HYQ 400mg Tablet 10’S

HYQ 400mg Tablet 10’S

155.00

INTRODUCTION ABOUT HYQ 300 TABLET

HYQ
300 TABLET contains Hydroxychloroquine which belongs to the group of
medicines called Antimalarials or Disease-Modifying Anti-Rheumatic Drugs
(DMARDs). It is used to manage malarial infection. Malaria is a
parasitic infection caused by the plasmodium parasite, which spreads in
blood by the bite of an infectious mosquito. It is characterized by
symptoms such as fever, chills, sweating, headache, nausea, vomiting,
body pain and general discomfort. It is also used to manage rheumatoid
arthritis, discoid and systemic lupus erythematosus in adults and
manages juvenile idiopathic arthritis in children. Also, it is used to
manage skin problems (which are sensitive to sunlight). It is used in
patients with type 2 diabetes mellitus as an adjunct to diet and
exercise to improve glycemic control of patients on metformin and
sulfonylurea combination.

Rheumatoid arthritis, discoid and
systemic lupus erythematosus is an inflammatory autoimmune condition in
which the immune system attacks its own body cells. It is generalized by
symptoms such as painful swelling, stiffness, swelling, tenderness or
weakness of bone joints, weakness, fever, skin rashes and anemia. HYQ
300 TABLET is not recommended for use in patients with maculopathy or
retinal disorder of the eye and changes in eye color, etc. Your doctor
may recommend you to take relevant tests to understand your existing
condition.

Before taking HYQ 300 TABLET inform your doctor if you
have heart disease, psoriasis or porphyria, blood disorders (such as
aplastic anemia, agranulocytosis, leukopenia or thrombocytopenia)
glucose-6-phosphate dehydrogenase (G6PD) deficiency, psychological
disorders, abnormal blood sugar levels. HYQ 300 TABLET should be used
with caution in pregnant and breastfeeding women only if advised by the
doctor. HYQ 300 TABLET should be used with caution in children and
elderly patients (aged 65 years and above). The most common side effects
of taking HYQ 300 TABLET are nausea, vomiting, loose stools, stomach
pain, headache, loss of appetite and skin rashes. Consult your doctor if
any of the side effects worsen.

HYQ 400mg Tablet 10'S

155.00

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USES OF HYQ 300 TABLET

  • Manages malarial infection in adults and children
  • Manage rheumatoid arthritis, discoid and systemic lupus erythematosus
  • Manage skin problems (which are sensitive to sunlight)
  • Manage juvenile idiopathic arthritis
  • Used in patients with type 2 diabetes mellitus to improve glycemic control

HOW HYQ 300 TABLET WORKS

HYQ
300 TABLET works by increasing the potential of Hydrogen (pH) in a cell
which disrupts the survival of infectious organisms and it also
decreases the release of inflammatory enzymes. As a result, HYQ 300
TABLET manages malarial infections in children and adults, it also
manages rheumatoid arthritis and lupus erythematosus in adults.

DIRECTIONS FOR USE

Always
take HYQ 300 TABLET as directed by your physician. Swallow the medicine
as a whole with a glass of water and do not crush or chew the medicine.
Your doctor will decide the correct dose, duration and frequency for
you depending upon your age, body weight and disease conditions.

SIDE EFFECTS OF HYQ 300 TABLET

COMMON

  • Nausea
  • vomiting
  • Diarrhea
  • Stomach pain
  • Headache
  • Loss of appetite
  • Skin rashes or itching
  • Mood swings with uncontrollable laughing or crying

UNCOMMON

  • Changes in the color of the skin, nose, mouth or hair
  • Dizziness
  • Hair loss
  • Decreased reflexes
  • Vertigo (spinning sensation)
  • Ringing in the ears

Stop taking HYQ 300 TABLET and contact your doctor immediately if you experience any of the following side effects:

  • Severe
    allergic reactions (such as skin rash, redness, itching, swallowing or
    breathing problems, swelling of your lips, face, throat or tongue)
  • Blistering
    of the skin, particularly the mouth, face, nose and genitals, fever and
    flu-like symptoms such as eosinophilia and systemic symptoms (DRESS),
    stevens-johnson syndrome
  • Lowering of the blood glucose level
  • Muscle weakness, muscle spasms or cramps, or changes in sensation of your skin (tingling)
  • Eye problems (changes in color of the eye, blurring vision, sensitivity to light)
  • Weakening
    of the heart muscle, chest pain, an irregular or abnormal heartbeat,
    feeling dizzy or tired, swelling of feet, ankles and legs
  • Abnormal bleeding or bruising, tiredness and pale skin
  • Recurrent infection such as sore throat, mouth ulcers and fever
  • Muscle stiffness, abnormal movements or shivering of body parts
  • Altered behavior

HOW TO MANAGE SIDE EFFECTS

Loss Of Appetite

Eat
when you are hungry. Eat smaller meals more often than usual. Snack
only when you’re hungry. Eat a nutritious snack that is rich in calories
and protein, such as dried fruit and nuts. Consult your doctor
immediately if the symptoms worsen or persist.

