- 10%
Sandimmun 50mg Injection 1ml
Original price was: ₹282.00.₹253.00Current price is: ₹253.00.
* Mkt: Novartis India Ltd
* Country of Origin: India
* Delivery charges if applicable will be applied at checkout
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Introduction About SANDIMMUN 50MG INJECTION
SANDIMMUN
50MG INJECTION contains Cyclosporine which belongs to the group of
medicines called Immunosuppressants. It is used to manage graft
rejection in patients undergoing transplantation of any organ, bone
marrow or stem cells. It can also be used to manage an ongoing graft
rejection of the newly transplanted organ.
Before receiving
SANDIMMUN 50MG INJECTION inform your doctor if you have any liver
problems or any signs of infections (such as fever or sore throat). You
must also inform your doctor if you have hepatitis C infection, fits,
low blood magnesium levels, gout, alcohol dependence or if you are about
to receive any vaccinations as a precaution.
SANDIMMUN 50MG
INJECTION is not recommended for use in patients with severe
uncontrollable infections, any types of cancer or severe high blood
pressure. Do not take SANDIMMUN 50MG INJECTION without consulting your
doctor if you are pregnant or breastfeeding
While undergoing
therapy with SANDIMMUN 50MG INJECTION your doctor will periodically
monitor your blood pressure, blood cholesterol levels, liver and kidney
functions to avoid the risk of side effects. Avoid consuming grapefruit
or drinking grapefruit juice while receiving SANDIMMUN 50MG INJECTION as
it may increase the risk of side effects.
Your doctor may also
prescribe you blood tests and urine tests at regular intervals to access
the improvement in your health conditions. During management with
SANDIMMUN 50MG INJECTION, avoid exposing your skin towards direct
sunlight. Wear protective loose-fitting clothes and apply sunscreen
while going outdoors.
The most common side effects of receiving
SANDIMMUN 50MG INJECTION are increase in blood sugar levels, increase in
blood cholesterol levels, increased blood potassium levels, high blood
pressure, headache, loss of appetite, acne, hot flushes, tiredness,
excessive facial hair and low blood magnesium levels in blood. Consult
your doctor if any of these side effects worsen.
Uses Of SANDIMMUN 50MG INJECTION
- Prevents graft rejection following organ transplantation
How SANDIMMUN 50MG INJECTION Works
SANDIMMUN
50MG INJECTION is an immunosuppressive agent. It works by blocking the
release of certain chemicals in the body (such as T-cells, interleukins
and cytokines) that triggers the immune response. This action suppresses
your body’s immune functions and enables your body to accept the
transplanted organ. As a result, it manages the risk of graft rejection
and increases the survival of the newly transplanted organ.
How to use SANDIMMUN 50MG INJECTION
SANDIMMUN 50MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously).
Your
doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and disease condition. Do not stop
receiving SANDIMMUN 50MG INJECTION without consulting your doctor.
Side Effects Of SANDIMMUN 50MG INJECTION
Common
- high blood pressure
- headache, shakiness
- nausea, vomiting, loss of appetite, stomach pain, diarrhoea
- acne, hot flushes, fever, tiredness
- excessive facial hair
- high blood cholesterol levels
- high blood sugar levels
- tingling sensation in the body
- muscle spasm, swollen gums
- high blood levels of uric acid or potassium
- low levels of magnesium in blood
Uncommon
- lack of sleep
- oedema, weight gain
Rare
- inflammation of the pancreas, severe upper stomach pain
- menstrual irregularities, breast enlargement in men
Contact
your doctor immediately if you experience any of the following side
effects while or after receiving SANDIMMUN 50MG INJECTION:
- signs of infections (such as fever or sore throat)
- signs
of brain infection called progressive multifocal leukoencephalopathy
(such as vision changes, loss of coordination, being clumsy, memory
loss, problems in speaking or understanding, muscle weakness) - brain
problems (causing seizures, confusion, disorientation, lack of
response, behavioural changes, agitation, sleeplessness, vision changes,
paralysis, stiff neck, loss of coordination with or without unusual
speech or eye movements) - swelling at the back of the eye with blurred vision
- signs of liver problems (such as yellow skin and eyes, nausea, loss of appetite and dark urine)
- low urine output, kidney problems
- low
level of red blood cells or platelets (causing pale skin, tiredness,
breathlessness, having dark urine, bruising or bleeding with no obvious
reasons, confusion, disorientation, being less alert and having kidney
problems)
How To Manage Side Effects
Nausea or vomiting:
Stick to simple meals and avoid oil rich or spicy foods. Consult your doctor if nausea worsens.
Headache: Â
Rest
and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead
can be beneficial. Do not consume excessive alcohol, as it could
aggravate your headache. Consult your doctor if your headache worsens.
Warning & Precautions
Pregnancy
SANDIMMUN
50MG INJECTION is not recommended for use in pregnant women unless
considered necessary by the physician. Therefore, consult your doctor
before receiving it.
Breastfeeding
SANDIMMUN
50MG INJECTION may pass through the breast milk. Therefore, it is not
recommended for use in breastfeeding woman. However, consult your doctor
before receiving it.
