jaundice (yellowing of the skin or white of the eyes)
  • sepsis (severe infection)

Stop taking LEFNO 10MG TABLET and contact your doctor immediately if you experience any of the following side effects:

  • serious allergic reaction (signs include weakness, light-headedness or dizziness or have difficulty breathing)
  • skin
    rash and ulcers in the mouth (Drug Reaction with Eosinophilia and
    Systematic Symptoms (DRESS), stevens-johnson syndrome and toxic
    epidermal necrolysis)
  • blood disorders (signs include pale skin, tiredness, bruising)
  • signs of liver failure (signs include tiredness, abdominal pain and jaundice)
  • signs of infection (signs include cough, fever and sore throat)
  • coughing or breathing problems (signs include interstitial lung disease or pulmonary hypertension)
  • signs of peripheral neuropathy (unusual tingling, weakness or pain in the hands or feet)

How To Manage Side Effects

Diarrhea

Drink
lot of fluids, such as water to keep yourself hydrated. Avoid eating
high-fat or spicy foods. Try to avoid taking any medicine on your own to
manage diarrhoea and consult your doctor if the symptom gets worse.

Headache

Drink
ample amount of water and avoid skipping meals. Get adequate rest. Try
to be relaxed and stress-free. Apply pain relieving balm on your
forehead if necessary. Consult your doctor if the symptom does not
improve.

Loss Of Appetite

Eat
when you feel hungry. Eat smaller meals frequently than usual. Snack
only when you’re hungry. Eat a nutritious snack which is rich in
calories and protein, such as dried fruits and nuts. Consult your doctor
if the symptom does not improve.

Nausea And Vomiting

Stick
to simple meals while taking this medicine. Avoid eating oily rich,
fried or spicy foods. Do not lie down or sleep immediately after eating.
Consult your doctor if the symptom does not improve.

Stomach Pain

Try
to rest and relax. Eat and drink slowly or try to have smaller meals
more frequently. Keep a heating pad on your stomach. If the symptom does
not improve, consult your doctor.

Warning & Precautions

Pregnancy

Contraindicated

LEFNO
10MG TABLET is not recommended for use in pregnant women or women who
become pregnant during management with this medicine, as it may increase
the risk of serious birth defects in the baby. Women of childbearing
potential should not take LEFNO 10MG TABLET without using reliable
contraceptive measures. If you plan to become pregnant after stopping
management with this medicine and it is necessary to ensure that all
traces of the medicine have left your body, this may take up to 2 years.
Consult your doctor before taking LEFNO 10MG TABLET.

Breastfeeding

Contraindicated

LEFNO
10MG TABLET is not recommended for use in breastfeeding women as it
passes through the breast milk. Consult your doctor before taking LEFNO
10MG TABLET.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy after taking LEFNO 10MG TABLET.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking LEFNO 10MG TABLET as it may increase the chances of liver damage.

Kidney

Contraindicated

LEFNO
10MG TABLET is not recommended for use in patients with moderate to
severe kidney problems. Consult your doctor before taking LEFNO 10MG
TABLET.

Liver

Contraindicated

LEFNO
10MG TABLET is not recommended for use in patients with any liver
problems. Consult your doctor before taking LEFNO 10MG TABLET.

Allergy

Contraindicated

Do not take LEFNO 10MG TABLET if you are allergic to Leflunomide or any other ingredients of this medicine.

Lungs

Use with Caution

LEFNO
10MG TABLET should be used with caution in patients who have suffered
with interstitial lung disease or if you ever had tuberculosis. Consult
your doctor before taking LEFNO 10MG TABLET.

Use In Pediatrics

Contraindicated

LEFNO
10MG TABLET is not recommended for use in children and adolescents
(below 18 years of age). Consult your child’s doctor for advice.

Others

LEFNO 10MG TABLET is not recommended for use if you:

  • have any problem which affects the immune system (like AIDS)
  • have bone marrow problems or reduced white blood or red blood cells and platelets
  • have serious infections
  • have hypoproteinaemia (severely low levels of proteins in the blood)

Before taking LEFNO 10MG TABLET, inform your doctor if you:

  • are a male who wishes to father a child
  • are due to have a specific blood test (calcium test)
  • unexplained chronic diarrhoea  

Interactions

A. Drug-Drug Interactions:

Before taking LEFNO 10MG TABLET, inform your doctor if you are taking any of the following medicines:

  • other
    medicines for rheumatoid arthritis (Ex. sulfasalazine), antimalarials
    (Ex. chloroquine and hydroxychloroquine), intramuscular or oral gold,
    D-penicillamine
  • medicines used as immunosuppressants (Ex. azathioprine, methotrexate)
  • medicines used as blood thinners (Ex. warfarin)
  • medicines used to manage multiple sclerosis (Ex. teriflunomide)
  • medicines used for the management of diabetes (repaglinide, pioglitazone, nateglinide, rosiglitazone)
  • medicines used in the management of cancer (daunorubicin, doxorubicin, paclitaxel, topotecan)
  • medicine used for depression, urinary incontinence or in kidney disease in diabetics (Ex. duloxetine)
  • medicines used for the management of severe diarrhoea (Ex alosetron)
  • medicines used to manage asthma (Ex. theophylline)
  • medicines used as a muscle relaxant (Ex. tizanidine)
  • oral contraceptives (Ex. ethinylestradiol, levonorgestrel)
  • medicines used for infections (Ex. cefaclor, benzylpenicillin, ciprofloxacin)
  • medicines used for the management of pain or inflammation (Ex. indomethacin, ketoprofen)
  • diuretics for heart disease (Ex. furosemide)
  • medicines used in the management of HIV infection (Ex. zidovudine)
  • medicines used in the management of high cholesterol (Ex. rosuvastatin, simvastatin, atorvastatin, colestyramine, pravastatin)
  • activated charcoal (used to manage certain kinds of poisoning)

Overdosage:

If
you or anyone else accidentally takes too much of LEFNO 10MG TABLET,
consult your doctor immediately or visit the nearby hospital.


Weight 17.5 g

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