Nausea And Vomiting

Stick
to simple meals while taking this medicine. Avoid eating oily rich,
fried or spicy foods. Do not lie down or sleep immediately after eating.
Consult your doctor if the symptom does not improve.        

Skin Rash Or Itching

Avoid
hot showers because hot water can irritate your skin further. Do not
scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. Consult your doctor if the symptom
worsens.

Stomach Pain

Try
to rest and relax. Eat and drink slowly or try to have smaller meals
more frequently. Keep a heat pad on your stomach. If the symptom does
not improve, consult your doctor.     

WARNING & PRECAUTIONS

PREGNANCY

Use with Caution

HYQ
300 TABLET should be used with caution in pregnant women if recommended
by your doctor. Inform your doctor immediately if you become pregnant
or think you may be pregnant while taking HYQ 300 TABLET.

BREASTFEEDING

Use with Caution

HYQ
300 TABLET should be used with caution in breastfeeding women only if
recommended by your doctor as it can pass through the breast milk.
Consult your doctor before taking HYQ 300 TABLET.

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate any machines if you experience blurred vision or any eye problems while taking HYQ 300 TABLET.

KIDNEY

Use with Caution

HYQ
300 TABLET should be taken with caution in patients with kidneys
problems. Consult your doctor before taking HYQ 300 TABLET.  

LIVER

Use with Caution

HYQ
300 TABLET should be taken with caution in patients with liver
problems. Consult your doctor for advice before taking HYQ 300 TABLET.

ALLERGY

Contraindicated

Do
not take HYQ 300 TABLET if you are allergic to Hydroxychloroquine,
similar medicines such as quinolones (Ex. chloroquine) and quinine or
any other ingredients of this medicine.

HEART DISEASE

Use with Caution

HYQ
300 TABLET should be taken with caution in patients with heart disease
(such as cardiomyopathy, abnormal heartbeat, long QT syndrome) or have a
history of heart attack. Consult your doctor before taking HYQ 300
TABLET.  

USE IN PEDIATRICS

Use with Caution

HYQ
300 TABLET should be used with caution in children. Your child’s doctor
will decide the dose, duration of management and its frequency
depending upon the child’s age, body weight, severities of disease and
other disease conditions. 

USE IN GERIATRICS

Use with Caution

HYQ
300 TABLET should be taken with caution in elderly patients (aged 65
years and above). Consult your doctor before taking HYQ 300 TABLET.  

OTHERS

HYQ 300 TABLET is not recommended for use if you:

  • Have an eye problem which affects the retina (maculopathy)
  • Experience change in eye color or any other problem

Before taking HYQ 300 TABLET, inform your physician if you:

  • Have abnormal blood sugar levels
  • Have glucose-6-phosphate dehydrogenase (G6PD) deficiency or porphyria
  • Have psoriasis
  • Have a blood disorder such as aplastic anemia, agranulocytosis, leukopenia or thrombocytopenia
  • Have any problems with nervous system or brain
  • Have serious stomach or gut problems
  • Have a psychological disorder such as mood swings or suicidal behaviors
  • Had a bad reaction to quinine in the past

INTERACTIONS

A. Drug-Drug interactions:

Before taking HYQ 300 TABLET, inform your doctor if you are taking any of the following medicines:

  • Insulin,
    sulfonylureas such as glimepiride, meglitinide, thiazolidinedione such
    as pioglitazone, metformin (used to manage diabetes)
  • Digoxin, amiodarone (used to manage heart disease)
  • Azithromycin,
    clarithromycin, erythromycin, gentamicin, neomycin, tobramycin and
     moxifloxacin (used to manage bacterial infections)
  • Cimetidine (used to manage stomach ulcers)
  • Neostigmine and pyridostigmine (used to manage myasthenia gravis and muscle weakness)
  • Tamoxifen (used to manage eye infections)
  • Halofantrine, mefloquine (used to manage malarial infection)
  • Amisulpride, quetiapine, risperidone (used to manage psychiatric disorders)
  • Rabies vaccine (used to manage rabies)
  • Ciclosporin (used to manage organ transplant rejection)
  • Praziquantel (used to manage worm infections)
  • Agalsidase (used to manage fabry’s disease)
  • Carbamazepine, sodium valproate, topiramate (used to manage fits or seizures)

Overdosage:

If
you or anyone else accidentally takes more of HYQ 300 TABLET, consult
your doctor immediately or visit a nearby hospital immediately if the
symptoms worsen. The symptoms may include abnormal or low blood
pressure, low potassium levels in the blood, abnormal heartbeat,
depression, seizures, impaired vision, transient blindness, cardiac
arrest, coma or death.

