Syscan 150mg Capsule 1’S
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Syscan 150mg Capsule 1’S

Original price was: ₹21.51.Current price is: ₹20.56.

*1 Capsule(s) in a Strip * Mkt: Torrent Pharmaceuticals Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout
Syscan 150mg Capsule 1'S

Original price was: ₹21.51.Current price is: ₹20.56.

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INTRODUCTION ABOUT SYSCAN 150MG CAPSULE

SYSCAN
150MG CAPSULE contains Fluconazole which belongs to the group of
medicines called Anti-fungal agents. It is used to manage various fungal
infections such as systemic candidiasis (fungal infection affecting the
blood, brain, heart, eyes or other parts of the body), mucosal
candidiasis (fungal infection affecting the mouth, throat or denture
sore mouth), cryptococcosis (fungal infection mainly affecting the lungs
and brain), vaginal candidiasis (fungal infection of the vagina and
tissues at the opening of vagina (vulva)).

Also, it manages
fungal infections in immunocompromised patients considered at risk as a
consequence of HIV infection or low white blood cell count after
cytotoxic chemotherapy, radiotherapy or bone marrow transplant.  

Before
taking SYSCAN 150MG CAPSULE, inform your doctor if you have liver,
kidney or heart problems, abnormal levels of potassium, calcium, or
magnesium in your blood, are prone to develop severe skin reactions and
have a history of adrenal insufficiency.  

SYSCAN 150MG CAPSULE
is not recommended for use in pregnant and breast-feeding women unless
clearly advised by the doctor. SYSCAN 150MG CAPSULE should be used with
caution in children and adolescents (from birth to 17 years of age). It
should be used with caution in elderly patients particularly with renal
impairment.

The most common side effects of taking SYSCAN 150MG
CAPSULE are headache, nausea, vomiting diarrhea, abdominal pain, and
indigestion. Consult your doctor if any of the side effect gets worse.

USES OF SYSCAN 150MG CAPSULE

  • Manage various fungal infections (such as systemic candidiasis, mucosal candidiasis, cryptococcosis and vaginal candidiasis)  
  • Prevents fungal infection in immunocompromised patients

HOW SYSCAN 150MG CAPSULE WORKS

SYSCAN
150MG CAPSULE works by stopping the action of an enzyme called
ergosterol, which is an integral part of the fungal cell membrane to
increase its cellular permeability. Thereby, making the cell membrane
more permeable and stops the fungal growth. This type of action is
useful in managing and managing various fungal infections.

DIRECTIONS FOR USE

Take
SYSCAN 150MG CAPSULE as advised by your physician. Swallow SYSCAN 150MG
CAPSULE with a glass of water and do not chew or crush the medicine.
The correct dose and duration for you will be decide by the doctor
depending upon your age, body weight and type of infection.

SIDE EFFECTS OF SYSCAN 150MG CAPSULE

COMMON

  • headache
  • nausea, vomiting
  • diarrhea
  • abdominal pain
  • indigestion
  • acne

UNCOMMON

  • seizures, dizziness, altered nerve sensation and taste
  • skin rash with itching, abnormal odor from skin and dry skin
  • abnormal changes in vision
  • constipation, flatulence and dry mouth
  • thirst, tiredness, body pain and fever
  • weakness, general feeling of discomfort, rigor
  • pharyngitis, herpes simplex viral infection
  • loss of appetite
  • back, muscle pain, muscle spasm
  • renal pain
  • head spinning sensation (vertigo)
  • insomnia, and nervousness
  • muscle overactivity (hypertonia)
  • increased urine output
  • abnormal or heavy vaginal bleeding, painful menses, vaginal discharge and disorder, uterine spasm, female sexual dysfunction  
  • hot flushes, excess sleepiness
  • deafness, increased blood pressure, low oxygen levels, intolerance to oral intake, inflamed and sore mouth (in children)

RARE

  • allergic reactions
  • low white blood cells and platelet count  
  • hair loss
  • damage to liver causing liver failure, hepatitis, and necrosis
  • skin reactions (like steven johnson syndrome and toxic epidermal necrolysis)
  • shaking
  • change in heart rate or rhythm

Stop taking SYSCAN 150MG CAPSULE and contact your doctor immediately if you experience any of the following side effects:

  • sudden
    wheezing, difficulty in breathing or tightness in the chest, swelling
    of eyelids, face or lips, itching all over the body, reddening of the
    skin or itchy red spots
  • skin rash that causes blistering in mouth and tongue
  • signs of liver problems (tiredness, loss of appetite, vomiting and yellowing of the skin or whites of the eyes)
  • signs of DRESS syndrome or drug hypersensitivity syndrome (widespread rash, high body temperature and enlarged lymph nodes)

HOW TO MANAGE SIDE EFFECTS

Diarrhea:

Drink
lot of fluids, such as water or fruit juice to keep yourself hydrated.
Do not take any medicine on your own to manage diarrhea without
consulting your doctor.

