Esiflo 250 Transhaler 1’s
- 13%

Esiflo 250 Transhaler 1’s

Original price was: ₹956.00.Current price is: ₹830.00.

INTRODUCTION ABOUT ESIFLO 250 TRANSHALER

ESIFLO
250 TRANSHALER is a combination of Fluticasone and Salmeterol which
belongs to the group of medicines called Corticosteroids and
Bronchodilators respectively. It is used to manage asthma and chronic
obstructive pulmonary disease (COPD). It also helps in reducing the
flare-ups of COPD symptoms.

Asthma is a long-term respiratory
disease in which your airways become inflamed, swollen and narrowed. It
also causes excessive mucous secretion in the airways  which makes it
difficult for the air to pass through, leading to unpleasant symptoms
like wheezing, difficulty in breathing, chest pain and/or cough.

COPD
is a lung disease characterized by chronic lung inflammation and
obstructed air flow within the airways. It causes wheezing, breathing
difficulties, cough with mucus production and chest pain.

Use
ESIFLO 250 TRANSHALER every day until your doctor tells you to stop. It
is meant for inhalation use only, and therefore do not the swallow the
medicine. Do not stop using this medicine once your symptoms subside
without consulting your doctor. It is suitable for use both in adults
and in adolescents (aged 12 years or above).

ESIFLO 250
TRANSHALER should not be used to relieve a sudden asthma attack (such as
sudden breathing problems). Instead contact your doctor or use a
fast-acting ‘rescue’ inhaler containing salbutamol to subside the
symptoms.

Before using ESIFLO 250 TRANSHALER inform your doctor
if you have any lung infections, liver problems or heart problems. You
must also inform your doctor if you have diabetes, hypertension, fits,
overactive thyroid functions, osteoporosis, adrenal gland problems or a
weak immune system as a precaution.

ESIFLO 250 TRANSHALER should
be used in pregnant and breastfeeding women only if it is considered
necessary by the physician. The most common side effects of using ESIFLO
250 TRANSHALER are headache, cold, oral thrush or oral sores, throat
irritation, hoarse voice, muscle pain and joint pain. Contact your
doctor if any of these side effect worsens.


Esiflo 250 Transhaler 1's

Original price was: ₹956.00.Current price is: ₹830.00.

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SES OF ESIFLO 250 TRANSHALER

It is used to manage, manage the symptoms of:

  • Asthma
  • Chronic Obstructive Pulmonary Disease (COPD)

HOW ESIFLO 250 TRANSHALER WORKS

ESIFLO
250 TRANSHALER is a combination of two medicines namely, fluticasone
and salbutamol. Fluticasone is an inhalation corticosteroid. It blocks
the release of certain chemical messengers in the airways (such as
prostaglandins, leukotrienes) that cause inflammation and swelling.

Salmeterol
is a bronchodilator. It relaxes the smooth muscles of the airways and
widens them. Collectively, they reduce airway inflammation, allows the
air to pass through more freely and makes breathing easier.

DIRECTIONS FOR USE

Use
ESIFLO 250 TRANSHALER medicine every day until your doctor tells you to
stop. It is meant for inhalation only. Inhale the medicine only through
your mouth into the lungs and not via nose.

Follow the instruction given in the enclosed leaflet.

  • prime the device by releasing two puffs of the medicine into the air
  • place the mouthpiece in your mouth between your teeth and ensure completely closure
  • breathe
    in slowly and deeply using your mouth through the mouthpiece while
    simultaneously pressing the top of the canister firmly to release a puff
    of medicine
  • remove the device from your mouth and hold your breath for about 10 seconds or for as long as is comfortable
  • wait about 30 seconds between taking each puff of medicine
  • after inhalation, wipe the mouthpiece with a dry tissue and close the device after use
  • once inhalation is over, rinse your mouth with water and spit it out or brush your teeth

Your
doctor will decide the correct dose, duration and number of puffs for
you depending upon your age, body weight and disease condition.

 Do
not start using this medicine unless your doctor or health care
provider has taught you how to use and you understand how to use it
correctly. If you find it difficult to use this device, your doctor may
recommend you a suitable spacer device.

Do not stop taking this
medicine abruptly or reduce the dose without consulting your doctor, as
it could make your breathing even worse.