SYNOPSIS

Drug :   Hydroxychloroquine
Pharmacological Category :   Antimalarials or Disease Modifying Anti-Rheumatic Drugs
Therapeutic Indication :   To
manage malaria, rheumatoid arthritis, juvenile idiopathic arthritis,
discoid and systemic lupus erythematosus, skin problems                                                                    
Dosage Forms :   Tablet, Cream

MORE INFORMATION

STORAGE

  • Keep HYQ 300 TABLET out of reach of children
  • Store at room temperature

FAQs ABOUT HYQ 300 TABLET

Q: Can HYQ 300 TABLET be used during pregnancy?

A:
HYQ 300 TABLET should be used with caution in pregnant women only if
advised by the doctor. Consult your doctor for advice before taking HYQ
300 TABLET. Inform your doctor if you are planning or doubt if you are
pregnant.

Q: What are the common side effects of HYQ 300 TABLET?

A:
The most common side effects of taking HYQ 300 TABLET are nausea,
vomiting, loose stools, stomach pain, headache, loss of appetite and
skin rashes. Consult your doctor if any of the side effects worsen.   

Q: Is HYQ 300 TABLET safe for use in patients with diabetes?

A:
HYQ 300 TABLET should be used with caution in patients with diabetes.
Inform your doctor if you have diabetes and taking medicines to manage
the condition such as insulin, sulfonylureas such as glimepiride,
meglitinide, thiazolidinediones such as pioglitazone, metformin, etc.
HYQ 300 TABLET can lower the blood sugar levels. Consult your doctor if
the symptoms worsen or persist.

Q: Can I stop taking HYQ 300 TABLET if my symptoms of the disease subside?

A:
Though the symptoms of your disease subside, do not stop taking HYQ 300
TABLET unless recommended by your doctor as the disease and its
symptoms may worsen back again. Consult your doctor for advice.

Q: What happens when you forget to take HYQ 300 TABLET?

A:
If you forget to take a dose of HYQ 300 TABLET on time, take it as soon
as you remember. However, skip the missing dose if it’s time for the
next dose. Do not take a double dose to make up for a missed dose.

REFERENCES

1. KD. Tripathi. Anti-Rheumatoid and antigout drugs. Essentials of medical pharmacology. 8th edition. 2019. Page – 229.

2.
Armaan M Nazir, Bhavya Koganti, Kunal Gupta, Marrium S Memon, Muhammad
Bin Aslam Zahid, Vignarth Shantha Kumar, Mamatha Tappiti, and Jihan A
Mostafa. NIH National Library of Medicine, National center for
biotechnology information. Evaluating the Use of Hydroxychloroquine in
Treating Patients with Rheumatoid Arthritis. [Revised in Novemebr 2021]
[Accessed on 8th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575345/

3.
Bethesda (MD). NIH National Library of Medicine, National center for
biotechnology information. Hydroxychloroquine. [Revised in April 2021]
[Accessed on 8th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK548738/

4. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 8th July 2022] https://www.medicines.org.uk/emc/files/pil.1764.pdf

5.
Blackrock Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC).
[Revised in April 2022] [Accessed on 8th July
2022] https://www.medicines.org.uk/emc/files/pil.11732.pdf

6. Novitium Pharma LLC. NIH National Library of Medicine, DailyMed. [Revised in January 2022] [Accessed on 8th July 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=29dc13a8-b583-4a91-bf0d-6ef8b81bea62&type=display#section-9

7.
SPH Zhongxi Pharmaceutical Co. Hydroxychloroquine sulfate 100 mg
Tablets. [Revised in January 2022] [Accessed on 8th July 2022] https://en.idtaus.com.au/wp-content/uploads/2020/06/Patient-Information-Leaflet-Hydroxychloroquine-sulfate-20200602.pdf

USEFUL DIAGNOSTIC TESTS

  • Complete blood count
  • Liver function test

AUTHOR DETAILS

Written By Dr. Janet.C – Pharm.D
Reviewed By Dr. Sankara Babu Gorle – MBBS, MD(Pharmacology) View profile
Last updated on 31 Jul 2024 | 10:58 AM(IST)

Weight 17.5 g

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