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DIZERAL AZ Tablet 10’s
Original price was: ₹68.00.₹65.00Current price is: ₹65.00.
*10 Tablet(s) in a Strip
* Mkt: Unimarck Healthcare Ltd
* Country of Origin: India
* Delivery charges if applicable will be applied at checkout
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INTRODUCTION ABOUT DIZERAL AZ TABLET
DIZERAL
AZ TABLET is a combination of Alprazolam and Propranolol which belongs
to the group of medicines called Anxiolytics and Antihypertensive agents
respectively. It is used to manage anxiety and panic attacks. It can
also be used to reduce elevated heart rate and blood pressure associated
with anxiety. It is also capable of reducing tremor (shakiness),
restlessness and migraine headache among the affected patients.
Before
taking DIZERAL AZ TABLET inform your doctor if you have any problems in
your heart, liver or kidneys. You must also inform your doctor if you
have diabetes, muscle weakness, depression with suicidal thoughts, any
mental illnesses, history of alcoholism or drug abuse or thyroid
problems as a precaution. Avoid consumption of alcohol while taking this
medicine as it may make you feel more dizzy or drowsy.
Do not
take DIZERAL AZ TABLET without consulting your doctor if you are
pregnant or breastfeeding. The most common side effects of taking this
medicine are depression, headache, dizziness, drowsiness, forgetfulness,
constipation, dry mouth, decreased sex drive, problems in erection,
blurred vision, cold hands and feet, slow heartbeat and problems in
sleeping. Consult your doctor if any of these side effects trouble you.
You
must also inform your doctor immediately if you experience suicidal
thoughts or any other unusual changes in behaviour (such as agitation,
restlessness, aggressiveness, irritability, violence or anger).
USES OF DIZERAL AZ TABLET
- Reduces anxiety and restlessness
- Manage panic attacks, tremors (shakiness) and migraine headache
- Reduces chest pain and high blood pressure caused due to anxiety
HOW DIZERAL AZ TABLET WORKS
DIZERAL
AZ TABLET contains two medicines namely alprazolam and propranolol.
Alprazolam is a hypnotic medicine. It suppresses the abnormal electrical
activity within the brain and induces sleep.
Propranolol is a
beta-blocker. It reduces the heart rate and force of contraction of the
heart which, therefore reduces abnormal heart signs (such as racing
heartbeat, nervousness and high blood pressure) associated with anxiety.
It
can also relax the blood vessels supplying the heart and the brain
which therefore reduces elevated blood pressure, chest pain and
migraine.
It also stops the transfer of abnormal nerve signals between the brain and the muscles which helps in reducing tremors.
DIRECTIONS FOR USE
Take
DIZERAL AZ TABLET as directed by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine.
Your
doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and health condition. Do not take
this medicine for more than 4 weeks without consulting your doctor.
SIDE EFFECTS OF DIZERAL AZ TABLET
COMMON
- depression
- headache, dizziness
- drowsiness or sleepiness
- jerky movements or unsteadiness
- forgetfulness
- slurred speech, nervousness
- constipation, dry mouth, loss of appetite
- tiredness, irritability, confusion, disorientation, loss of alertness
- sexual problems, increased or decreased sex drive
- problems in erection
- feeling sluggish
- shakiness or trembling
- double or blurred vision
- nausea
- change in body weight
- fingers and toes may become cold
- slow heartbeat
- signs of Raynaud’s syndrome (numbness and spasm in the fingers followed by warmth and pain)
- sleep disturbances, nightmares
UNCOMMON
- diarrhea
- abnormally excited
- hallucinations
- urge to urinate
- menstrual cramps (pain in thighs and lower back)
- muscle spasms or weakness
RARE
- dizziness while standing up
- hair loss
- tingling or pricking sensation of body parts
- vision disturbances and dry eyes
Stop taking DIZERAL AZ TABLET and contact your doctor immediately if you experience any of the following side effects such as:
- signs
of allergic reactions (such as skin rash, swelling of the face, lips,
mouth or throat which can lead to difficulty in breathing or swallowing) - slow heart rate and low blood pressure causing dizziness, light-headedness, fainting or blurred vision
- changes
in behavior (such as feeling agitated, restless, aggressive, irritable,
violent or angry, false beliefs, nightmares and hallucinations or other
inappropriate behavior) - memory loss (amnesia)
- yellowing of the skin and the whites of the eye (jaundice)
HOW TO MANAGE SIDE EFFECTS
Constipation
Eat
plenty of fiber rich foods such as fresh fruits, vegetables and
cereals. Drink plenty of fluids. Exercise more regularly. Consult your
doctor if this side effect bothers you.
