Introduction About TRIVEDON MR TABLET
TRIVEDON
MR TABLET contains Trimetazidine, which belongs to the group of
medicines called Anti-anginal agents. It is used in adult patients for
the management of angina pectoris (chest pain caused by a heart disease)
along with other medicines. It protects the heart cells from the
effects of a reduced oxygen supply during an episode of angina.
Angina
is a type of chest pain caused by reduced blood flow to the heart. It
is a symptom of an underlying coronary heart disease (narrowing or
blockage of blood vessels that carry blood and oxygen to the heart). It
is characterized by sudden, sharp, and severe pain, pressure, or
discomfort in the chest radiating to the left shoulder. The discomfort
can also be felt in the jaw, neck, back, or abdomen. Some people may
also suffer from shortness of breath or fatigue.
TRIVEDON MR
TABLET is not recommended for use if you have Parkinson disease (a brain
disorder that affects movement (trembling, rigid posture, slow
movements, and a shuffling, unbalanced walk)) or severe kidney problems.
This
medicine should be used cautiously in elderly patients (above 75
years), pregnant, and breast-feeding mothers. Do not drive or operate
any machinery if you feel dizzy after taking TRIVEDON MR TABLET.
The
common side effects associated with TRIVEDON MR TABLET are dizziness,
headache, abdominal pain, diarrhea, vomiting, indigestion, the feeling
of being sick, rashes, itching, hives, and a feeling of weakness.
Consult your doctor if the condition persists for long or worsens.
Uses Of TRIVEDON MR TABLET
- Used to manage ischemic heart disease, angina pectoris, and squeals of infarction
How TRIVEDON MR TABLET Works
TRIVEDON
MR TABLET works by optimizing metabolism of fatty acids and glucose,
thereby allowing more blood flow and oxygen supply to the heart. It also
reduces thickening and scarring of heart tissue. This results in
reducing chest pain due to blood vessel narrowing or blocking.
How to use TRIVEDON MR TABLET
Take
TRIVEDON MR TABLET as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. Your doctor
will decide the correct dose and duration for you depending upon your
age, body weight, and disease condition.
Side Effects Of TRIVEDON MR TABLET
Common
- dizziness
- headache
- abdominal pain
- diarrhoea
- vomiting
- indigestion
- nausea
- rashes, itching, hives
- feeling of weakness
Rare
- fast or irregular heartbeats
Stop taking TRIVEDON MR TABLET and consult your doctor immediately if you experience any of the following:
- signs of low blood pressure such as dizziness, light headiness or fainting, malaise (feeling of being unwell), and fall flushing
- signs
of low platelet count (thrombocytopenia) such as frequent bruising,
superficial bleeding, and prolonged bleeding from wounds - low white blood cell count that increases vulnerability to infections
How To Manage Side Effects
Dizziness Or Drowsiness
TRIVEDON
MR TABLET may cause dizziness, which can be managed by lying down until
the dizziness passes and getting up slowly. Do not bend down suddenly.
Get a lot of rest. Walk slowly and carefully. Take plenty of fluids.
Avoid drinking coffee, alcohol, or smoking. Consult your doctor if the
dizziness persists for long or gets worsened.
Headache
TRIVEDON
MR TABLET may cause headaches, which can be managed by taking lots of
water and resting. Do not skip meals. Do not strain your eyes for long
durations, such as while watching a screen. Avoid drinking alcohol.
Consult your doctor if the headache persists for long or gets worsened.
Indigestion
TRIVEDON
MR TABLET may cause indigestion, which can be managed by reducing tea,
coffee, aerated drinks, or alcohol. Do not eat 3 to 4 hours before going
to bed. Avoid smoking and having spicy or fatty food. Consult your
doctor if the indigestion persists for long or gets worsened.
Warning & Precautions
Pregnancy
Monitoring required
TRIVEDON MR TABLET should not be taken during pregnancy unless clearly necessary. Consult your doctor before taking it.
Breastfeeding
Contraindicated
TRIVEDON MR TABLET is not recommended in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with Caution
Do not drive or operate any machinery if you feel dizzy after taking TRIVEDON MR TABLET.
