- 10%
GRASTIM 300 Injection 1ml
Original price was: ₹689.08.₹621.00Current price is: ₹621.00.
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Introduction About GRASTIM 300 INJECTION
GRASTIM 300 INJECTION contains Filgrastim which belongs to the group of medicines called Cytokines. GRASTIM 300 INJECTION is used to increase the number of white blood cells to manage infections after chemotherapy management and bone marrow transplant. GRASTIM 300 INJECTION is also used before high-dose chemotherapy to make the bone marrow produce more stem cells after management. It is also used to manage infections in patients suffering from severe chronic neutropenia (rare blood disorder marked by abnormal white blood cell levels). The medicine is also indicated for use to reduce the risk of infections in patients with advanced HIV infection.
GRASTIM 300 INJECTION is not recommended for use in patients allergic to Filgrastim. It is also not recommended for use in patients suffering from hereditary fructose intolerance (rare genetic disorder marked by inability of the body to break down fructose). Before receiving GRASTIM 300 INJECTION, inform your doctor if you suffer from sickle cell anemia (inherited blood disorder), osteoporosis (condition marked by weak and gentle bones), and/or have kidney/liver problems.
GRASTIM 300 INJECTION is generally not recommended for use in pregnant and breastfeeding women. It should be used with caution in children and adolescents (aged below 18 years) and in elderly patients (aged 65 years and above) after consulting the doctor. The most common side effects of receiving GRASTIM 300 INJECTION are anemia, headache, decreased appetite, nausea, vomiting, constipation, diarrhea, and/or unusual hair loss. Consult your doctor if any of these symptoms worsens.
Uses Of GRASTIM 300 INJECTION
- Increases white blood cell count after chemotherapy management and bone marrow transplant to manage infections in affected individuals
- Mange infections in patients suffering from severe chronic neutropenia
- Helps to reduce risk of infections in patients with advanced HIV infection
How GRASTIM 300 INJECTION Works
GRASTIM 300 INJECTION works by stimulating the bone marrow to produce more neutrophils (type of white blood cell) which helps in fighting the microorganisms and manage the occurrence of infection after chemotherapy/bone marrow transplant in affected individuals.
How to use GRASTIM 300 INJECTION
GRASTIM 300 INJECTION will be given to you only by a doctor or a nurse into the skin as a subcutaneous injection or into the vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of GRASTIM 300 INJECTION
Common
- Thrombocytopenia (reduced ability of blood to clot)
- Anemia
- Headache
- Decreased appetite, nausea, vomiting, constipation, diarrhea
- Unusual hair loss/thinning
- Pain, general weakness/feeling unwell, tiredness, fever, muscle spasm
- Mucosal inflammation (soreness and swelling of the digestive tract)
- Signs of bronchitis (inflammation of the lung) such as cough, shortness of breath, chest discomfort
- Oral pain, nose bleeds, upper respiratory tract infection, chest pain
- Urinary tract infection
- Sleeplessness, dizziness
- Hypoesthesia (decreased feeling of sensitivity especially in the skin)
- Tingling/numbness and swelling in hands and feet
- Low/high blood pressure
- Cough
- Pain in mouth and throat
- Rash, redness of skin
- Dysuria (pain when passing urine)
Uncommon
- Allergic reaction (hypersensitivity)
- Rejection of transplanted bone marrow
- Liver damage caused by blocking of the small veins within the liver
- Respiratory failure (impaired lung function) causing breathlessness
- Pulmonary oedema (swelling and/or fluid in the lungs)
- Inflammation of the lungs
- Bleeding from the lung (pulmonary haemorrhage)
- Hypoxia (lack of absorption of oxygen in the lung)
- Bumpy skin rash (rash maculo-papular)
- Osteoporosis (disease which causes bones to become less dense, making them weaker, more brittle and likely to break)
- Injection site reaction
Rare
- Signs of sickle cell anemia such as severe pain in the bones, chest, gut, and/or joints
- Anaphylactic reaction (sudden life-threatening allergic reaction)
- Pseudogout (pain and swelling of the joints)
- Fluid volume disturbances
- Cutaneous vasculitis (inflammation of the blood vessels in the skin)
- Plum-colored, raised, painful sores on the limbs and sometimes the face and neck with a fever (Sweets syndrome)
- Worsening of rheumatoid arthritis (joint inflammation)
- Inflammation of aorta
Stop receiving GRASTIM 300 INJECTION and contact your doctor immediately if you experience any of the following side effects:
- Signs of an allergic reaction such as weakness, drop in blood pressure, difficulty breathing, swelling of the face/lips/mouth/tongue/throat, shortness of breath, red itchy welts, and/or rash
- Signs of acute respiratory distress syndrome (condition that occurs due to accumulation of fluid in air sacs) such as cough, fever, and/or difficulty in breathing (dyspnoea)
- Signs of glomerulonephritis (kidney injury) such as puffiness in your face/ankles, blood in urine/brown-coloured urine, and/or low urine output
- Signs of capillary leak syndrome (condition that occurs due to blood leakage from small blood vessels into body) such as swelling/puffiness associated with low urine output, difficulty breathing, abdominal swelling, feeling of fullness, and/or general feeling of tiredness
- Signs of sepsis (blood poisoning) such as fever, shivering, feeling very cold, high heart rate, confusion/disorientation, shortness of breath, extreme pain/discomfort, and/or clammy/sweaty skin
- Enlarged/ruptured spleen associated with symptoms such as left abdominal pain, pain below the left rib cage, and/or pain at the tip of shoulder
- Blood in urine (haematuria)
- Signs of thrombocytopenia (decreased blood platelet count) such as unusual bleeding/bruising
- Signs of aortitis (inflammation of aorta) such as fever, abdominal pain, malaise, and/or back pain
How To Manage Side Effects
Constipation
Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise such as going for a daily walk or run). If this does not help, consult and inform your doctor for receiving alternate managements for constipation.
Diarrhea
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptom worsens.
Headache
If GRASTIM 300 INJECTION causes headache, then take rest and drink plenty of fluids. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of receiving GRASTIM 300 INJECTION. If it lasts more than a week or becomes severe, inform your doctor.
Nausea And Vomiting
Receive GRASTIM 300 INJECTION with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.
Warning & Precautions
Pregnancy
Contraindicated
GRASTIM 300 INJECTION is generally not recommended for use during pregnancy. Consult your doctor before receiving GRASTIM 300 INJECTION.
Breastfeeding
Contraindicated
GRASTIM 300 INJECTION is generally not recommended for use in breastfeeding women. Consult your doctor before receiving GRASTIM 300 INJECTION.
Driving and Using Machines
Use with Caution
Do not drive/operate machines if you feel dizzy after receiving GRASTIM 300 INJECTION.
Kidney
Use with Caution
GRASTIM 300 INJECTION should be used with caution in patients with kidney problems such as renal impairment. Consult your doctor before receiving the medicine.
Liver
Use with Caution
GRASTIM 300 INJECTION should be used with caution in patients with liver problems such as hepatic impairment. Consult your doctor before receiving the medicine.
Allergy
Contraindicated
GRASTIM 300 INJECTION is not recommended for use if you are allergic (hypersensitive) to Filgrastim, and/or any other ingredients of this medicine.
Use In Pediatrics
Use with Caution
GRASTIM 300 INJECTION should be used with caution in children and adolescents (aged below 18 years). Consult your doctor before GRASTIM 300 INJECTION is administered to the child.
Use In Geriatrics
Use with Caution
GRASTIM 300 INJECTION should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before receiving GRASTIM 300 INJECTION.Â
| Weight | 25 g |
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