Driving and Using Machines
Do not drive or operate any heavy tools or machines if your ability is affected by SANDIMMUN 50MG INJECTION.
Alcohol
Avoid consumption of alcohol while receiving SANDIMMUN 50MG INJECTION as it might worsen your condition.
Kidney
SANDIMMUN
50MG INJECTION is not recommended for use in patients with other kidney
problems (except for nephrotic syndrome). Therefore, consult your
doctor before receiving it.
Liver
SANDIMMUN
50MG INJECTION should be used with caution in patients with liver
problems (including Hepatitis C infection). Therefore, consult your
doctor before receiving it.
Allergy
Talk to your doctor before receiving SANDIMMUN 50MG INJECTION if you are allergic to cyclosporine.
Others
SANDIMMUN 50MG INJECTION is not recommended for use if you:
- have severe infections in the body which is unable to control
- have any type of cancer
- have uncontrollably high blood pressure
Before receiving SANDIMMUN 50MG INJECTION inform your doctor if you:
- have any signs of infection, such as fever or sore throat
- have low levels of magnesium in the body
- have high blood potassium levels
- have gout (joint pain caused due to fluid accumulation)
- are about to receive any vaccination
- have or ever had alcohol-related problems
- have epilepsy
Use in paediatrics:
The
safety and effectiveness of SANDIMMUN 50MG INJECTION have not been
established in children and adolescents (aged below 18 years).
Therefore, consult your doctor before receiving it.
Use in geriatrics:
SANDIMMUN
50MG INJECTION should be used with caution in elderly patients.
Therefore, consult your doctor before receiving it. Proper dose
adjustments and careful monitoring are required in such patients.
Interactions
A. Drug – Drug interactions:
Before receiving SANDIMMUN 50MG INJECTION, inform your doctor if you are taking any of the following medicines such as:
- St. John’s Wort (an herbal medicine used to manage depression)
- dabigatran etexilate (a medicine used to manage blood clots after surgery)
- bosentan or aliskiren (medicines used to manage high blood pressure)
- vaccines
- medicines
that can increase blood potassium levels in the body (such as potassium
supplements or potassium-sparing diuretics (Ex. amiloride, triamterene
or spironolactone)) - methotrexate (a medicine used to manage cancer and severe rheumatoid arthritis)
- medicines used to manage bacterial infections (Ex. erythromycin, azithromycin, gentamycin, tobramycin, ciprofloxacin)
- medicines used to manage fungal infections (Ex. voriconazole, itraconazole, terbinafine, amphotericin B)
- medicines used for heart problems or high blood pressure (Ex. diltiazem, nicardipine, verapamil, digoxin, amiodarone)
- metoclopramide (a medicine used to stop nausea and vomiting)
- danazol (a medicine used to manage overgrowth in the uterus)
- oral contraceptives (birth control pills) Ex. ethinylestradiol
- medicines used to manage gout (Ex. colchicine, allopurinol)
- medicines used to manage gallstones (Ex. ursodiol)
- medicines used to manage leukaemia and other cancers (Ex. imatinib, melphalan, etoposide, doxorubicin)
- barbiturates (used to reduce anxiety and to induce sleep) Ex. phenobarbital
- medicines used to manage epilepsy (Ex. carbamazepine, phenytoin, cannabidiol)
- octreotide (a medicine used to manage hormonal disorder, (acromegaly) and tumours)
- orlistat (a medicine that helps in weight loss)
- ticlopidine (a medicine used to manage blood clots due to platelet aggregation)
- other medicines used to supress immune system (Ex. everolimus, sirolimus, tacrolimus)
- medicine used to reduce pain and inflammation Ex. diclofenac
- medicines used to lower cholesterol levels (Ex. fenofibrate, atorvastatin, Fluvastatin)
- medicines used to manage tuberculosis (Ex. isoniazid, rifampicin)
- medicines used to manage HIV infections (Ex. acyclovir, ritonavir, nelfinavir, saquinavir, efavirenz, etravirine, nevirapine)
- medicines
used to manage hepatitis C infection (Ex. telaprevir, boceprevir, the
combination ombitasvir/paritaprevir/ritonavir with or without dasabuvir,
elbasvir/grazoprevir and glecaprevir/pibrentasvir) - medicines used to manage gastric problems (Ex. omeprazole, cimetidine, magnesium hydroxide, aluminum hydroxide)
- trimethoprim or cotrimoxazole (used to manage bacterial infections)
- corticosteroids (used to manage allergic or autoimmune diseases) Ex. prednisolone, methylprednisolone
- medicines used to manage diabetes (Ex. repaglinide)
B. Drug – food interactions
Avoid consuming grapes or grapefruit juice while receiving SANDIMMUN 50MG INJECTION as it may increase the risk of side effects.
Overdosage:
SANDIMMUN
50MG INJECTION will be administered to you only by a doctor or a nurse
in a hospital, and so it is unlikely to receive an overdose. However,
consult your doctor if you experience any unusual side effects.
| Weight | 10 g |
|---|
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