Alcohol
Consult your doctor
Avoid consumption of alcohol while taking TRIVEDON MR TABLET because it may make you dizzier.
Kidney
Contraindicated
TRIVEDON MR TABLET is not recommended for use if you are having kidney-related problems. Consult your doctor before taking it.
Allergy
Contraindicated
Do
not take TRIVEDON MR TABLET if you are allergic to trimetazidine or any
other ingredient in this medicine. Consult your doctor before taking
it.
Heart Disease
Monitoring required
TRIVEDON
MR TABLET should be used with caution in patients with heart diseases.
This medicine does not manage sudden angina attacks and should not be
used as a management for unstable or heart attacks. Moreover, it may
cause palpitations (irregular heartbeats). Consult your doctor before
taking it.
Use In Pediatrics
Contraindicated
TRIVEDON
MR TABLET is not recommended for use in children and adolescents (below
18 years). Consult your doctor before taking it.
Use In Geriatrics
Use with Caution
TRIVEDON MR TABLET should be used with caution in elderly patients (above 75 years). Consult your doctor before taking it.
Others
TRIVEDON MR TABLET is not recommended for use if you:
- have
Parkinson disease (a brain disorder that affects movement trembling,
rigid posture, slow movements, and a shuffling, unbalanced walk)
Interactions
A. Drug-Drug interactions:
Before
taking TRIVEDON MR TABLET, inform your doctor if you are taking any
other medicines, including medicines obtained without the prescription.
Overdosage:
If
you or anyone else accidentally takes too much of TRIVEDON MR TABLET,
consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | :Â Â | Trimetazidine |
| Pharmacological Category | :Â Â | Anti-anginal drugs |
| Therapeutic Indication | :  | Angina pectoris        |
| Dosage Forms | :Â Â | Tablet, Capsule |
More Information
Storage
- Keep TRIVEDON MR TABLET out of reach of children
- Store at room temperature
FAQs About TRIVEDON MR TABLET
Q: What is the action of TRIVEDON MR TABLET?
A:
TRIVEDON MR TABLET works by optimizing metabolism of fatty acids and
glucose, thereby allowing more blood flow and oxygen supply to the
heart. It also reduces the thickening and scarring of heart tissue. This
results in reducing chest pain due to blood vessel narrowing or
blocking. Consult your doctor before taking it.
Q: Is TRIVEDON MR TABLET good for the heart?
A:
Yes, TRIVEDON MR TABLET is good for the heart in adult patients
suffering from angina pectoris (chest pain caused by a heart disease).
It protects the heart cells from the effects of a reduced oxygen supply
during an episode of angina. Consult your doctor before taking it.
Q: Can TRIVEDON MR TABLET lower blood pressure?
A:
TRIVEDON MR TABLET can cause a fall in blood pressure on standing-up
occasionally, thereby causing dizziness, light headiness or fainting,
malaise (feeling of being unwell), dizziness, and fall flushing. Contact
your doctor or a nearby hospital immediately.
Q: How long should I take TRIVEDON MR TABLET?
A:
Take TRIVEDON MR TABLET as advised by your physician. Your doctor will
decide the correct dose and duration for you depending upon your age,
body weight, and disease condition. Consult your doctor before you stop
taking your medicine.
Q: What are the common side effects of TRIVEDON MR TABLET?
A:
The common side effects associated with TRIVEDON MR TABLET intake are
dizziness, headache, abdominal pain, diarrhea, vomiting, indigestion, a
feeling of being sick, rashes, itching, hives, and a feeling of
weakness. Consult your doctor if the condition persists for long or
worsens.
Q: How do I take TRIVEDON MR TABLET?
A:
Swallow the medicine with a glass of water. Do not crush or chew the
medicine. Your doctor will decide the correct dose and duration for you
depending upon your age, body weight, and disease condition.
Q: What if I forget to take TRIVEDON MR TABLET dose?
A:
If you forget to take one or more TRIVEDON MR TABLET doses, do not take
a double dose to make up for a forgotten dose, as it may lead to
serious consequences. Consult your doctor in such conditions.