SIDE EFFECTS OF ESIFLO 250 TRANSHALER

COMMON

  • headache
  • common cold
  • thrush in the mouth or throat (a yeast infection that causes sore, creamy-yellow, raised patches)
  • sore tongue, hoarse voice, throat irritation
  • muscle pain or cramps
  • joint pain and swelling
  • bruising and fractures
  • inflammation of sinuses
  • signs of low levels of potassium in blood (such as an uneven heartbeat, muscle weakness or cramps)

UNCOMMON

  • diabetes (increased blood sugar levels)
  • cataract (cloudy eyes)
  • unusually fast or uneven heartbeat, tremor (feeling shaky)
  • chest pain
  • feeling worried, disturbance in sleep
  • allergic skin rash

RARE

  • slowing of growth in adolescents, bone thinning, glaucoma, weight gain
  • Cushing’s Syndrome (a disorder caused due to release of high levels of cortisol)
  • changes in behavior (such as being unusually active and irritable)
  • fungal infection in the esophagus which causes difficulties in swallowing

Stop using ESIFLO 250 TRANSHALER and contact your doctor immediately if you experience any of the following side effects:

  • severe
    allergic reactions (such as sudden wheezing, cough, shortness of
    breath, skin rash, itching, swelling of the face, lips, tongue, or
    throat, breathing difficulties, sudden fast heartbeat which can cause
    fainting, light-headedness, collapse or even loss of consciousness)
  • sign
    of pneumonia (a lung infection accompanied with fever, chills,
    increased cough production, increased breathing difficulties, excessive
    mucus production and change in mucus color)

HOW TO MANAGE SIDE EFFECTS

Headache:  

Rest
and relax. Drink plenty of fluids such as water or electrolytes. Apply a
pain-relieving balm on the head if required. Do not consume too much of
alcohol. Consult your doctor if the symptom did not improve.

Throat irritation:

Gargle
your throat with salt water twice a day. Always try to drink warm
water. Avoid chilled, cooled, or sweetened food items or beverages.
Drinking turmeric milk or ginger tea mixed with honey and pepper powder
can ease the soreness. Consult your doctor if the symptom did not
improve.

Muscle pain or cramps:

Rub a
pain-relieving balm or place a heat pack on the affected area for some
time, as it could ease the pain. Do not move the affected area
frequently. Try to do some simple movements every day which would
improve blood circulation and reduce further incidence of muscle pain.
Try to eat a well-balanced protein rich diet, so that it can help to
repair and rebuild the damaged muscle. Consult your doctor if the
symptom did not improve.

Joint pain:

Rub a
pain-relieving balm or place a heat pack on the affected area for some
time, as it could ease the pain. Do not move the affected area
frequently. Consume calcium and vitamin supplements regularly,
particularly if you are elderly. Consult your doctor if the symptom did
not improve.

Allergic skin rash:

Avoid
hot showers because hot water can irritate your skin further. Do not
scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. Consult your doctor if the symptom did
not improve.

WARNING & PRECAUTIONS

PREGNANCY

ESIFLO
250 TRANSHALER should be used in pregnant women only if it is
considered necessary by the doctor. Your doctor may prescribe this
medicine after outweighing the risk and benefits to you and your baby.
Therefore, inform your doctor before using it.

BREASTFEEDING

ESIFLO
250 TRANSHALER should be used in breastfeeding women only if it is
considered necessary by the doctor. Therefore, consult your doctor for
advice before using it.

DRIVING AND USING MACHINES

Do not drive or operate any heavy tools or machines if your ability is affected by ESIFLO 250 TRANSHALER.

LIVER

ESIFLO
250 TRANSHALER should be taken with caution in patients with liver
diseases. Therefore, consult your doctor before using it.

ALLERGY

Do not use ESIFLO 250 TRANSHALER if you are allergic to Salmeterol or Fluticasone.

LUNGS

ESIFLO
250 TRANSHALER should be taken with caution among patients who have or
previously had any Tuberculosis or any other lung infections. Therefore,
consult your doctor before using it.

HEART DISEASE

ESIFLO
250 TRANSHALER should be taken with caution in patients with heart
diseases (such as irregular or fast heartbeat). Therefore, consult your
doctor before using it.

OTHERS

ESIFLO 250 TRANSHALER is not recommended for use in patients having:

  • status asthmaticus (respiratory failure)
  • acute asthma attacks

Before using ESIFLO 250 TRANSHALER, inform your physician if you:

  • have an over-active thyroid gland
  • have diabetes
  • have high blood pressure
  • have hypokalemia (low levels of potassium in blood)
  • have fits (seizure)
  • have osteoporosis (weak bones)
  • have a weak immune system
  • have or had eye problems (such as glaucoma, increased pressure in the eyes, cataracts)
  • have viral, bacterial or fungal infections (Ex. measles, chickenpox)
  • have glucose intolerance
  • have problems in adrenal gland (Ex. adrenal insufficiency)
  • met with any major trauma (accidents) or undergone a surgery

Use in pediatrics:

ESIFLO
250 TRANSHALER is not recommended for use in children younger than 12
years of age. Kindly consult your doctor before using it.

