INTRODUCTION ABOUT IMATIB A 100MG CAPSULE
IMATIB
A 100MG CAPSULE contains Imatinib which belongs to the group of
medicines called Tyrosine Kinase Inhibitors. It is used in adults,
children and adolescents to manage chronic myeloid leukaemia (CML) (a
form of leukaemia in which certain abnormal white cells (named myeloid
cells) start growing out of control) and philadelphia chromosome
positive acute lymphoblastic leukaemia (Ph-positive ALL) (a form of
leukaemia in which certain abnormal white cells (named lymphoblasts)
start growing out of control).
Also, it is used in adults only to
manage myelodysplastic/myeloproliferative diseases (MDS/MPD) (a group
of blood diseases in which some blood cells start growing out of
control), hyper eosinophilic syndrome (HES) and/or chronic eosinophilic
leukaemia (CEL) (a blood diseases in which some blood cells (named
eosinophils) start growing out of control), gastrointestinal stromal
tumours (GIST) (cancer of the stomach and bowels) and
dermatofibrosarcoma protuberans (DFSP) (cancer of the tissue beneath the
skin in which some cells start growing out of control).
Before
taking IMATIB A 100MG CAPSULE, inform your doctor if you have or ever
had kidney, liver or heart problems, hepatitis B infection and
thrombotic microangiopathy (symptoms include bruising, bleeding, fever,
fatigue and confusion).
IMATIB A 100MG CAPSULE is generally not
recommended for use in pregnant women unless advised by the doctor and
it is not recommended for use in breastfeeding women. IMATIB A 100MG
CAPSULE should be used with caution in children, adolescents and elderly
patients (aged 65 years and above).
The most common side effects
of taking IMATIB A 100MG CAPSULE are nausea, vomiting, diarrhea,
headache, weight gain, loss of appetite, disturbed sense of taste,
blurred vision and weakness. Consult your physician if any of the side
effects worsen.
USES OF IMATIB A 100MG CAPSULE
Manage adults, children and adolescents for:
- chronic myeloid leukaemia (CML)
- philadelphia chromosome positive acute lymphoblastic leukaemia (Ph-positive ALL)
Manage adults for:
- myelodysplastic/myeloproliferative diseases (MDS/MPD)
- hyper-eosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia (CEL)
- gastrointestinal stromal tumors (GIST)
- dermatofibrosarcoma protuberans (DFSP)
HOW IMATIB A 100MG CAPSULE WORKS
IMATIB
A 100MG CAPSULE is a protein-tyrosine kinase inhibitor. Tyrosine
kinases are proteins which act as chemical messengers that are used by
the cancer cells to signal each other for their growth, therefore this
medicine works by blocking the enzyme which stops the cancer cells from
growing.
DIRECTIONS FOR USE
Take
IMATIB A 100MG CAPSULE as advised by your physician. Swallow the IMATIB
A 100MG CAPSULE with a glass of water. Do not crush or chew the
medicine. Your doctor will decide the correct dose and duration for you
depending upon your age, body weight and disease condition.
SIDE EFFECTS OF IMATIB A 100MG CAPSULE
COMMON
- headache or feeling tired
- nausea, vomiting, diarrhea or indigestion
- rash
- muscle cramps, joint, muscle or bone pain
- swelling such as round ankles or puffy eyes
- weight gain
- loss of appetite, weight loss or disturbed sense of taste
- feeling dizzy or weak
- insomnia
- conjunctivitis watery eyes, or blurred vision
- nose bleeds
- pain or swelling in the abdomen, flatulence, heartburn or constipation
- itching
- unusual hair loss or thinning
- numbness of the hands or feet
- mouth ulcers
- dry mouth, dry skin or dry eye
- decreased or increased skin sensitivity
- hot flushes, chills or night sweats
RARE
Stop taking IMATIB A 100MG CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- rapid weight gain, severe fluid retention
- infection symptoms such as fever, severe chills, sore throat or mouth ulcers, low white blood cells
- unexpected bleeding or bruising
- sign of heart problems like chest pain or irregular heart rhythm
- sign of lung problems like cough, difficulty in breathing or painful breathing
- signs of low blood pressure like feeling light-headed, dizzy or fainting
- sign of liver problems like nausea, loss of appetite, dark-colored urine, yellow skin or eyes
- sign
of skin problems like rash, red skin with blisters on the lips, eyes,
skin or mouth, peeling skin, fever, raised red or purple skin patches,
itching, burning sensation, a pustular eruption and sudden swelling and
redness of the skin (cellulitis) - sign of gastrointestinal disorders like severe abdominal pain, blood in vomit, stools or urine, black stools
- signs of kidney problems like severely decreased urine output and feeling thirsty
- signs of bowel problems like nausea with diarrhea and vomiting, abdominal pain or fever
- signs
of nervous system problems like severe headache, weakness or paralysis
of limbs or face, difficulty speaking, sudden loss of consciousness,
bleeding or swelling in skull/brain - signs of low levels of red blood cells like pale skin, feeling tired and breathlessness and having dark urine
- signs of raynaud’s syndrome like numb or cold toes and fingers
- signs of muscle problems like muscle spasms with a fever, red-brown urine, pain or weakness in your muscles
- eye pain or deterioration in vision, bleeding in the eyes
- pain in hips or difficulty walking
- difficulty in hearing
- signs of problems with ovaries or womb like pelvic pain with unexpected vaginal bleeding
- thrombotic microangiopathy (blood clots in small blood vessels)
HOW TO MANAGE SIDE EFFECTS
Nausea or vomiting:
Try
to take IMATIB A 100MG CAPSULE with or just after a meal or a snack.
