- 6%
Xone 500mg Injection 1’s
Original price was: ₹51.00.₹48.00Current price is: ₹48.00.
* Mkt: Alkem Laboratories Ltd
* Country of Origin: India
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INTRODUCTION ABOUT XONE 500MG INJECTION
XONE
500MG INJECTION contains Ceftriaxone, which belongs to the group of
medicines called Antibiotics. It is used to manage bacterial infections
such as urinary tract infections, lower respiratory tract infections,
bacteraemia, septicaemia, meningitis, abdominal infections, and
infections caused by pseudomonas species. XONE 500MG INJECTION is also
used to manage infections, before and after surgery.
Tell your
doctor before receiving XONE 500MG INJECTION if you have or had a
history of kidney or liver diseases, fungal diseases, gastrointestinal
disease, or diarrhea. If you are pregnant or breastfeeding, inform your
doctor before receiving XONE 500MG INJECTION.
Inform your doctor
if you are allergic (hypersensitive) to cephalosporins, penicillin, or
any antibiotics before receiving the medicine.
Your doctor will
administer the right dose depending on your child’s age, body weight,
and disease condition. XONE 500MG INJECTION should be used with caution
in elderly patients; consult your doctor before receiving the medicine.
The
most common side effects of receiving this medicine are pain,
tenderness, hardness, or at the injection site and diarrhea. Consult
your doctor immediately if any of the above symptoms worsen.
USES OF XONE 500MG INJECTION
Used to manage:
- Urinary tract infections
- Lower respiratory tract infections
- Bacteraemia
- Septicaemia
- Meningitis
- Abdominal infections and
- Infections caused by pseudomonas species
HOW XONE 500MG INJECTION WORKS
XONE
500MG INJECTION contains ceftriaxone, which is a second-generation
cephalosporin that interferes with the synthesis of the bacterial cell
wall by binding to specific binding proteins located inside the
bacterial cell wall. This leads to breaking down the cell wall of the
bacteria and reducing its stability, thus causing cell damage and
eventually causing bacterial elimination.
DIRECTIONS FOR USE
XONE
500MG INJECTION will be given to you intravenously or intramuscularly
only by a doctor or nurse. Your doctor will administer the right dose
depending on your age, body weight, and severity of the infection.
SIDE EFFECTS OF XONE 500MG INJECTION
COMMON
- Abnormalities with white blood cells (such as a decrease of leucocytes and an increase of eosinophils) and platelets
- Diarrhea
- Thrombocytosis
- Leukopenia
- Headache
- Dizziness
- Changes in liver function
UNCOMMON
- Anaemia
- Nausea and vomiting
- Pruritis (itching sensation)
- Increased blood creatinine levels
- Fungal infections
- Decrease in white blood cells (granulocytopenia)
- Blood clots (pain and swelling of your joints)
- Pain or a burning feeling along the vein
- Fever
RARE
- Bronchospasm (breathing difficulty)
- Haematuria (blood in urine)
- Glycosuria (glucose in urine)
- Chills
- Inflammation of the colon. Signs include diarrhea, usually with blood and mucus
- Lumpy rash (hives), feeling itchy and swelling
- Oedema (fluid buildup)
Contact your doctor if you experience any of the following side effects:
- Sudden swelling of the face, throat, lips, or mouth. This can make it difficult to breathe or swallow
- Severe rash that develops quickly, with blisters or peeling of the skin and possibly blisters in the mouth
- Widespread rash, high body temperature, liver enzyme
- Elevations, blood abnormalities (eosinophilia)
- Enlarged lymph nodes and other body organ involvement
- Jarisch-Herxheimer reaction, which causes fever, chills, headache, muscle pain, and skin rash
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink
lots of fluids, such as water or fresh juice, to keep yourself
hydrated. Do not take any medicine on your own for managing diarrhea.
Consult your doctor if the symptom does not improve.
Headache
Apply a pain-relieving balm on their head if required. Consult your doctor if the symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
Monitoring required
XONE 500MG INJECTION should be used during pregnancy only if clearly needed. Consult your doctor before receiving this medicine.
BREASTFEEDING
Use with Caution
XONE
500MG INJECTION should be used with caution during breastfeeding as it
may pass into the breast milk. Consult your doctor before receiving this
medicine.
DRIVING AND USING MACHINES
Contraindicated
Do not drive or handle any heavy machines if you experience dizziness or lightheadedness while receiving XONE 500MG INJECTION.
KIDNEY
Use with Caution
XONE
500MG INJECTION should be used with caution in patients with kidney
disease. Consult your doctor before receiving this medicine.
LIVER
Use with Caution
XONE
500MG INJECTION should be used with caution in patients with liver
diseases. Consult your doctor before receiving this medicine.
ALLERGY
Contraindicated
Do
not receive XONE 500MG INJECTION if you are allergic (hypersensitive)
to ceftriaxone or to any other ingredients of this medicine.
USE IN PEDIATRICS
Consult your doctor
Your
doctor will administer the right dose depending on your child’s age,
body weight, and severity of the infection. Consult your doctor before
receiving XONE 500MG INJECTION.
USE IN GERIATRICS
Use with Caution
XONE 500MG INJECTION should be used with caution in elderly patients. Consult your doctor before receiving this medicine.
