NTRODUCTION ABOUT HISONE 5MG TABLET
HISONE 5MG TABLET
contains Hydrocortisone which belongs to the group of medicines called
Corticosteroids. HISONE 5MG TABLET is used as a replacement therapy to
replace insufficient adrenal hormone in the body that occurs due to
inactive/underactive adrenal gland in affected individuals.
HISONE
5MG TABLET is also used to inhibit adrenocorticotropic hormone
(chemical messenger responsible to regulate cortisol) when taken in
combination with aminoglutethimide medicine for breast and prostate
cancer. The medicine is also used to manage few types of illness and
replace insufficient adrenal hormone after injury, surgery and/or other
stressful events.
HISONE 5MG TABLET is not recommended for use in
patients allergic to hydrocortisone, certain foods, preservatives
and/or dyes. It is also not recommended for use in patients with fungal
infections (such as thrush, candida) and in patients who recently
received/scheduled (for) vaccinations.
Before taking HISONE 5MG
TABLET, inform your doctor if you have/ever had severe depression, manic
depression, septicaemia (life threatening infection), stomach ulcer,
chicken pox/shingles, weakened immune system, high blood pressure, heart
problems (such as heart attack, congestive heart disease), kidney
and/or liver problems.
HISONE 5MG TABLET should be used with
caution in pregnant and breastfeeding women only if it is clearly
necessary. It is also used with caution in children and adolescents
(aged below 18 years). The medicine can also be indicated for use in
elderly patients (aged above 65 years) after consulting the doctor.
The common side effect of taking HISONE 5MG TABLET is mental health problem. Consult your doctor if the symptom worsens.
USES OF HISONE 5MG TABLET
- As
a replacement therapy to replace insufficient adrenal hormone in the
body (that occurs due to inactive/underactive adrenal gland) - Inhibits
adrenocorticotropic hormone (chemical messenger responsible to regulate
cortisol) when taken in combination with aminoglutethimide medicine for
breast and prostate cancer - Manage few types of illness and
replace insufficient adrenal hormone after injury, surgery and/or other
stressful events in affected individuals
HOW HISONE 5MG TABLET WORKS
HISONE
5MG TABLET works by replacing insufficient cortisol (naturally produced
steroid) levels and blocks the production of certain chemical
messengers (responsible for inflammation and allergies) in the body
which results in decreased swelling and providing relief from
inflammation and pain in affected individuals.
DIRECTIONS FOR USE
Take
HISONE 5MG TABLET as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. Your doctor
will decide the correct dose and duration for you depending upon your
age, body weight and disease condition.
SIDE EFFECTS OF HISONE 5MG TABLET
COMMON
- mental health problems
RARE
- palpitations (racing/pounding heartbeat)
Stop taking HISONE 5MG TABLET and contact your doctor if you experience any of the following side effects:
- signs
of severe allergic reaction such as difficulty in breathing, wheezing,
shortness of breath, swelling of face/tongue/lips/other parts of the
body, red itchy welts, rash, itching - feeling depressed (including thinking about suicide), irritable and anxious
- fluctuating mood and sleep disturbance, feeling/seeing/hearing non existing things
- having difficulty in thinking/being confused and experiencing loss of memory
- infections such as fungal/viral (including herpes)
- development of Cushingoid facies (round/moon-shaped face)
- increased blood sugar level
- signs of salt and water retention such as swelling and raised blood pressure
- increased appetite and weight gain
- worsening of seizures
- sleepiness, dizziness/spinning sensation, headache
- changes
in vision due to cataract (clouding of eye lens), glaucoma (increased
pressure withing the eye), blurred vision, dry eyes, thinning of eye
surface, worsening of existing eye infections - high blood pressure, formation of blood clots
- gastrointestinal symptoms such as indigestion, stomach/food-pipe ulcers, bloating and/or abdominal pain
- skin-related symptoms such as slow healing of wounds/cuts, acne, bruising, stretch marks, spider veins and/or excessive hair
- bone,
muscle and joints symptoms such as muscle weakness, joint swelling
and/or bone thinning (which can lead to fractured/broken bones) - irregular/lack of menstrual periods
- general feeling of being unwell and tiredness
- signs of pseudotumourcerebri (increased pressure within the skull) in children such as headaches with vomiting, drowsiness
- signs of bleeding ulcers such as stomach pain, bleeding from back passage, black stools/vomiting with blood
- signs
of pancreatitis (inflammation of pancreas) such as abdominal pain, low
blood pressure, loss of consciousness and/or decreased output of urine - signs of thromboembolism (blood clot in the lung) such as sudden shortness of breath, chest pain and/or coughing up blood
- signs of bleeding ulcers in the stomach such as black stool along with vomiting with blood
- signs
of heart failure such as swollen ankles, chest pain, difficulty in
breathing & palpitations, irregular heartbeats, irregular /few/rapid
pulse, high blood pressure - signs of aseptic necrosis (necrosis
of bone) such as broken bones/fractures, breakdown of bone, joint
inflammation in the knee & groin and/or torn tendons
WARNING & PRECAUTIONS
PREGNANCY
HISONE
5MG TABLET should be used with caution during pregnancy only if it is
clearly necessary. Inform your doctor immediately if you get pregnant
while taking this medicine. Consult your doctor before taking HISONE 5MG
TABLET.
BREASTFEEDING
HISONE
5MG TABLET should be used with caution in breastfeeding women only if
it is necessary since the medicine may pass through breastmilk. Consult
your doctor before taking HISONE 5MG TABLET.