Stick to simple meals. Avoid eating oil rich, fried or spicy foods.
Consult your doctor if the symptom does not improve.
Diarrhoea:
Drink
lot of fluids such as water or fruit juices to keep yourself hydrated.
Avoid taking any medicine on your own for managing diarrhea. Consult
your doctor if the symptom does not improve.
Headache:
Rest
and relax. Drink plenty of fluids such as water or electrolytes. Apply a
pain-relieving balm on the forehead if required. Do not consume too
much of alcohol. Consult your doctor if the symptom does not improve.
Dry mouth:
Sip
water regularly and other sugar free liquids. Do not use mouthwashes
that contain alcohol because they can make your mouth dry, use mouthwash
that is used only for dry mouth. Limit your caffeine intake. Avoid
smoking or using tobacco products. Consult your doctor if the symptom
does not improve.
Tiredness:
Drink plenty
of fluid and eat balanced diet and frequent meals. Do regular minimal
exercise and follow regular sleep schedule. Consult your doctor if the
symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
IMATIB
A 100MG CAPSULE is generally not recommended for use in pregnant women
unless considered clearly necessary. Women who might become pregnant are
advised to use effective contraceptive measures during management and
for 15 days after ending the> management. Consult your doctor before
taking IMATIB A 100MG CAPSULE.
BREASTFEEDING
IMATIB
A 100MG CAPSULE is not recommended for use during breastfeeding and for
15 days after ending the management as it may harm the baby. Consult
your doctor before taking IMATIB A 100MG CAPSULE.
DRIVING AND USING MACHINES
Do
not drive or operate any machines if you experience dizziness,
drowsiness or blurred vision after taking IMATIB A 100MG CAPSULE.
KIDNEY
IMATIB
A 100MG CAPSULE should be used with caution in patients with kidney
problem. Consult your doctor before taking IMATIB A 100MG CAPSULE.
LIVER
IMATIB
A 100MG CAPSULE should be used with caution in patients with liver
problems and hepatitis B infection. Consult your doctor before taking
IMATIB A 100MG CAPSULE.
ALLERGY
Do not take IMATIB A 100MG CAPSULE if you are allergic to imatinib or any other ingredients of this medicine.
HEART DISEASE
IMATIB
A 100MG CAPSULE should be used with caution in patients with heart
problem. Consult your doctor before taking IMATIB A 100MG CAPSULE.
OTHERS
Before taking IMATIB A 100MG CAPSULE, inform your doctor if you have:
- thrombotic microangiopathy symptoms such as bruising, bleeding, fever, fatigue and confusion
Use in pediatrics:
IMATIB A 100MG CAPSULE should be used with caution in children and adolescents. Consult your child’s doctor for advice.
Use in geriatrics:
IMATIB
A 100MG CAPSULE should be used with caution in elderly patients (aged
65 years and above). Consult your doctor before taking IMATIB A 100MG
CAPSULE.
INTERACTIONS
A. Drug-Drug interactions:
Before taking IMATIB A 100MG CAPSULE, inform your doctor if you are taking any of the following medicines:Â
- medicines used to manage fever and pain (Ex. paracetamol)
- st. john’s wort (used to manage depression)
- medicines used to manage blood clots (Ex. clopidogrel)
- medicine used to manage thyroid (levothyroxine)
Overdosage:
If
you or anyone else accidentally take too much of IMATIB A 100MG
CAPSULE, consult your doctor immediately or visit the nearby hospital.
| Weight | 17.5 g |
|---|
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