OTHERS
XONE 500MG INJECTION is not recommended for use if you have:
- Gastrointestinal disease (colitis)
Before receiving XONE 500MG INJECTION, inform your doctor if you:
- Have
hemolytic anemia (a reduction in your red blood cells that may make
your skin pale yellow and cause weakness or breathlessness) - Are on a low-sodium diet
INTERACTIONS
A. Drug-Drug interactions:
Before receiving XONE 500MG INJECTION, inform your doctor if you are receiving any of the following medicine:
- Aminoglycoside (manages infections)
- Chloramphenicol (used to manage infections, particularly of the eyes)
Overdosage:
It
is unlikely to receive an overdose since it will be administered by the
doctor or nurse. If you experience any unusual side effects, consult
your doctor immediately.
SYNOPSIS
| Drug | :Â Â | Ceftriaxone |
| Pharmacological Category | :Â Â | Cephalosporin Antibiotics |
| Therapeutic Indication | :Â Â | Manages Bacterial infections |
| Dosage Forms | :Â Â | Injection |
MORE INFORMATION
STORAGE
- Keep out of reach of children
- Store at room temperature
FAQs ABOUT XONE 500MG INJECTION
Q: What is XONE 500MG INJECTION used for?
A:
XONE 500MG INJECTION is used to manage bacterial infections such as
urinary tract infections, lower respiratory tract infections,
bacteraemia, septicaemia, meningitis, abdominal infections, and
infections caused by pseudomonas species. XONE 500MG INJECTION is also
used to manage infections before and after surgery.
Q: Can XONE 500MG INJECTION be given to breastfeeding mothers?
A:
XONE 500MG INJECTION should be used with caution as it may pass into
the breast milk. Consult your doctor before receiving. It should only be
given if the expected benefits outweigh any potential risk to the baby.
Q: Can XONE 500MG INJECTION cause diarrhea?
A:
Yes, XONE 500MG INJECTION may cause diarrhea during or after use.
Usually, discontinuation of medicine can subside diarrhea. However, if
diarrhea persists or if there is blood in the stool, then immediately
consult your doctor.
Q: Is XONE 500MG INJECTION safe during pregnancy?
A:
XONE 500MG INJECTION should be used during pregnancy only if clearly
needed. Consult your doctor before receiving this medicine.
Q: What precautions must be followed while using XONE 500MG INJECTION?
A:
XONE 500MG INJECTION should be used with caution in patients with
kidney disease, liver diseases, hemolytic anemia (a reduction in your
red blood cells that may make your skin pale yellow and cause weakness
or breathlessness) or are on a low sodium diet. Consult your doctor
before receiving this medicine.
Q: Who should not use XONE 500MG INJECTION?
A:
XONE 500MG INJECTION is not recommended for use if you have
gastrointestinal disease (colitis) or if you are allergic to Ceftriaxone
or to any other ingredients of this medicine.
Q: Can XONE 500MG INJECTION be used in children?
A:
Your doctor will administer the right dose depending on your child’s
age, body weight, and severity of the infection. Consult your doctor
before receiving XONE 500MG INJECTION.
Q: How XONE 500MG INJECTION is given?
A:
XONE 500MG INJECTION will be given to you intravenously or
intramuscularly only by a doctor or a nurse. Your doctor will administer
the right dose depending on your age, body weight, and severity of the
infection.
Q: How does XONE 500MG INJECTION work?
A:
XONE 500MG INJECTION contains ceftriaxone, which is a second-generation
cephalosporin that interferes with the synthesis of the bacterial cell
wall by binding to specific binding proteins located inside the
bacterial cell wall. This leads to breaking down the cell wall of the
bacteria and reducing its stability, thus causing cell damage and
eventually causing bacterial elimination.
Q: Can I use other medicines along with XONE 500MG INJECTION?
A:
Before receiving XONE 500MG INJECTION, inform your doctor if you are
receiving prescription, non-prescription, or herbal medicines.
REFERENCES
1. KD. Tripathi. Nonsteroidal Antimicrobials. Essentials of medical pharmacology. Seventh edition. 2013. Page – 728.
2.
D M Richards, R C Heel, R N Brogden, T M Speight, and G S Avery.
Ceftriaxone. A review of its antibacterial activity, pharmacological
properties, and therapeutic use. NIH: National Library of Medicine,
National Center of Biotechnology Information Pubmed.gov. Jun 1984.
[Accessed on 25th July 2024] https://pubmed.ncbi.nlm.nih.gov/6329638
3. ACS DOBFAR S.p.A. Electronic Medicines Compendium (EMC) [Revised in August 2021] [Accessed on 25th July 2024]Â https://www.medicines.org.uk/emc/files/pil.1362.pdf
4. Hospira, Inc [Revised in Oct 2017] [Accessed on 25th July 2024]Â https://labeling.pfizer.com/ShowLabeling.aspx?id=4387#section-15
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count (CBC)/ Hemogram
- Kidney Function Test (KFT)
- Peripheral Smear Examination By Pathologist
- Serum Electrolytes/ Electrolytes Profile
- Culture & Sensitivity, Blood
- Healthy Midlife Checkup
- Urine Routine & Microscopy
- Women Health Checkup – Essential
- Full Body Checkup – Gold
| Weight | 20 g |
|---|
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