Hansepran 50mg Capsule 10’S
- 13%

Hansepran 50mg Capsule 10’S

Original price was: ₹23.00.Current price is: ₹20.00.

*10 Capsule(s) in a Strip
* Country of Origin: India
* Delivery charges if applicable will be applied at checkout


Hansepran 50mg Capsule 10'S

Original price was: ₹23.00.Current price is: ₹20.00.

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SKU: pr/med/423 Category:

INTRODUCTION

HANSEPRAN
50MG contains Clofazimine which belongs to the group of medicines
called Antimycobacterial agents. It is used to manage lepromatous
leprosy (including dapsone-resistant lepromatous leprosy and lepromatous
leprosy complicated by erythema nodosum leprosum) in combination with
other anti-leprosy drugs.

Leprosy is a chronic and contagious
infection caused by mycobacterium leprae which affects the skin, nerves
outside the brain and spinal cord including upper respiratory tract’s
mucosa, and eyes. It is generally characterized by symptoms such as
discoloured skin patches with loss of sensations, numbness or tingling
sensation (in hands, feet, arms and legs), painless wounds/burns
(typically on hands and feet) and muscle weakness.

HANSEPRAN 50MG
is not recommended for use if you have a personal or family history of
heart disease such as congenital long QT syndrome (a type of hereditary
heart disease). It should be used with caution in patients with frequent
stomach pain, continuous vomiting or diarrhoea, hepatitis B or C (liver
infection), liver, kidney or other heart problems. HANSEPRAN 50MG
should be used with caution in pregnant women and it is not recommended
for use in breastfeeding women.

HANSEPRAN 50MG is recommended for
use in children and adolescents (aged 10 to 14 years) and it should be
used with caution in children (aged below 10 years). Also, it should be
used with caution in elderly patients (aged 65 years and above). Consult
your doctor before taking HANSEPRAN 50MG. The common side effects
associated with the use of HANSEPRAN 50MG are reversible reddish
dark-brown discolouration of skin, hair and eyes, discolouration of body
fluids (such as sweat, saliva, tears, urine, and stools), abdominal
pain, diarrhoea, nausea, vomiting and dryness of skin. Consult your
doctor if any of the symptom worsens.

USES OF HANSEPRAN 50MG

Used in combination with other anti-leprosy drugs to manage:

  • lepromatous leprosy
  • dapsone-resistant lepromatous leprosy
  • lepromatous leprosy complicated by erythema nodosum leprosum

HOW HANSEPRAN 50MG WORKS

HANSEPRAN
50MG induces membrane dysfunction in the bacterial cell which also
works by blocking the production of certain cells (responsible for
causing inflammation) in the body that results in destruction of
bacterial cell and prevention of inflammatory reaction in the body thus
helps to manage lepromatous leprosy and its associated symptoms.

DIRECTIONS FOR USE

Take
HANSEPRAN 50MG as advised by your physician. Swallow the medicine with a
glass of water. Do not crush or chew the medicine. Your doctor will
decide the correct dose and duration for you depending upon your age,
body weight and disease condition.

SIDE EFFECTS OF HANSEPRAN 50MG

COMMON

  • discolouration of lining of the eyelids and body fluids such as sweat, sputum, saliva, tears, urine and stools
  • reversible reddish/pink to dark brown, black discolouration of the skin, hair and eyes
  • upper abdominal pain
  • diarrhoea
  • nausea
  • vomiting
  • food intolerance
  • scaling and dryness of skin
  • rashes
  • itching
  • pigmentation in eyes
  • dryness, burning, itching or irritation in eyes
  • high blood sugar levels
  • signs of elevated erythrocyte sedimentation rate (ESR) such as increased frequency of infections
  • disturbed eyesight
  • weight loss

UNCOMMON

  • headache
  • loss of appetite
  • increased skin sensitivity to sunlight
  • skin reactions such as acneiform eruptions (condition marked by acne like bumps eruption)
  • tiredness
  • swollen lymph nodes
  • dizziness
  • constipation
  • jaundice (yellowish discoloration of the eyes and skin)
  • fever
  • erythroderma (inflammation of skin surface)
  • monilial cheilosis (fungal infection at the angles of the mouth)
  • anorexia (an eating disorder causing weight gain or weight loss)
  • eosinophilic enteritis (rare inflammatory disorder of intestinal wall)
  • maculopathy (an eye disorder)
  • drowsiness
  • giddiness
  • neuralgia (pain at path of the nerve)
  • taste disturbance
  • splenic infarction (impaired blood supply to spleen)
  • thromboembolism (blood clots causing blockage in blood vessels)
  • anaemia (reduced blood cell count)
  • cystitis (inflammation of urinary bladder)
  • bone pain
  • oedema (swelling in hands and feet caused by water retention)
  • signs of vascular pain such as heaviness/pain in the vascular disease/injury area

RARE

Stop taking HANSEPRAN 50MG and contact your doctor if you experience any of the following side effects:   

