Name: Clomipure 50mg Capsule 5'S
SKU: bi/med/158
Availability: InStock

INTRODUCTION ABOUT CLOMIPURE 50MG CAPSULE

CLOMIPURE
50MG CAPSULE is a combination of Clomiphene Citrate and Melatonin,
which belong to the groups of medicines called Ovarian stimulants and
Nutraceutical products, respectively. It is used in the management of
female infertility, which means not being able to get pregnant after at
least one year of trying (or 6 months if the woman is over age 35) or a
woman who keeps having miscarriages. It can result from age, physical
problems, hormone problems and lifestyle or environmental factors and
present as abnormal periods, heavy menstrual bleeding or lighter than
usual, irregular periods, the number of days in between each period
varying each month, painful periods or periods that suddenly stop.

Before
starting CLOMIPURE 50MG CAPSULE, your doctor should check for any other
causes of fertility problems. CLOMIPURE 50MG CAPSULE is not recommended
for use in patients with liver disease, unusual menstrual bleeding
where the cause is not known, hormone-dependent cancers or ovarian
cysts. Before taking CLOMIPURE 50MG CAPSULE, inform your doctor if you
have early menopause or stopped having periods because you are
underweight, have uterine fibroids, polycystic ovaries or swollen
ovaries, hypertriglyceridemia, epilepsy, autoimmune disease, diabetes or
smoking habit.

CLOMIPURE 50MG CAPSULE is generally not
recommended for use in pregnant women, breastfeeding women, children,
adolescents (below 18 years of age) and post-menopausal women. The
common side effects of CLOMIPURE 50MG CAPSULE are flushing, pelvic
discomfort or abdominal distention or bloating, nausea and vomiting,
painful breasts and headaches. If any of these become worse, contact
your doctor.

USES OF CLOMIPURE 50MG CAPSULE

Used to manage female infertility

HOW CLOMIPURE 50MG CAPSULE WORKS

CLOMIPURE
50MG CAPSULE is a combination of Clomiphene citrate that selectively
binds to estrogen hormone receptors in the brain, ovary, endometrium and
cervix to increase the secretion of the luteinizing hormone as well as a
follicle-stimulating hormone for the release of a mature egg from
ovaries and Melatonin improves egg quality by reducing the damage, which
in turn leads to higher fertilization rate. This collective action is
useful in managing female infertility.

DIRECTIONS FOR USE

Take
CLOMIPURE 50MG CAPSULE as advised by your physician. Swallow the
medicine with a glass of water. Do not crush or chew the medicine. The
correct dose and duration for you will be decided by your doctor,
depending on your age, body weight and disease condition.

SIDE EFFECTS OF CLOMIPURE 50MG CAPSULE

COMMON

Vasomotor flushes
Pelvic discomfort or abdominal distention/bloating
Nausea
Vomiting
Discomfort and pain in the breast
Headache
Drowsiness

UNCOMMON

Blurred vision
Cloudy lenses in the eye
Increased pain with periods, heavy periods or bleeding between periods
Irritability, nervousness, restlessness, abnormal dreams and anxiety
Dizziness
Increased blood pressure
Stomach pain with indigestion, ulcers in mouth, dry mouth
Itching, rash, dry skin
Passing glucose, excess protein in the urine
Increase in weight

RARE

Constipation
Depression
Tiredness
Hair loss/dry hair
Increased urinary frequency or volume
Difficulty in falling asleep
Vaginal dryness
Head spinning sensation
Increased fat molecules (triglycerides) in the blood
Altered mood, aggression, increased sex drive
Restless legs syndrome
Pins and needles sensation
Watery eyes
Excessive saliva and bad breath
Nail disorder
Joint pain and muscle spasms
Thirst
Abnormal levels of electrolytes in the blood

Stop taking CLOMIPURE 50MG CAPSULE and contact your doctor immediately if you experience any of the following side effects:

Signs
of an allergic reaction (skin rash, itching, difficulty breathing,
shortness of breath, swelling of your face, lips, throat or tongue, cold
clammy skin, palpitations, dizziness, weakness or fainting)
Signs
of stroke (numbness, weakness or paralysis on one side of your body,
slurred speech, sudden blurred vision, confusion or unsteadiness)
Over-stimulation
of the ovary (pain in the pelvis, stomach or calves, swelling or
feeling bloated, passing less urine, difficulty in breathing or an
increase in weight)
Blurring of vision or spots or flashes in front of the eyes.
Signs of a liver problem (yellowing of eyes or skin)
Sudden and severe headaches
Psychosis
Chest pain and feeling your heartbeat (‘pounding chest’)
Reduced number of white blood cells and platelets, which increases the risk of bleeding or bruising
Blood (red blood cells) in the urine

HOW TO MANAGE SIDE EFFECTS

Bloating

Eat
smaller and more frequent meals, drink a lot of water and go for small
walks after each meal. In the event of no improvement, consult your
doctor.