Use in geriatrics:

ESIFLO
250 TRANSHALER should be taken with caution in elderly patients (aged
65 years or above). Therefore, consult your doctor before using it.
Proper dose adjustments and careful monitoring are required in such
patients.

INTERACTIONS

A. Drug-Drug interactions:

Before using ESIFLO 250 TRANSHALER, inform your physician if you are taking any of the following medicines such as:

  • other beta-blockers (used to manage high blood pressure or other heart conditions) Ex. atenolol, propranolol and sotalol
  • medicines used to manage fungal infection (such as ketoconazole and itraconazole)
  • medicines used to manage HIV infection (Ex. ritonavir, atazanavir, indinavir, nelfinavir, saquinavir or cobicistat)
  • clarithromycin, erythromycin (used to manage bacterial infections)
  • other corticosteroids (taken orally or via injections to manage pain or inflammation) Ex. dexamethasone
  • potassium-sparging diuretics (used to manage high blood pressure by increasing urine output) Ex. spironolactone, acetazolamide
  • other medicines that can cause bronchodilation (such as salbutamol, formoterol)
  • xanthine medicines (used to manage asthma) Ex. theophylline and aminophylline
  • nefazodone (used to manage depression)
  • medicines
    used to manage depression such as (rasagiline, selegiline, phenelzine,
    amitriptyline, nortriptyline, doxepin, imipramine, desipramine)

Overdosage:

If
you or anyone else accidentally inhaled excessive amount of this
medicine, contact your doctor immediately or go to the hospital straight
away. Symptoms of overdosage might include shortness of breath, chest
pain, fast heartbeat, feeling shaky, dizziness, headache, muscle
weakness and joint pain.

SYNOPSIS

Drug :   Fluticasone, Salmeterol
Pharmacological Category :   Corticosteroids, Beta-1 receptor agonists
Therapeutic Indication :   Asthma, COPD
Dosage Forms :   Autohaler,
Blisters, Capsule, Inhalation capsule, Octacaps, Respicaps, Rotacaps,
Trans caps, Nexcaps, Accuhaler, Inhaler, Ciphaler, Multihaler

MORE INFORMATION

  • Keep ESIFLO 250 TRANSHALER out of reach of children
  • Store ESIFLO 250 TRANSHALER at room temperature

FAQs ABOUT ESIFLO 250 TRANSHALER

What is the use of ESIFLO 250 TRANSHALER?

ESIFLO
250 TRANSHALER is used to manage asthma and chronic obstructive
pulmonary disease (COPD). It also helps in reducing flare-ups of COPD
symptoms.

How ESIFLO 250 TRANSHALER works in my body?

ESIFLO
250 TRANSHALER relaxes the smooth muscles of the airways and widens
them. It also reduces the inflammation of airway tract. Therefore, it
allows the air to pass through more freely and makes breathing easier.

Can ESIFLO 250 TRANSHALER be used on an asthma attack?

ESIFLO
250 TRANSHALER is only used to manage or manage the symptoms of asthma
and COPD (such as breathlessness or wheezing). If your asthma or
breathing gets worse suddenly, contact your doctor immediately or go to
the straight away to avoid further exacerbation of the attack. Meanwhile
use a fast-acting rescue inhaler containing salbutamol along with this
medicine.

Is ESIFLO 250 TRANSHALER safe?

ESIFLO 250 TRANSHALER is considered safe at doses prescribed by the physician.

What are the side effects of using ESIFLO 250 TRANSHALER?

The
most common side effects of using ESIFLO 250 TRANSHALER are headache,
cold, oral thrush or oral sores, throat irritation, hoarse voice, muscle
pain and joint pain. Contact your doctor if any of these side effect
worsens.

Can I stop using ESIFLO 250 TRANSHALER once my symptoms subside?

No.
Use ESIFLO 250 TRANSHALER every day until your doctor tells you to
stop. Do not stop taking this medicine abruptly or reduce the dose
without consulting your doctor, as it could make your breathing even
worse. Your doctor will access your disease condition regularly and will
increase or decrease the dose accordingly.