Dizziness Or Drowsiness
Try
to rest and relax. Get enough sleep. Avoid driving or operating any
tools or machines completely while you are feeling dizzy. Do not consume
excessive alcohol, as it could aggravate your dizziness. Consult your
doctor if your dizziness worsens.
Headache
Rest
and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead
can be beneficial. Do not consume excessive alcohol, as it could
aggravate your headache. Consult your doctor if your headache worsens.
Insomnia
Try
to have a regular bedtime schedule. Avoid having naps during the
daytime. Limit caffeine intake and reduce watching TV before bedtime. If
the symptom does not improve, consult your doctor.
Nausea And Vomiting
Take
DIZERAL AZ TABLET with or just after a meal or a snack. Stick to simple
meals. Avoid eating rich or spicy food. Consult your doctor if your
nausea worsens.
WARNING & PRECAUTIONS
PREGNANCY
Contraindicated
DIZERAL
AZ TABLET is generally not recommended for use in pregnant women unless
considered necessary by the physician, as it may harm the growing baby.
Therefore, inform your doctor before taking DIZERAL AZ TABLET if you
are pregnant, think you might be pregnant or planning to have a baby.
BREASTFEEDING
Contraindicated
DIZERAL
AZ TABLET may excrete in breast milk. Therefore, it is not recommended
for use in breastfeeding women. However, consult your doctor for advice
before taking it.
DRIVING AND USING MACHINES
Use with Caution
Do not drive or handle any heavy tools or machines if you experience dizziness or drowsiness after taking DIZERAL AZ TABLET.
ALCOHOL
Consult your doctor
Avoid consumption of alcohol while taking DIZERAL AZ TABLET as it might make you feel dizzier and drowsier.
KIDNEY
Use with Caution
DIZERAL AZ TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
LIVER
Consult your doctor
DIZERAL
AZ TABLET is not recommended for use in patients with severe liver
problems. It should be used with caution in patients with other mild
liver problems. Therefore, consult your doctor before taking it.
ALLERGY
Contraindicated
Do
not take DIZERAL AZ TABLET if you are allergic to propranolol,
alprazolam or to any other sedative or hypnotic medicines (such as
midazolam, nitrazepam, clonazepam).
LUNGS
Contraindicated
DIZERAL
AZ TABLET is not recommended for use in patients suffering from asthma,
chronic bronchitis, emphysema, COPD or bronchospasm. Therefore, consult
your doctor before taking it.
HEART DISEASE
Consult your doctor
DIZERAL
AZ TABLET is not recommended for use in patients with sinus bradycardia
(slow heart beat due to problems in SA nodes), heart block, severe
hypotension (low blood pressure), congestive heart failure or heart
defects. It should be used with caution in patients with a previous
history of heart failure or other heart problems. Therefore, consult
your doctor before taking it.
OTHERS
DIZERAL AZ TABLET is not recommended for use if you:
- have cardiogenic shock (heart cannot pump blood suddenly)
- have hypertensive emergency crisis (abnormal increase in blood pressure which is severe)
- have an increased acidity of the blood (metabolic acidosis)
- are on a strict fasting diet
- suffer from other forms of angina (Prinzmetal’s angina)
- suffer from myasthenia gravis (severe muscle weakness)
- have sleep apnea (breathing stops and starts during sleep)
Before taking DIZERAL AZ TABLET, inform your doctor if you:
- have diabetes
- suffer from unstable angina (chest pain that occurs in the absence of any stressful activity)
- are going for glaucoma screening test
- are planning for any major surgery
- have other types of arrhythmias (such as Wolf-Parkinson-White Syndrome)
- have any bleeding problems
- have stroke or any circulatory problems
- have swollen ankles
- have previously experienced depression with thoughts of committing suicide
- have any mental illnesses that required hospitalization
- have a previous experience of drug abuse or alcoholism
- have used any hypnotic medicine earlier
Use in Pediatrics:
DIZERAL
AZ TABLET is not recommended for use in children and adolescents (aged
below 18 years) due to lack of safety data. Therefore, consult your
doctor before taking it.
Use in Geriatrics:
DIZERAL
AZ TABLET should be used with caution in elderly patients (aged above
65 years). Therefore, consult your doctor before taking it.
INTERACTIONS
A. Drug – Drug interactions:
Before taking DIZERAL AZ TABLET, inform your doctor if you are taking any of the following medicine such as:
- other
medicines used to reduce anxiety and to induce sleep (such as
midazolam, clonazepam, nitrazepam, nefazodone, fluvoxamine, fluoxetine) - opioid analgesic medications (such as buprenorphine, morphine, codeine or propoxyphene, pethidine, fentanyl etc.)
