SANDIMMUN NEORAL Oral Solution 50ml
- 10%

SANDIMMUN NEORAL Oral Solution 50ml

Original price was: ₹4,230.00.Current price is: ₹3,807.00.

* Mkt: Novartis India Ltd

* Country of Origin: India

* Delivery charges if applicable will be applied at checkout

SANDIMMUN NEORAL Oral Solution 50ml

Original price was: ₹4,230.00.Current price is: ₹3,807.00.

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Introduction About SANDIMMUN NEORAL ORAL SOLUTION

SANDIMMUN
NEORAL ORAL SOLUTION contains Cyclosporine which belongs to the group
of medicines called Immunosuppressants. It is used to manage graft
rejection in patients undergoing transplantation of any organ, bone
marrow or stem cells.

It can also be used to manage various
auto-immune disease conditions such as psoriasis, atopic dermatitis (or
eczema), rheumatoid arthritis (joint inflammation) or nephrotic syndrome
(a kidney disease). It is mostly used in combination with other immune
suppressants (such as azathioprine) to achieve maximum benefits.

Take
SANDIMMUN NEORAL ORAL SOLUTION regularly as instructed by your doctor.
While undergoing therapy with SANDIMMUN NEORAL ORAL SOLUTION your doctor
will periodically monitor your blood pressure, blood cholesterol
levels, liver and kidney functions to avoid the risk of side effects.

Your
doctor may also prescribe you blood tests and urine tests at regular
intervals to access the improvement in your health conditions. During
management with SANDIMMUN NEORAL ORAL SOLUTION, avoid exposing your skin
towards direct sunlight. Wear protective loose-fitting clothes and
apply sunscreen while going outdoors.

Before taking SANDIMMUN
NEORAL ORAL SOLUTION inform your doctor if you have any liver problems
or any signs of infections (such as fever or sore throat). You must also
inform your doctor if you have hepatitis C infection, fits, low blood
magnesium levels, gout, alcohol dependence or if you are about to
receive any vaccinations as a precaution.

SANDIMMUN NEORAL ORAL
SOLUTION is not recommended for use in patients with severe
uncontrollable infections, any types of cancer or severe high blood
pressure. Do not take SANDIMMUN NEORAL ORAL SOLUTION without consulting
your doctor if you are pregnant or breastfeeding.

Avoid consuming
grapefruit or drinking grapefruit juice while taking SANDIMMUN NEORAL
ORAL SOLUTION as it may increase the risk of side effects.

The
most common side effects of taking SANDIMMUN NEORAL ORAL SOLUTION are
increase in blood sugar levels, increase in blood cholesterol levels,
increased blood potassium levels, high blood pressure, headache, loss of
appetite, acne, hot flushes, tiredness, excessive facial hair and low
blood magnesium levels in blood. Consult your doctor if any of these
side effects worsen.

Uses Of SANDIMMUN NEORAL ORAL SOLUTION

  • Prevents graft rejection following organ transplantation
  • Manage auto-immune skin diseases such as psoriasis or atopic dermatitis
  • Manage rheumatoid arthritis (joint inflammation)
  • Manage nephrotic syndrome (a kidney disease)

How SANDIMMUN NEORAL ORAL SOLUTION Works

SANDIMMUN
NEORAL ORAL SOLUTION is an immunosuppressive agent. It works by
blocking the release of certain chemicals in the body (such as T-cells,
interleukins and cytokines) that triggers the immune response. This
action suppresses your body’s immune functions and enables your body to
accept the newly transplanted organ. It also stops the abnormal immune
response in the body and manages your body from attacking its own cells.

How to use SANDIMMUN NEORAL ORAL SOLUTION

Take
SANDIMMUN NEORAL ORAL SOLUTION as directed by your physician. Shake
well before use. Measure the required amount of the medicine in the
measuring cup provided with the pack. Consume the medicine orally after
measuring.

Your doctor will decide the correct dose and duration
of therapy for you depending upon your age, body weight and disease
condition. Do not stop taking SANDIMMUN NEORAL ORAL SOLUTION without
consulting your doctor.

