VEGAZ OD Sachet 2gm
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Introduction About VEGAZ OD SACHET
VEGAZ OD SACHET contains Mesalamine which belongs to the group of medicines called Salicylates. VEGAZ OD SACHET is used to manage mild to moderate attacks of ulcerative colitis, which is a chronic inflammatory bowel disease that affects last part of colon and rectum (back passage) in affected individuals.
VEGAZ OD SACHET is not recommended for use in patients allergic to Mesalamine, salicylates (such as acetylsalisylic acid) and/or sulphasalazine. It is also not recommended for use in patients with bleeding disorders and/or serious kidney/liver disease.
Before taking VEGAZ OD SACHET, inform your doctor if you suffer from an active peptic ulcer (stomach/duodenal ulcer) and/or have lung problems (such as asthma), mild to moderate kidney/liver problems.
VEGAZ OD SACHET should be used with caution in pregnant and breastfeeding women only if it is clearly necessary. It is advised to be used with caution in children and adolescents (aged 6-18 years) and in elderly patients (aged above 65 years) after consulting the doctor.
The most common side effects after taking VEGAZ OD SACHET are abdominal pain, nausea/vomiting, diarrhoea, flatulence, headache and/or rash. Consult your doctor if any of these symptoms worsens.
Uses Of VEGAZ OD SACHET
- Manage mild to moderate attacks of ulcerative colitis in affected individuals
How VEGAZ OD SACHET Works
VEGAZ OD SACHET works by suppressing the production of prostaglandins (chemical messengers responsible for inflammation in the intestines) which results in reduced inflammation and ulceration thus providing relief from ulcerative colitis (and its associated symptoms) in affected individuals.
How to use VEGAZ OD SACHET
Take VEGAZ OD SACHET as advised by your physician. Empty the contents of the sachet onto the tongue and wash the granules down immediately with some water/orange juice or mix the entire content of the sachet with yogurt and immediately intake it without chewing the medicine. Your doctor will decide the exact dose and duration of management for you depending upon your age, body weight and disease condition.
Side Effects Of VEGAZ OD SACHET
Common
- abdominal pain, nausea, vomiting, diarrhoea, flatulence
- headache
- rash
Rare
- signs of inflammation of heart (myocarditis/pericarditis) such as shortness of breath, chest pain, rapid/irregular heart beats
- signs of inflammation of the pancreas such as back/stomach pain
- dizziness
- photosensitivity (increased sensitivity of your skin to sun and ultraviolet light)
Stop taking VEGAZ OD SACHET and consult your doctor immediately in case you experience:
- serious skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis associated with symptoms such as reddish non-elevated, target-like/circular patches on the trunk associated with central blisters, skin peeling, ulcers of eyes, nose, mouth, throat and/or genitals
- signs of severe allergic reaction such as severe skin rashes, difficulty in breathing/swallowing, swelling of the face/neck
- suddenly developed abdominal cramps/pain, fever, severe headache and/or rash
How To Manage Side Effects
Nausea and vomiting:
Take VEGAZ OD SACHET with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.
Diarrhea:
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptom worsens.
Headache:
If VEGAZ OD SACHET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of using VEGAZ OD SACHET. If it lasts more than a week or severe, inform your doctor.
Dizziness:
Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.
Warning & Precautions

Pregnancy
VEGAZ OD SACHET should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. Consult your doctor before taking VEGAZ OD SACHET.

Breastfeeding
VEGAZ OD SACHET should be used with caution in breastfeeding women only if it is clearly necessary since the medicine may cause allergic reactions in new-borns (after breastfeeding). The medicine is advised to be discontinued from use if new-borns develop diarrhoea. Consult your doctor before taking the medicine.

Driving and Using Machines
VEGAZ OD SACHET is unlikely to affect your ability to drive and/or operate machines. Consult your doctor before taking VEGAZ OD SACHET.

Alcohol
Consult and inform your doctor if you are planning to consume alcohol while taking VEGAZ OD SACHET.

Kidney
VEGAZ OD SACHET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients who have/had mild to moderate kidney disease. Consult your doctor before taking VEGAZ OD SACHET.

Liver
VEGAZ OD SACHET is not recommended for use in patients with severe liver problems. It should be used with caution in patients who have/had mild to moderate liver disease. Consult your doctor before taking VEGAZ OD SACHET.

Allergy
Do not take VEGAZ OD SACHET if you are allergic to Mesalamine, salicylates, sulfasalazine and/or any other ingredients of this medicine.