- other medicines used to manage psychiatric disorders (such as pimozide, haloperidol, risperidone, thioridazine)
- medicines used to manage epilepsy (such as phenytoin, carbamazepine)
- medicines used to manage allergic reactions (such as azelastine, cyproheptadine, mequitazine)
- medicines used to manage fungal infections (such as ketoconazole)
- oral contraceptives (birth control pill) such as ethinylestradiol, drospirenone
- medicines used to manage bacterial infections (such as erythromycin)
- medicines used to manage HIV infection (such as ritonavir, nelfinavir, atazanavir, saquinavir, indinavir)
- general anaesthetic (used to create of loss of consciousness before surgery) such as methoxyflurane and trichloroethylene
- other
medicines used in the management of hypertension and other heart
problems (Ex. nifedipine, nisoldipine, nicardipine, isradipine,
lacidipine, verapamil, diltiazem, hydralazine, clonidine, enalapril,
lisinopril, ramipril, disopyramide, quinidine, amiodarone, isoprenaline,
dobutamine, propafenone and digoxin) - alpha blockers (used to manage hypertension and BPH) Ex. prazosin, doxazosin
- reserpine (an antihypertensive from plant source)
- lignocaine (used to locally numb body parts)
- adrenaline (a medicine that can stimulate the heart)
- ibuprofen and indomethacin (medicine used to relieve pain and inflammation)
- medicines used to manage migraine headaches (Ex. ergotamine, dihydroergotamine or rizatriptan)
- cimetidine, aluminium hydroxide gel (medicine used for stomach problems)
- rifampicin (a medicine used to manage tuberculosis infection)
- theophylline (a medicine used to manage asthma)
- fingolimod (a medicine used to manage multiple sclerosis)
- thyroxine (a medicine used to manage thyroid deficiency)
Overdosage:
If
you or anyone else accidentally took more DIZERAL AZ TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of
overdose might include slow heartbeat, low blood pressure, drowsiness,
confusion, feeling cold, slurred speech, breathing difficulties with
symptoms such as fatigue, hallucinations, tremors, confusion, nausea,
vomiting, body spasms and fainting.
SYNOPSIS
| Drug | :Â Â | Alprazolam, Propranolol |
| Pharmacological Category | :Â Â | Benzodiazepines, Beta-Blockers |
| Therapeutic Indication | :Â Â | Anxiety, Panic attack |
| Dosage Forms | :Â Â | Tablet |
MORE INFORMATION
- Keep DIZERAL AZ TABLET out of reach of children
- Store DIZERAL AZ TABLET at room temperature
FAQs ABOUT DIZERAL AZ TABLET
Q: What is the use of DIZERAL AZ TABLET?
A:
DIZERAL AZ TABLET is used to manage anxiety and panic attacks. It can
also be used to reduce elevated heart rate and blood pressure associated
with anxiety. It is also capable of reducing tremor (shakiness),
restlessness and migraine headache among the affected patients.
Q: How DIZERAL AZ TABLET works in my body?
A:
DIZERAL AZ TABLET suppresses the abnormal electrical activity within
the brain and induces sleep. It also reduces the heart rate and force of
contraction of the heart which, therefore reduces abnormal heart signs
(such as racing heartbeat, nervousness and high blood pressure)
associated with anxiety.
Q: What precautions must be followed while taking DIZERAL AZ TABLET?
A:
Before taking DIZERAL AZ TABLET inform your doctor if you have any
problems in your heart, liver or kidneys. You must also inform your
doctor if you have diabetes, muscle weakness, depression with suicidal
thoughts, any mental illnesses, history of alcoholism or drug abuse or
thyroid problems as a precaution. Avoid consumption of alcohol while
taking this medicine as it may make you feel more dizzy or drowsy. Do
not take DIZERAL AZ TABLET without consulting your doctor if you are
pregnant or breastfeeding. Inform your doctor immediately if you
experience suicidal thoughts or any other unusual changes in behaviour
(such as agitation, restlessness, aggressiveness, irritability, violence
or anger).
Q: Can DIZERAL AZ TABLET cause weight gain?
A:
Yes. Weight gain is one of the common side effects of taking DIZERAL AZ
TABLET. If this side effect bothers you, contact your doctor.
Q: Will DIZERAL AZ TABLET reduce my sex drive?
A:
Yes. DIZERAL AZ TABLET may affect your sexual life. It may decrease sex
drive or cause problems in orgasm, ejaculation or erection. Therefore,
consult your doctor if you experience any such symptoms.
Q: Can DIZERAL AZ TABLET be used in children?
A:
DIZERAL AZ TABLET is not recommended for use in children and
adolescents (aged below 18 years) due to lack of safety data. Therefore,
consult your doctor before taking it.
Q: Can DIZERAL AZ TABLET be used during pregnancy?