Nausea or vomiting:

Stick
to simple meals while receiving this medicine. Avoid eating oily rich,
fried or spicy foods. Do not lie down or sleep immediately after eating.
Consult your doctor if the symptom does not improve.

Stomach pain:

Try
to take rest and relax. Eat and drink slowly or try to have smaller and
frequent meals. Keep a heat pad on your stomach. If the symptom does
not improve, contact your doctor.

Headache:

Drink
ample amount of water and avoid skipping meals. Get adequate rest. Try
to be relaxed and stress free. Apply pain relieving balm on your
forehead if necessary. Consult your doctor if the symptom does not
improve.   

Dizziness:

Lie down until
dizziness is gone, then get up slowly. Move slowly and carefully, do not
hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid
coffee, cigarettes, alcohol, and drugs. Consult your doctor if the
symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

SYSCAN
150MG CAPSULE is not recommended for use during pregnancy unless
considered clearly necessary. Consult your doctor before taking SYSCAN
150MG CAPSULE.

BREASTFEEDING

SYSCAN
150MG CAPSULE is not recommended for use in breastfeeding women after
repeated use or after high dose of this medicine. You may continue
breast-feeding after single dose of SYSCAN 150MG CAPSULE. Consult your
doctor before taking SYSCAN 150MG CAPSULE.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you experience dizziness or fits after taking SYSCAN 150MG CAPSULE.

KIDNEY

SYSCAN
150MG CAPSULE should be used with caution in patients with kidney
dysfunction. Consult your doctor before taking SYSCAN 150MG CAPSULE.

LIVER

SYSCAN
150MG CAPSULE should be used with caution in patients with liver
dysfunction. Consult your doctor before taking SYSCAN 150MG CAPSULE.

ALLERGY

SYSCAN
150MG CAPSULE is not recommended for use if you are allergic to
fluconazole or other azole anti-fungals (such as itraconazole or
posaconazole).

HEART DISEASE

SYSCAN
150MG CAPSULE should be used with caution in patients with heart rhythm
problems. Consult your doctor for advice before taking SYSCAN 150MG
CAPSULE.

OTHERS

SYSCAN 150MG CAPSULE is not recommended for use if you:

  • rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption

Before taking SYSCAN 150MG CAPSULE, inform your doctor if you:

  • have abnormal levels of potassium, calcium, or magnesium in your blood
  • are prone to develop severe skin reactions (itching, reddening of the skin or difficulty in breathing)
  • have history of adrenal insufficiency
  • have no improvement in fungal infection

Use in Pediatrics:

SYSCAN
150MG CAPSULE should be used with caution in children and adolescents
(from birth to 17 years of age). Consult child’s doctor for advice
before administration of SYSCAN 150MG CAPSULE to your child.

Use in Geriatrics:  

SYSCAN
150MG CAPSULE should be used with caution in elderly patients
particularly with renal impairment. Your doctor may adjust the dose
depending upon kidney function. Consult your doctor for advice before
taking SYSCAN 150MG CAPSULE.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking SYSCAN 150MG CAPSULE, inform your doctor, if you are taking any of the following medicines:

  • medicines used to manage diabetes medicines (Ex. glyburide, tolbutamide, glipizide, chlorpropamide)
  • medicines
    used to manage high blood pressure (Ex. hydrochlorothiazide,
    nifedipine, isradipine, amlodipine, felodipine and losartan)
  • medicines used as blood thinners (Ex. warfarin)
  • medicines used to use to manage rejection of organ transplants (Ex. cyclosporine, tacrolimus, sirolimus)
  • rifampicin or rifabutin (used to manage tuberculosis)
  • astemizole, terfenadine (used to manage certain type of allergies)
  • medicines used to control seizures /fits (Ex. phenytoin or carbamazepine)
  • theophylline (used to control asthma)
  • cisapride (used to manage heartburn)
  • medicines used to manage heart diseases (Ex. quinidine, amiodarone)
  • medicines used to manage depression (Ex. amitriptyline, nortriptyline)
  • pimozide (used to control motor or verbal tics)
  • amphotericin B, voriconazole (medicine for managing various fungal infections)
  • erythromycin (used for managing bacterial infections)
  • cyclosphosphamide, medicines used for management of cancer (Ex. vincristine or vinblastine)
  • alfentanil, fentanyl (used as general anesthetic)
  • halofantrine (for managing malaria)
  • medicines used to manage high cholesterol levels (Ex. atorvastatin, simvastatin, and fluvastatin)
  • medicines used to manage painful conditions with inflammation (Ex. celecoxib, ibuprofen, and naproxen)
  • prednisone (used to manage inflammatory disorders)
  • antiviral medications used to manage HIV infection (Ex.  saquinavir, zidovudine)
  • tofacitinib (used to manage rheumatoid arthritis)
  • ivacaftor (medicine used for managing cystic fibrosis)
  • ibrutinib (used for managing blood cancer)
  • midazolam, triazolam or similar medicines (used to induce sleep and manages anxiety)
  • olaparib (used for managing ovarian cancer)
  • methadone (used to manage chronic pain and also opioid dependance)