  • skin rash
  • signs of liver damage such as severe nausea, vomiting, abdominal pain, bloody or black tarry stools and yellow eyes or skin
  • signs of heart rhythm disturbances such as irregular heartbeat, dizziness, fainting, shortness of breath and severe tiredness
  • upper stomach pain accompanied by fever, chills, chest, left shoulder pain, nausea and vomiting
  • blurred or cloudy vision
  • bowel obstruction 
  • signs of bleeding in stomach and intestine such as black stools
  • signs of hepatitis such as feeling unwell, nausea, vomiting, a loss of appetite, and fever
  • serious skin reactions such as flaking and peeling of skin
  • severe dryness, burning, itching, or irritation in eyes
  • severe eyesight problems
  • severe skin rash and itchiness
  • extreme weight loss
  • depression due to skin discoloration

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink
lot of fluids, such as water to keep yourself hydrated. Try to avoid
taking any medicine on your own to manage diarrhoea and consult your
doctor if the symptom gets worse.

Nausea and vomiting:

Try
to take HANSEPRAN 50MG with or just after a meal or a snack. Stick to
simple meals. Avoid eating oily, fried or spicy foods. Consult your
doctor if the symptom gets worse.

Itchy Skin:

Try
to pat or tap your skin instead of scratching it. Hold a damp towel to
cool your skin. Wear loose clothing and avoid tight clothes, or clothes
made from wool or synthetic fabrics. Avoid using perfumed soaps,
deodorants or moisturizers and use a skin softener regularly. Consult
your doctor if the symptom gets worse.

Headache:

Apply
hot or cold-water bag on your head. Try taking rest in a quiet and dark
room. Apply pain relieving balm on your forehead if necessary. Drink
sufficient amount of fluids and avoid skipping meals. Consult your
doctor if the symptom does not improve.

Constipation:

Take
fiber rich foods in your diet such as fresh fruits, vegetables and
whole grain cereals and drink plenty of fluids. Exercise more regularly
and stay active. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

HANSEPRAN
50MG should be used with caution in pregnant women and in women
planning for pregnancy only if it is considered clearly necessary.
Consult your doctor before taking HANSEPRAN 50MG.

BREASTFEEDING

HANSEPRAN
50MG is not recommended for use in breastfeeding women as it may pass
through milk. Consult your doctor before taking HANSEPRAN 50MG.

DRIVING AND USING MACHINES

Do
not drive or operate any machines while taking HANSEPRAN 50MG as this
medicine can cause dizziness, tiredness, headache and/or eyesight
problems. Consult your doctor before taking HANSEPRAN 50MG.

KIDNEY

HANSEPRAN 50MG should be used with caution in patients with kidney problems. Consult your doctor before taking HANSEPRAN 50MG.

LIVER

HANSEPRAN
50MG should be used with caution in patients with liver problems such
as hepatitis B or C (liver infection). Consult your doctor before taking
HANSEPRAN 50MG.

ALLERGY

HANSEPRAN
50MG is not recommended for use if you are allergic to clofazimine,
peanuts, soya, or any other ingredients of this medicine.

HEART DISEASE

HANSEPRAN
50MG is not recommended for use if you have a personal or family
history of heart problem such as congenital long QT syndrome (heart
rhythm disorder). It should be used with caution in patients with other
heart problems. Consult your doctor before taking HANSEPRAN 50MG.

OTHERS

Before taking HANSEPRAN 50MG, inform your doctor if you have:    

  • frequent stomach pain
  • continuous diarrhoea or vomiting

Use in Paediatrics:

HANSEPRAN
50MG is recommended for use in children and adolescents (aged 10 to 14
years). It should be used with caution in children (aged below 10 years)
after consulting the doctor who might decide the dosage based on
child’s age, body weight and disease condition.

Use in Geriatrics:

HANSEPRAN
50MG should be used with caution in elderly patients (aged 65 years or
above). Consult your doctor before taking HANSEPRAN 50MG.

INTERACTIONS

A. Drug-Drug Interactions

Before taking HANSEPRAN 50MG, inform your doctor, if you are taking any of the following medicines:

  • other medicines used to manage leprosy Ex. dapsone
  • medicines used to manage tuberculosis and leprosy Ex. rifampicin, isoniazid, bedaquiline and delamanid
  • azithromycin, clarithromycin and fluoroquinolones such as levofloxacin (used to manage bacterial infections)
  • amprenavir,
    delaviridine, efavirenz, etravirine, indinavir, nelfinavir,
    raltegravir, rilpivirine, simeprevir, maraviroc (used to manage HIV
    infection)
  • medicines to lower blood cholesterol levels Ex. simvastatin, lovastatin
  • medicines
    used to manage high blood pressure Ex. losartan, verapamil, diltiazem,
    nitrendipine, amlodipine, nislodipine, nifedipine, eplerenone,
    felodipine, lercanidipine
  • medicines to reduce blood sugar levels Ex. pioglitazone, repaglinide, saxagliptin
  • phenytoin, fosphenytoin (used to control seizures)

Overdosage:

If
you or anyone else accidentally takes too much of HANSEPRAN 50MG,
consult your doctor immediately or visit the nearby hospital if you
experience any unusual symptoms.


Weight 17.5 g

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