A:
DIZERAL AZ TABLET is generally not recommended for use in pregnant
women unless considered necessary by the physician, as it may harm the
growing baby. Therefore, inform your doctor before taking DIZERAL AZ
TABLET if you are pregnant, think you might be pregnant or planning to
have a baby.
Q: Will the use of DIZERAL AZ TABLET cause sleepiness?
A:
Yes, DIZERAL AZ TABLET can make your feel sleepy, drowsy or tired.
Therefore, do not drive or handle heavy machines or tool if you feel
drowsy or sleepy. Avoid consumption of alcohol as it can aggravate your
drowsiness.
Q: Can I consume alcohol while taking DIZERAL AZ TABLET?
A: Avoid consumption of alcohol while taking this medicine as it may make you feel more dizzy or drowsy.
Q: What to do if I forget to take a dose of DIZERAL AZ TABLET?
A:
If you forget to take a dose of DIZERAL AZ TABLET, take it as soon as
you remember. However, if it is time to take the next dose, skip the
missed dose and take the next one at regular times. Do not take a double
dose of DIZERAL AZ TABLET to compensate a missed dose, as it could lead
to toxicity.
Q: Will taking a higher dose of DIZERAL AZ TABLET than the prescribed one be beneficial?
A:
No, taking a higher dose of DIZERAL AZ TABLET will not be effective
rather it can lead to toxicity. Always take the dose prescribed by your
doctor. If the prescribed dose is not effective for you, consult your
doctor for advice. Your doctor might increase the dose or suggest an
alternative therapy.
Q: Can I stop taking DIZERAL AZ TABLET once my symptoms subside?
A:
No. Do not stop taking DIZERAL AZ TABLET without consulting your doctor
even if you feel better during the mid-way of the therapy. Sudden
discontinuation of therapy may cause withdrawal symptoms such as
headaches, muscle pain, tension, restlessness, confusion, mood changes,
difficulty in sleeping and irritability.
Q: Can DIZERAL AZ TABLET be taken daily?
A:
Yes. DIZERAL AZ TABLET can be taken daily as per your doctor’s
instruction. However, if you are doubtful, consult your doctor.
Q: How to take DIZERAL AZ TABLET?
A:
Take DIZERAL AZ TABLET as advised by your physician. Swallow the
medicine with a glass of water. Do not crush or chew the medicine.
Q: What are the common side effects of taking DIZERAL AZ TABLET?
A:
The most common side effects of taking this medicine are depression,
headache, dizziness, drowsiness, forgetfulness, constipation, dry mouth,
decreased sex drive, problems in erection, blurred vision, cold hands
and feet, slow heartbeat and problems in sleeping. Consult your doctor
if any of these side effects trouble you.
Q: What happens if I accidentally take more DIZERAL AZ TABLET?
A:
If you or anyone else accidentally took more DIZERAL AZ TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of
overdose might include slow heartbeat, low blood pressure, drowsiness,
confusion, feeling cold, slurred speech, breathing difficulties with
symptoms such as fatigue, hallucinations, tremors, confusion, nausea,
vomiting, body spasms and fainting.
REFERENCES
1.
KD. Tripathi. Sedative-Hypnotics. Antiadrenergic drugs and Drugs for
Glaucoma. Essentials of Medical Pharmacology. 7th Edition. Page – 405
& 145-151.
2. C L Ravaris, M J Friedman, P J Hauri, G J
McHugo. A controlled study of alprazolam and propranolol in
panic-disordered and agoraphobic outpatients. NIH. National Library of
Medicine. National Center for Biotechnology Information. Pubmed.gov.
December 1991. [Accessed on 25th January 2023]. https://pubmed.ncbi.nlm.nih.gov/1770152/
3.
Pfizer Italia S.r.l. Xanax® 250 microgram and 500 microgram Tablets
alprazolam. Electronic Medicines Compendium. [Revised in November 2022].
[Accessed on 25th January 2023]. https://www.medicines.org.uk/emc/files/pil.1656.pdf
4. Atnahs Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in July 2021] [Accessed on 25th January 2023]. https://www.medicines.org.uk/emc/files/pil.12858.pdf
5. Accord. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed on 25th January 2023]. https://www.medicines.org.uk/emc/files/pil.5853.pdf
6. Leeford Healthcare Pvt Ltd. Prazonal Tablet. [Accessed on 25th January 2023]. https://www.leeford.in/product/779/prazonal
7.
Central Drugs standard Control Organization. Alprazolam Dispersible
Tab. 0.125mg/0.25mg/0.50mg. September 2006. Alprazolam tablets. June
1998. Alprazolam SR 0.5mg tablet. 1997. [Accessed on 25th January 2023].
https://cdscoonline.gov.in/CDSCO/Drugs
| Weight | 17.5 g |
|---|
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