Lungs
VEGAZ OD SACHET should be used with caution in patients with lung problems such as bronchial asthma. Consult your doctor before taking VEGAZ OD SACHET.
Others
VEGAZ OD SACHET is not recommended for use if you:
- suffer from bleeding disorders
Before taking VEGAZ OD SACHET inform your doctor if you:
- have an active peptic ulcer (stomach/duodenal ulcer)
Use in Paediatrics:
VEGAZ OD SACHET is advised to be used with caution in children and adolescents (aged 6-18 years). Consult your doctor before administering the medicine to the child.
Use in Geriatrics:
VEGAZ OD SACHET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking VEGAZ OD SACHET.
Interactions
A. Drug-Drug interactions:
Before taking VEGAZ OD SACHET, inform your doctor if you are taking any of the following medicine:
- antacids (medicines used to relieve indigestion and heartburn) Ex. aluminum hydroxide, magnesium carbonate
- azathioprine (used after transplantations or to manage autoimmune diseases)
- mercaptopurine, thioguanine (medicines used to manage leukaemia)
- medicines used to manage blood clotting (Ex. warfarin)
- non- steroidal anti-inflammatory drugs (medicines used to reduce fever and provide relief from pain) Ex. ibuprofen, diclofenac, ketorolac
Overdosage:
If you or anyone else accidentally takes too much of VEGAZ OD SACHET, consult your doctor immediately or visit the nearby hospital to manage the overdose symptoms.
Synopsis
Drug | :Â Â | Mesalamine |
Pharmacological Category | :Â Â | Salicylates |
Therapeutic Indication | :Â Â | Ulcerative colitis |
Dosage Forms | :  | Tablets, Suppositories, Sachet, Granules, Powder, Pellet, Enema |
More Information
- Keep VEGAZ OD SACHET out of reach of children
- Store VEGAZ OD SACHET at room temperature
FAQs About VEGAZ OD SACHET
What is VEGAZ OD SACHET used for?
VEGAZ OD SACHET is used to manage mild to moderate attacks of ulcerative colitis, which is a chronic inflammatory bowel disease that affects last part of colon and rectum (back passage) in affected individuals.
How to take VEGAZ OD SACHET?
Take VEGAZ OD SACHET as advised by your physician. Empty the contents of the sachet onto the tongue and wash the granules down immediately with some water/orange juice or mix the entire content of the sachet with yogurt and immediately intake it without chewing the medicine. Your doctor will decide the exact dose and duration of management for you depending upon your age, body weight and disease condition.
What are the side effects of VEGAZ OD SACHET?
The most common side effects after taking VEGAZ OD SACHET are abdominal pain, nausea/vomiting, diarrhoea, flatulence, headache and/or rash. Consult your doctor if any of these symptoms worsens.
How VEGAZ OD SACHET works?
VEGAZ OD SACHET works by suppressing the production of prostaglandins (chemical messengers responsible for inflammation in the intestines) which results in reduced inflammation and ulceration thus providing relief from ulcerative colitis (and its associated symptoms) in affected individuals.
Can VEGAZ OD SACHET be used in pregnant and breastfeeding women?
Yes, VEGAZ OD SACHET can be used but with caution in pregnant and breastfeeding women only if it is clearly necessary. Consult your doctor before taking VEGAZ OD SACHET.
References
1. KD. Tripathi. Drugs for Constipation and Diarrhoea. Essentials of medical pharmacology. Seventh edition. 2013. Page – 684.
2. Marietta Iacucci, Shanika de Silva, Subrata Ghosh. Â Mesalazine in inflammatory bowel disease: A trendy topic once again? NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in February 2010] [Accessed on 18th October 2022]Â https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852235/
3. Ashwin N. Ananthakrishnan, Tamara Donaldson, Karen Lasch, Vijay Yajnik. Management of Inflammatory Bowel Disease in the Elderly Patient: Challenges and Opportunities. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in June 2018] [Accessed on 18th October 2022]Â https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687915/
4. Ferring GmbH. Health Products Regulatory Authority (HPRA). [Revised in February 2022] [Accessed on 18th October 2022]Â https://www.hpra.ie/img/uploaded/swedocuments/9945a6a2-aeec-49e9-80b5-90d028e5154b.pdf
5. Taj Pharma India. Meslataj 0.5gm/1gm/2gm. [Accessed on 18th October 2022] https://tajpharma.in/portfolio-item/mesalazine-sachet-1gm-prolonged-release-granules-meslataj-taj-pharma/
Weight | 2 g |
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