DRIVING AND USING MACHINES
Do
not drive or operate machines if you experience extreme tiredness,
short lasting dizziness, changes in eyesight (such as blurred vision)
and/or muscle weakness after taking HISONE 5MG TABLET.
KIDNEY
HISONE
5MG TABLET should be used in caution in patients with kidney problems.
Consult your doctor before taking HISONE 5MG TABLET.
LIVER
HISONE
5MG TABLET should be used in caution in patients with liver problems.
Consult your doctor before taking HISONE 5MG TABLET.
ALLERGY
Do
not take HISONE 5MG TABLET if you are allergic to hydrocortisone,
certain foods, preservatives, dyes and/or any ingredients of this
medicine.
HEART DISEASE
HISONE
5MG TABLET should be used with caution in patients with heart problems
such as heart attack and congestive heart disease. Consult your doctor
before taking the medicine.
OTHERS
HISONE 5MG TABLET is not recommended for use if you:
- have fungal infections such as thrush, candida and/or any other infections
- have been vaccinated recently and/or schedule to receive any vaccine
Before taking HISONE 5MG TABLET, inform your doctor if you:
- have/ever had severe depression and/or manic depression (bipolar disorder)
- have/had septicaemia (life threatening infection), tuberculosis
- have stomach ulcer and/or other digestive problem
- have chicken pox/shingles
- come
in contact with people (who have chicken pox, shingles and/or measles)
especially if you have not already had these illnesses - have a weakened immune system
- have a herpes eye infection (type of viral infection)
- had muscle weakness (after taking steroids in the past)
- have recently visited a tropical country
- are
suffering from ulcerative colitis (chronic inflammatory bowel disease),
epilepsy (seizure), thrombophlebitis (swelling and redness along a
vein), exanthematous disease (disease affecting the skin) - have
metastatic carcinoma (cancer that has spread from one part of the body
to another), amoebic dysentery and strongyloidiasis (infestation of a
gut worm) - have/had diabetes, high blood pressure, glaucoma (eye condition), osteoporosis (thinning of bone)
- suffer from myasthenia gravies (type of muscle weakening problem), hypothyroidism (condition marked by low thyroid secretion)
- have/had any mental health problems
- have/had pheochromocytoma (adrenal gland tumour)
- high blood pressure
- are intolerant to certain sugars such as lactose
- are scheduled for a surgery (requiring anaesthesia)
Use in Paediatrics:
HISONE
5MG TABLET should be used with caution in children and adolescents
(aged below 18 years). Monitoring of heart function and structure is
advised if the medicine is to be administered to a premature baby.
Consult your doctor before taking HISONE 5MG TABLET.
Use in Geriatrics:
HISONE
5MG TABLET should be used with caution in elderly patients (aged above
65 years). Consult your doctor before taking HISONE 5MG TABLET.
INTERACTIONS
A. Drug – Drug interactions:
Before taking HISONE 5MG TABLET, inform your doctor if you are taking any of the following medicine:
- aspirin (used to reduce pain and relive pain)
- phenytoin, phenobarbital, carbamazepine, primidone (medicines used to manage epilepsy)
- ephedrine (used to manage manage low blood pressure during anaesthesia)
- rifabutin, rifampicin (medicines used to manage tuberculosis)
- warfarin (medicine used for blood thinning)
- diuretics (used to manage high blood pressure) Ex. chlorothiazide, chlorthalidone
- amphotericin, ketoconazole, itraconazole, pesaconazole, vericonazole (medicines used to manage fungal infections)
- aminoglutethimide (anticancer medicine)
- digoxin, furosemide, bumetanide (medicines used for heart failure)
- erythromycin, telithromycin, clarithromycin (medicines used to manage some infections)
- oral contraceptives (medicines used to manage pregnancy) Ex. ethinyl estradiol
- somatropin (used as a growth hormone)
- guanethidine, isosorbide mononitrate, isosorbide dinitrate, theophylline (medicines used for heart disease)
- sympathomimetics
(medicines used to manage asthma, low blood pressure, cough) Ex.
bambuterol, fenoterol, formoterol, ritodrine, salbutamol, salmeterol,
terbutaline - calcium supplements (Ex. Calcium carbonate, calcium citrate)
- NSAIDS (medicines used to reduce inflammation and relieve pain) Ex. ibuprofen, diclofenac, naproxen
- sodium phenylbutyrate (used for urea cycle disorder)
- medicine used in diabetes (Ex. insulin, metformin)
- ritonavir (used to manage HIV)
- methotrexate (medicine used to manage inflammatory conditions)
- cyclosporin (medicine used to manage transplant organ rejection)
- minoxidil, hydralazine (medicines used to reduce high blood pressure)
B. Drug – Food interaction:
Avoid drinking grapefruit juice while taking HISONE 5MG TABLET as it may interfere with the effect of the medicine.
Overdosage:
If
you or anyone else accidentally took more of HISONE 5MG TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of
overdosage are nausea/vomiting, salt & fluid retention, high blood
sugar and/or gastrointestinal bleeding.
SYNOPSIS
| Drug | : | Hydrocortisone |
| Pharmacological Category | : | Corticosteroid |
| Therapeutic Indication | : | Replacement therapy (to replace insufficient adrenal Hormone), Inhibits adrenocorticotropic hormone, Few types of illness and replace insufficient adrenal hormone (after injury, surgery and/or other stressful events) |
|
Dosage Forms |
: | Cream, Foam, Enema, Tablet, Injection |
| Weight | 17.5 g |
|---|
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