Overdosage:

If
you or anyone else accidentally takes too much of SYSCAN 150MG CAPSULE,
consult your doctor immediately or visit the nearby hospital.
Overdosage symptoms of SYSCAN 150MG CAPSULE are hearing, seeing, feeling
and thinking things that are not real (hallucination and paranoid
behaviour).

SYNOPSIS

Drug :   Fluconazole
Pharmacological Category :   Triazoles
Therapeutic Indication :   Prevent and manages various fungal infections
Dosage Forms :   Tablet, Dispersible tablet, Capsule, Injection, Infusion, Dry syrup, Dusting powder, Gel, Cream, Ear drops, Eye drops, Soap

MORE INFORMATION

  • Keep SYSCAN 150MG CAPSULE out of reach of children
  • Store at room temperature

FAQs ABOUT SYSCAN 150MG CAPSULE

How does SYSCAN 150MG CAPSULE work?

SYSCAN
150MG CAPSULE works by stopping the action of an enzyme called
ergosterol, which is an integral part of the fungal cell membrane to
increase its cellular permeability. Thereby, making the cell membrane
more permeable and stops the fungal growth. This type of action is
useful in managing and managing various fungal infections.

What if I forget to take a dose of SYSCAN 150MG CAPSULE?

If
you have missed a dose of SYSCAN 150MG CAPSULE, take it as soon as you
remember. However, if it is almost time for your next dose, skip the
missed dose and take the next scheduled dose. Do not double the dose of
SYSCAN 150MG CAPSULE to make up for the missed one as this may increase
the chances of developing side effects.

What are the common side effects of SYSCAN 150MG CAPSULE?

The
common side effects of taking SYSCAN 150MG CAPSULE are headache,
nausea, vomiting, diarrhea, abdominal pain, indigestion and acne.
Consult your doctor if any of the symptom gets worse or does not improve
over the time

Can SYSCAN 150MG CAPSULE be used in elderly patients?

SYSCAN
150MG CAPSULE should be used with caution in elderly patients
particularly with renal impairment. Your doctor may adjust the dose
depending upon kidney function. Consult your doctor for advice before
taking SYSCAN 150MG CAPSULE.

Is SYSCAN 150MG CAPSULE safe to use during pregnancy?

SYSCAN
150MG CAPSULE is not recommended for use during pregnancy unless
clearly advised by the doctor. Consult your doctor before taking SYSCAN
150MG CAPSULE if you are pregnant or planning to get pregnant.

REFERENCES

1. KD. Tripathi. Section, Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 787.

2.
Ameish Govindarajan; Karlyle G. Bistas; Curtis J. Ingold; Ayham Aboeed.
NIH National Library of Medicine, National center for biotechnology
information. June 2022. [Accessed on 12th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK537158

3.
Josilene Chaves Ruela Corrra & Herida Regina Nunes Salgado. Review
of Fluconazole Properties and Analytical Methods for Its Determination,
Critical Reviews in Analytical Chemistry. May 2011. [Accessed on 12th
July 2022] https://www.tandfonline.com/doi/abs/10.1080/10408347.2011.557980?journalCode=batc20

3. Viatris Ltd. Fluconazole. [Revised in March 2022] [Accessed on 12th July 2022] https://www.medsafe.govt.nz/profs/datasheet/f/fluconazolecapmylan.pdf

4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed on 12th July 2022] https://www.medicines.org.uk/emc/files/pil.6086.pdf

5. FDC limited. Zocon (Fluconazole tablets) [Revised in July 2022] [Accessed on 12th July 2022] http://fdcindia.com/PackageInsert/ZoconTablets.pdf

USEFUL DIAGNOSTIC TESTS

  • Complete blood count
  • Liver function test
Weight 10 g

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