Side Effects Of SANDIMMUN NEORAL ORAL SOLUTION

Common

  • high blood pressure
  • headache, shakiness
  • nausea, vomiting, loss of appetite, stomach pain, diarrhoea
  • acne, hot flushes, fever, tiredness
  • excessive facial hair
  • high blood cholesterol levels
  • high blood sugar levels
  • tingling sensation in the body
  • muscle spasm, swollen gums
  • high blood levels of uric acid or potassium
  • low levels of magnesium in blood

Uncommon

  • lack of sleep
  • oedema, weight gain

Rare

  • inflammation of the pancreas, severe upper stomach pain
  • menstrual irregularities, breast enlargement in men

Stop
taking SANDIMMUN NEORAL ORAL SOLUTION and contact your doctor
immediately if you experience any of the following side effects:

  • signs of infections (such as fever or sore throat)
  • signs
    of brain infection called progressive multifocal leukoencephalopathy
    (such as vision changes, loss of coordination, being clumsy, memory
    loss, problems in speaking or understanding, muscle weakness)
  • brain
    problems (causing seizures, confusion, disorientation, lack of
    response, behavioural changes, agitation, sleeplessness, vision changes,
    paralysis, stiff neck, loss of coordination with or without unusual
    speech or eye movements)
  • swelling at the back of the eye with blurred vision
  • signs of liver problems (such as yellow skin and eyes, nausea, loss of appetite and dark urine)
  • low urine output, kidney problems
  • low
    level of red blood cells or platelets (causing pale skin, tiredness,
    breathlessness, having dark urine, bruising or bleeding with no obvious
    reasons, confusion, disorientation, being less alert and having kidney
    problems)

How To Manage Side Effects

Nausea or vomiting:

Try
to take SANDIMMUN NEORAL ORAL SOLUTION with or just after meals. Stick
to simple meals and avoid oil rich or spicy foods. Consult your doctor
if nausea worsens.

Headache:  

Rest and
relax. Keep yourself hydrated by drinking plenty of fluids such as water
or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate
your headache. Consult your doctor if your headache worsens.

Warning & Precautions

Pregnancy

SANDIMMUN
NEORAL ORAL SOLUTION is not recommended for use in pregnant women
unless considered necessary by the physician. Therefore, consult your
doctor before taking it. Women of childbearing potential must use a
suitable contraceptive method to avoid pregnancy while taking SANDIMMUN
NEORAL ORAL SOLUTION.

Breastfeeding

SANDIMMUN
NEORAL ORAL SOLUTION may pass through the breast milk. Therefore, it is
not recommended for use in breastfeeding woman. However, consult your
doctor before taking it.

Driving and Using Machines

Do not drive or operate any heavy tools or machines if your ability is affected by SANDIMMUN NEORAL ORAL SOLUTION.

Alcohol

Avoid consumption of alcohol while taking SANDIMMUN NEORAL ORAL SOLUTION as it might worsen your condition.

Kidney

SANDIMMUN
NEORAL ORAL SOLUTION is not recommended for use in patients with other
kidney problems (except for nephrotic syndrome). Therefore, consult your
doctor before taking it.

Liver

SANDIMMUN
NEORAL ORAL SOLUTION should be used with caution in patients with liver
problems (including Hepatitis C infection). Therefore, consult your
doctor before taking it.

Allergy

Talk to your doctor before taking SANDIMMUN NEORAL ORAL SOLUTION if you are allergic to cyclosporine.

Others

SANDIMMUN NEORAL ORAL SOLUTION is not recommended for use if you:

  • have severe infections in the body which is unable to control
  • have any type of cancer
  • have uncontrollably high blood pressure

Before taking SANDIMMUN NEORAL ORAL SOLUTION inform your doctor if you:

  • have any signs of infection, such as fever or sore throat
  • have low levels of magnesium in the body
  • have high blood potassium levels
  • have gout (joint pain caused due to fluid accumulation)
  • are about to receive any vaccination
  • have or ever had alcohol-related problems
  • have epilepsy

Use in paediatrics:

SANDIMMUN
NEORAL ORAL SOLUTION should only be used to manage nephrotic syndrome
in children. It is generally not recommended for managing graft
rejection or for managing other auto-immune disease condition apart from
nephrotic syndrome in children. Therefore, consult your doctor before
taking it.

