How VOAGE MS 1000 TABLET Works
VOAGE MS 1000 TABLET is a combination of dapagliflozin, metformin, and sitagliptin. Dapagliflozin works by inhibiting the reabsorption of glucose in the kidneys, increasing urinary glucose excretion, and reducing blood glucose levels. Metformin decreases the amount of glucose you absorb from your food and the amount of glucose made by the liver. It also increases the body’s response to insulin, a natural substance that controls the amount of glucose in the blood. Sitagliptin helps control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.
How to use VOAGE MS 1000 TABLET
- Take VOAGE MS 1000 TABLET as advised by your physician.
- It can be taken with or without meals. However, taking this medicine with meals help reduce gastrointestinal discomfort
- Swallow this medicine whole with a glass of water, and do not crush or chew the medicine.
- Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
- Do not stop taking this medicine without consulting your doctor. Otherwise, your blood sugar will rise again.
Side Effects Of VOAGE MS 1000 TABLET
Common Side Effects of VOAGE MS 1000 TABLET:
- Hypoglycemia (low blood glucose level)
- Nausea, vomiting
- Headache
- Flatulence
- Genital infections
- Increased or more frequent urination
- Drowsiness, dizziness
- Diarrhea, constipation
- Stomach pain
- Itching
- Dry mouth
- Decreased weight
- Thirst
Stop taking VOAGE MS 1000 TABLET and consult your doctor immediately if you experience any of the following side effects:
- Symptoms of acute pancreatitis, such as severe and persistent abdominal pain that might reach through your back with or without nausea and vomiting
- Symptoms of allergic reactions such as rash, hives, blisters on the skin or peeling skin, and swelling of the face, lips, tongue, and throat that may cause difficulty breathing or swallowing
- Signs of bullous pemphigoid, such as blistering of the skin
- Symptoms of lactic acidosis include vomiting, abdominal pain, muscle cramps, a general feeling of not being well, severe tiredness, difficulty breathing, reduced body temperature, and a slow heartbeat
- The symptoms of diabetic ketoacidosis are nausea, vomiting, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to your breath, a sweet or metallic taste in your mouth, or a different odour to your urine or sweat, or rapid weight loss
- Signs of severe infections of the urinary tract include fever, chills, a burning sensation during urination, pain in your back or side, and blood in your urine
How To Manage Side Effects
Constipation
Include fiber-rich foods in your diet, such as fresh fruits, vegetables, and whole-grain cereals, and drink plenty of fluids. Exercise more regularly and stay active. Contact your doctor if constipation persists.
Diarrhea
Drink lots of fluids, such as water or fruit juices, to keep yourself hydrated. Do not take any medicine on your own to manage diarrhea. Contact your doctor if your diarrhea does not improve.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive amounts of alcohol. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids, such as water or electrolytes. Applying a pain-relieving balm to your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Warning & Precautions
Pregnancy
Consult your doctor
There are no well controlled human studies regarding the use of Dapagliflozin + Sitagliptin + Metformin in pregnant women. Animal studies have indicated few harmful side effects in their progeny. Therefore, VOAGE MS 1000 TABLET should be taken by pregnant women only if your doctor considers it as clearly necessary.
Breastfeeding
Consult your doctor
It is not known whether the medicines, Dapagliflozin + Sitagliptin + Metformin gets excreted in breast milk. Animal studies have reported the excretion of medicine in milk as well as pharmacologically mediated effects in nursing offspring. A risk to the infant cannot be excluded. Therefore, breastfeeding women should not take VOAGE MS 1000 TABLET unless considered necessary by the physician.
Driving and Using Machines
Use with Caution
Do not drive or operate any machines if you have dizziness and drowsiness after taking VOAGE MS 1000 TABLET.
Alcohol
Consult your doctor
Avoid consumption of alcohol while taking VOAGE MS 1000 TABLET, as it may increase the risk of lactic acidosis.
Kidney
Consult your doctor
VOAGE MS 1000 TABLET is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with mild to moderate kidney disease. Consult your doctor before taking it.
Liver
Contraindicated
VOAGE MS 1000 TABLET is not recommended for use if you have liver disease. Consult your doctor before taking it.
Allergy
Contraindicated
VOAGE MS 1000 TABLET is not recommended for use if you are allergic to dapagliflozin, metformin, sitagliptin, or any of the other ingredients of this medicine.
Lungs
Contraindicated
VOAGE MS 1000 TABLET is not recommended for use if you have respiratory failure. Consult your doctor before taking it.
Heart Disease
Contraindicated
VOAGE MS 1000 TABLET is not recommended for use if you have heart failure or a recent myocardial infarction. Consult your doctor before taking it.
Use In Pediatrics
Contraindicated
VOAGE MS 1000 TABLET is not recommended for use in children and adolescents below 18 years of age as safety and efficacy are not clinically established. Contact your doctor before taking.
Use In Geriatrics
Use with Caution
VOAGE MS 1000 TABLET should be used with caution in elderly patients (aged 65 years or older). Contact your doctor before taking.
Others
VOAGE MS 1000 TABLET is not recommended for use if you:
- Have Type 1 diabetes mellitus
- Have acute metabolic acidosis (such as lactic acidosis or diabetic ketoacidosis)
- Have diabetic pre-coma
- Have dehydration
- Have a severe infection
- Have shock
- Are scheduled for a lab test
- Are planned for surgery
Before taking VOAGE MS 1000 TABLET, inform your doctor if you:
- Have a history of pancreatitis
- Have or have had gallstones
- Have very high levels of triglycerides (a form of fat) in your blood
| Weight | 30 g |
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