Will ESIFLO 250 TRANSHALER more effective if taken at higher doses?

Always
consume the dose prescribed for you by your physician. Your doctor will
decide the correct dose and duration of therapy for you depending upon
your age, body weight and severity of the disease. Do not take a higher
dose of this medicine without consulting your doctor as it could lead to
unwanted side effects. It your symptoms are not relieved by the
prescribed dose, consult your doctor so that he might adjust the dose
according to your health condition or can suggest an alternative
therapy.

I’m pregnant. Can I use ESIFLO 250 TRANSHALER?

ESIFLO
250 TRANSHALER should be used in pregnant women only if it is
considered necessary by the physician. Your doctor will prescribe you
with ESIFLO 250 TRANSHALER after evaluating the risks and benefits of
the therapy.

Can ESIFLO 250 TRANSHALER be used in children?

ESIFLO
250 TRANSHALER is considered safe for use in children and adolescents
aged 12 years or above. However, it is not recommended for use in
children younger than 12 years due to lack of safety data. Kindly
consult your doctor before taking.

How long will it take for ESIFLO 250 TRANSHALER to relieve the symptoms and how long the effects can last?

Generally,
ESIFLO 250 TRANSHALER takes about 10-15 minutes to relieve the symptoms
of asthma or COPD. However, the onset of action slightly differs from
person to person based upon their disease condition. The effects of
ESIFLO 250 TRANSHALER can last for 12-18 hours, because salmeterol
present in this medicine is considered as a longer-acting beta-1
adrenergic agonist.

Can ESIFLO 250 TRANSHALER cause infection in the mouth?

Yes. ESIFLO 250 TRANSHALER may cause fungal
infections of the mouth (oral thrush). To avoid this, make sure to
rinse your mouth with water after inhaling the medicine. However, if an
infection develops, consult your doctor.

What happens when you forget to use ESIFLO 250 TRANSHALER?

If
you forget to use ESIFLO 250 TRANSHALER, use it as soon as you
remember. However, if it’s time for the next dose, skip the missed dose
and take the next dose. Do not use a double dose to compensate the
missed dose.

Can ESIFLO 250 TRANSHALER be used if you have an infection?

Inform
your doctor if you have any bacterial, fungal, or viral infection
before using ESIFLO 250 TRANSHALER. Your doctor will evaluate your
existing health condition and advise changes in management accordingly.
Also, inform your doctor if have exposure to an infectious environment
or with a person with infectious diseases, as ESIFLO 250 TRANSHALER may
mask your symptoms of the infection.

REFERENCES

1.
KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of
medical pharmacology. Seventh edition. 2013. Page – 221-224 &
230-233

2. Jinming Gao and Roy A Pleasants. Role of the fixed
combination of fluticasone and salmeterol in adult Chinese patients with
asthma and COPD. NCBI; PMC US National Library of Medicine, National
Institute of Health. April 2015. [Accessed 10th January 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403740/

3.
Cipla Ltd. SEROFLO Inhaler (Salmeterol + Fluticasone propionate).
Ciplamed.com. [Revised in March 2020] [Accessed 10th January 2022] https://www.ciplamed.com/content/seroflo-inhaler

4. Cipla (EU) limited. Electronic Medicines Compendium (EMC). [Revised in February 2019] [Accessed 10th January 2022] https://www.medicines.org.uk/emc/files/pil.10146.pdf

5. Glaxo Wellcome Production. Health Products Regulatory Authority (HPRA). [Revised in March 2018] [Accessed 10th January 2022] https://www.hpra.ie/img/uploaded/swedocuments/PIL-2206316-02052018155014-636608730177031250.pdf

6. Orion Corporation. Electronic Medicines Compendium (EMC). [Revised in March 2018] [Accessed 10th January 2022] https://www.medicines.org.uk/emc/files/pil.9224.pdf

7.
Cipla Ltd. SEROFLO Inhaler (Salmeterol + Fluticasone propionate).
Ciplamed.com. [Revised in March 2020]. [Accessed on 16th November 2022] https://www.ciplamed.com/content/seroflo-inhaler

8.
Central Drugs Standard Control Organization. Fluticasone Propionate
50mcg/125mcg/250mcg + Salmeterol xinafoate 25mcg/25mcg/25mcg Powder for
inhalation. Salmeterol xinafoate + fluticasone propionate. [Accessed on
16th November 2022] https://cdscoonline.gov.in/CDSCO/Drugs


Weight 40 g

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