Q: When should I stop taking TRIVEDON MR TABLET?
A:
Stop taking TRIVEDON MR TABLET and consult your doctor immediately if
you experience signs of low blood pressure (dizziness, light headiness
or fainting, malaise, dizziness, and fall flushing), low platelet count
(frequent bruising, superficial bleeding, and prolonged bleeding from
wounds), and low white blood cell count that increases vulnerability to
infections.
Q: What is TRIVEDON MR TABLET used for?
A:
TRIVEDON MR TABLET is used in adult patients for the management of
angina pectoris (chest pain caused by a heart disease) along with other
medicines. It protects the heart cells from the effects of a reduced
oxygen supply during an episode of angina.
Q: Can TRIVEDON MR TABLET be used during pregnancy?
A: TRIVEDON MR TABLET should not be taken during pregnancy unless clearly necessary. Consult your doctor before taking it.
Q: What should I avoid while taking TRIVEDON MR TABLET?
A: Avoid consumption of alcohol while taking TRIVEDON MR TABLET because it may make you dizzier.
Q: What precautions must be taken while using TRIVEDON MR TABLET?
A: TRIVEDON MR TABLET should be used with caution in patients with heart diseases.
Q: Who should avoid taking TRIVEDON MR TABLET?
A:
TRIVEDON MR TABLET is not recommended for use if you have Parkinson
disease, kidney-related problems, or are allergic to trimetazidine.
Consult your doctor before taking it.
Q: Is TRIVEDON MR TABLET safe for kids?
A:
TRIVEDON MR TABLET is not recommended for use in children and
adolescents (below 18 years). Consult your doctor before taking it.
References
1. KD. Tripathi. Corticosteroids. Essentials of Medical Pharmacology. Seventh edition. 2013. Page 553-554.
2.
Yuri M. Pozdnyakov. Clinical Acceptability of Trimetazidine Modified
Release 80 mg Once Daily Versus Trimetazidine Modified-Release 35 mg
Twice Daily in Stable Angina Pectoris. National Library of Medicine.
PubMed Central. June 2018. [Assessed on 28th August 2024]Â https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464521
3.
Kirti Gupta, Sneha Pandey, Newly Bagang, Kamalpreet Mehra, and
Gaaminepreet Singh. Trimetazidine, an emerging paradigm in renal
therapeutics: preclinical and clinical insights. National Library of
Medicine. PubMed Central. November 2021. [Assessed on 28th August 2024]Â https://pubmed.ncbi.nlm.nih.gov/34774496/
4.
Agustin Ciapponi, Rudolf Pizarro, and Jeff Harrison. Trimetazidine for
stable angina. National Library of Medicine. PubMed Central. March 2017.
[Assessed on 28th August 2024]Â https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464521/
5.
European Medicine Agency. Assessment Report for
trimetazidine-containing medicinal products. [Revised in September 2012]
[Accessed on 28th August 2024]Â https://www.ema.europa.eu/en/documents/referral/trimetazidine-article-31-referral-assessment-report_en.pdf
6.
Servier (Ireland) Industries Ltd. Health Product Regulatory Authority.
[Revised in February 2021] [Accessed on 28th August 2024]Â http://www.hpra.ie/img/uploaded/swedocuments/fc314b85-1fe6-463e-a6f1-33c49375b2a4.pdf
7. VIANEX S.A. Health Product Regulatory Authority. [Revised in April 2016] [Accessed 2 on 28th August 2024]Â https://www.hpra.ie/img/uploaded/swedocuments/2175323.PPA0465_122_001.7fe02c5a-e650-4c76-9bbe-6ed7fb2b4ef6.000001Vastarel%2020mg%20Tabs%20PIL.160425.pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Serum Electrolytes/ Electrolytes Profile
- Cardiac Risk Profile
- C Reactive Protein (CRP)
- Basic Heart Care
- Advance Heart Care
- Comprehensive Heart Care
- Lipid Profile Test/Cholesterol-Total, Serum
- Cardiac Risk Markers – Advanced
- Cardiac Profile – Advanced
| Weight | 17.5 g |
|---|
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