Use in geriatrics:

SANDIMMUN
NEORAL ORAL SOLUTION should be used with caution in elderly patients.
Therefore, consult your doctor before taking it. Proper dose adjustments
and careful monitoring are required in such patients.

Interactions

A. Drug – Drug interactions:

Before taking SANDIMMUN NEORAL ORAL SOLUTION, inform your doctor if you are taking any of the following medicines such as:

  • St. John’s Wort (an herbal medicine used to manage depression)
  • dabigatran etexilate (a medicine used to manage blood clots after surgery)
  • bosentan or aliskiren (medicines used to manage high blood pressure)
  • vaccines
  • medicines
    that can increase blood potassium levels in the body (such as potassium
    supplements or potassium-sparing diuretics (Ex. amiloride, triamterene
    or spironolactone))
  • methotrexate (a medicine used to manage cancer and severe rheumatoid arthritis)
  • medicines used to manage bacterial infections (Ex. erythromycin, azithromycin, gentamycin, tobramycin, ciprofloxacin)
  • medicines used to manage fungal infections (Ex. voriconazole, itraconazole, terbinafine, amphotericin B)
  • medicines used for heart problems or high blood pressure (Ex. diltiazem, nicardipine, verapamil, digoxin, amiodarone)
  • metoclopramide (a medicine used to stop nausea and vomiting)
  • danazol (a medicine used to manage overgrowth in the uterus)
  • oral contraceptives (birth control pills) Ex. ethinylestradiol
  • medicines used to manage gout (Ex. colchicine, allopurinol)
  • medicines used to manage gallstones (Ex. ursodiol)
  • medicines used to manage leukaemia and other cancers (Ex. imatinib, melphalan, etoposide, doxorubicin)
  • barbiturates (used to reduce anxiety and to induce sleep) Ex. phenobarbital
  • medicines used to manage epilepsy (Ex. carbamazepine, phenytoin, cannabidiol)
  • octreotide (a medicine used to manage hormonal disorder, (acromegaly) and tumours)
  • orlistat (a medicine that helps in weight loss)
  • ticlopidine (a medicine used to manage blood clots due to platelet aggregation)
  • other medicines used to supress immune system (Ex. everolimus, sirolimus, tacrolimus)
  • medicine used to reduce pain and inflammation Ex. diclofenac
  • medicines used to lower cholesterol levels (Ex. fenofibrate, atorvastatin, Fluvastatin)
  • medicines used to manage tuberculosis (Ex. isoniazid, rifampicin)
  • medicines used to manage HIV infections (Ex. acyclovir, ritonavir, nelfinavir, saquinavir, efavirenz, etravirine, nevirapine)
  • medicines
    used to manage hepatitis C infection (Ex. telaprevir, boceprevir, the
    combination ombitasvir/paritaprevir/ritonavir with or without dasabuvir,
    elbasvir/grazoprevir and glecaprevir/pibrentasvir)
  • medicines used to manage gastric problems (Ex. omeprazole, cimetidine, magnesium hydroxide, aluminum hydroxide)
  • trimethoprim or cotrimoxazole (used to manage bacterial infections)
  • corticosteroids (used to manage allergic or autoimmune diseases) Ex. prednisolone, methylprednisolone
  • medicines used to manage diabetes (Ex. repaglinide)

B. Drug – food interactions

Avoid
consuming grapes or grapefruit juice while taking SANDIMMUN NEORAL ORAL
SOLUTION as it may increase the risk of side effects.

Overdosage:

If
you or anyone else accidentally took more SANDIMMUN NEORAL ORAL
SOLUTION, consult your doctor immediately or visit the nearby hospital.
Symptoms of overdosage might include vomiting, drowsiness, headache,
fast heartbeat and kidney damage.

Weight 75 g

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