Headache

Try
to relax and rest yourself. Apply pain balm to the head to ease the
pain. Sip on some hot water or ginger tea. In case of no improvement,
contact your doctor for advice.

Nausea And Vomiting

Take
this medicine with meals or just after meals. Stick to simple meals and
avoid eating oil-rich or spicy foods. In case of no improvement,
consult your doctor.

Stomach Pain

Take
a break for relaxation. Eat and drink slowly or try to have smaller and
more frequent meals. Keep a heating pad on your stomach. In the event
of no improvement, consult your doctor.

WARNING & PRECAUTIONS

PREGNANCY

Contraindicated

CLOMIPURE
50MG CAPSULE is not recommended for use in pregnant women or in women
who think they may be pregnant. You should take a pregnancy test before
taking the medicine. Consult your doctor for advice.

BREASTFEEDING

Contraindicated

CLOMIPURE
50MG CAPSULE is not recommended for breastfeeding women as it is
excreted in human milk and poses a risk to the sucking child. Therefore,
consult your doctor for advice.

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate any machines if you feel drowsy or blurred vision after taking CLOMIPURE 50MG CAPSULE.

ALCOHOL

Consult your doctor

Avoid
consuming alcohol while taking CLOMIPURE 50MG CAPSULE as it can impair
sleep and concentration and potentially worsen side effects such as
headache and tiredness.

KIDNEY

Use with Caution

CLOMIPURE 50MG CAPSULE should be used cautiously in patients having impaired kidney function. Consult your doctor for advice.

LIVER

Contraindicated

CLOMIPURE 50MG CAPSULE is not recommended for use in patients having or ever had liver disease. Consult your doctor for advice.

ALLERGY

Contraindicated

Do not take CLOMIPURE 50MG CAPSULE if you are allergic to Clomiphene citrate or Melatonin.

USE IN PEDIATRICS

Contraindicated

CLOMIPURE
50MG CAPSULE is generally not recommended for use in children and
adolescents (under 18 years of age). Consult your doctor for advice.

USE IN GERIATRICS

Contraindicated

CLOMIPURE 50MG CAPSULE is not recommended for use in women who have already gone through menopause (post-menopausal).

OTHERS

CLOMIPURE 50MG CAPSULE is not recommended for use if you:

Have unusual menstrual bleeding due to an unknown cause
Have hormones-dependent cancer
Have an ovarian cyst

Before taking CLOMIPURE 50MG CAPSULE, inform your doctor if you:

Have early menopause or have been told you are infertile
Are periods stopped because of under-weight
Have uterine fibroids
Have polycystic ovaries or swollen ovaries
Have hypertriglyceridemia or a family history of hypertriglyceridemia
Have epilepsy
Have an autoimmune disease
Have diabetes or impaired glucose tolerance
Have a smoking habit

INTERACTIONS

A. Drug-Drug interactions:

Before taking CLOMIPURE 50MG CAPSULE, inform your doctor if you are taking any of the following medicine:

Fluvoxamine (used in depression and obsessive-compulsive disorder management)
Psoralens (used in managing skin disorders)
Cimetidine (used for managing stomach ulcers)
Estrogens (used to manage pregnancy or hormone replacement preparations)
Ciprofloxacin, enoxacin, gemifloxacin (used in the management of bacterial infections)
Rifampicin (used to manage tuberculosis)
Carbamazepine (used in the management of epilepsy)
Medicines used to induce sleep (Ex. midazolam, temazepam, zaleplon, zolpidem, zopiclone)
Warfarin (used to manage blood clotting)

Weight	17.5 g

General Inquiries

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INTRODUCTION ABOUT CLOMIPURE 50MG CAPSULE

USES OF CLOMIPURE 50MG CAPSULE

HOW CLOMIPURE 50MG CAPSULE WORKS

DIRECTIONS FOR USE