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NEVIR ER Tablet 30’s
Original price was: ₹668.00.₹599.00Current price is: ₹599.00.
*30 Tablet(s) in a Strip
* Mkt: Emcure Pharmaceuticals Ltd
* Country of Origin: India
* Delivery charges if applicable will be applied at checkout
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INTRODUCTION ABOUT NEVIR ER TABLET
NEVIR
ER TABLET contains Nevirapine which belongs to the group of medicines
called Antiretroviral drugs. It indicated for the management of Human
Immunodeficiency Virus (HIV) infection in combination with other
anti-retroviral medicines in adults, adolescents and children.
HIV
is a virus which severely damages the immune system and leads to
Acquired Immune Deficiency Syndrome (AIDS) which is characterized by
fever, chills, rash, night sweat, muscle aches, sore throat, fatigue.
During management, your doctor will advise you to take certain blood
tests to monitor your liver function.
NEVIR ER TABLET should be
used with caution in patients having inflammation of liver (hepatitis B
or C) or abnormal liver function tests. Before taking NEVIR ER TABLET,
inform your doctor if are undergoing kidney dialysis or have any heart
disease. NEVIR ER TABLET should be used with caution in pregnant woman
and is not intended for use in breastfeeding women.
Your doctor
will prescribe the right dose of NEVIR ER TABLET for your child
depending on their age, body weight and body surface area. The most
common side effects of taking NEVIR ER TABLET are skin rash, headache,
fatigue (feeling tired), nausea, vomiting, abdominal pain, diarrhea, fever, etc.
USES OF NEVIR ER TABLET
- Used
in adults, adolescents and children to manage Human Immunodeficiency
Virus (HIV) infection in combination with other anti-retroviral
medicines
HOW NEVIR ER TABLET WORKS
NEVIR
ER TABLET helps control HIV-1 infection by stopping reverse
transcriptase (an enzyme needed by HIV in order to multiply) from
working.
DIRECTIONS FOR USE
Take
NEVIR ER TABLET as advised by your physician. Swallow with a glass of
water, do not crush or chew it. Your doctor will decide the correct dose
and duration for you depending upon your age, body weight and disease
condition. Do not stop taking NEVIR ER TABLET unless your doctor advises
you to stop.
SIDE EFFECTS OF NEVIR ER TABLET
COMMON
- skin rash
- decreased numbers of white blood cells which makes you more prone to infection
- headache, fatigue (feeling tired)
- nausea, vomiting, stomach pain, diarrhoea
- signs of inflammation of the liver (hepatitis) like jaundice, nausea, dark urine, light coloured stools, abdominal pain
- fever
UNCOMMON
- angioedema (fluid retention under the skin), hives
- anaemia (decreased red blood cells count)
- joint or muscle pain
- high blood pressure
RARE
- signs
of sudden and intense inflammation of the liver or fulminant hepatitis
like swollen belly, upper right abdomen pain, vomiting, etc - drug reaction with systemic symptoms (drug reaction with increased eosinophil count or eosinophilia)
Stop taking NEVIR ER TABLET and contact your doctor immediately if you experience any of the following side effects:
- symptoms of infection
- muscle
weakness, weakness beginning in the hands and feet and moving upwards
the trunk of the body, throbbing sensation, shakiness or hyperactivity - changes in body fat
- osteonecrosis
(a bone disorder causing joint stiffness, aches and pains especially of
the hip, knee and shoulder and difficulty in movement) - rash
that appears as blistering skin reaction, which can be severe or
life-threatening (Ex. toxic epidermal necrolysis, Stevens-Johnson
syndrome) - symptoms of severe allergic or anaphylactic reaction
like rash, swelling of face, breathing difficulty, anaphylactic shock,
fever, skin blisters, mouth sores, eye inflammation, muscle or joint
pain, feeling unwell, liver or kidney failure - liver damage (loss of appetite, nausea, vomiting, yellow skin, abdominal pain)
HOW TO MANAGE SIDE EFFECTS
Diarrhoea:
To
avoid dehydration in your body, drink plenty of fluids such as water,
fruit juices or electrolytes. If symptom persists, contact your doctor.
Muscle pain:
Rest
and elevate the painful area. Place ice packs to reduce inflammation
and heat to improve blood flow. Taking a warm shower may help in
relaxation. Take pain killer medicines after consulting your doctor. If
symptom persists, contact your doctor.
Nausea or vomiting:
Take
NEVIR ER TABLET with or just after meals. Stick to simple meals. Avoid
eating oil rich or spicy foods. If symptom persists, contact your
doctor.
Headache:
Apply hot or cold-water
bag on your head. Try to take rest in a quiet and dark room. Drink tea
or coffee. Massage the scalp or head with mild pressure. If symptom
persists, contact your doctor.
Skin rash:
Try
to avoid hot showers because it may cause skin irritation. Avoid
frequent contact and rubbing over the affected area. Use sunscreen and
protective clothing when outdoors. If symptom persists, contact your
doctor.
WARNING & PRECAUTIONS
PREGNANCY
NEVIR
ER TABLET should be used with caution in woman who are pregnant or
planning to become pregnant. Women should use effective contraception
methods during management with NEVIR ER TABLET. Consult your doctor
before taking it.
BREASTFEEDING
NEVIR
ER TABLET is not recommended for use in breastfeeding women as your
baby may become infected with HIV through breastmilk. Consult your
doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel extremely tired after taking NEVIR ER TABLET.
ALCOHOL
Avoid consumption of alcohol while taking NEVIR ER TABLET as it may increase the risk of bone problems.
KIDNEY
NEVIR ER TABLET should be taken with caution in patients undergoing kidney dialysis. Consult your doctor before taking it.
LIVER
NEVIR
ER TABLET should be used with caution in patients having inflammation
of liver (hepatitis B or C) or abnormal liver function tests. Consult
your doctor before taking it.
ALLERGY
Do not take NEVIR ER TABLET if you are allergic to Nevirapine or any of the other ingredients of this medicine.
HEART DISEASE
NEVIR ER TABLET should be taken with caution in patients having heart disease. Consult your doctor before taking it.
OTHERS
NEVIR ER TABLET is not recommended for use if you:
- have previously discontinued management with nevirapine due to severe skin rashes or liver problems
Use in Pediatrics:
Your
doctor will prescribe the right dose of NEVIR ER TABLET for your child
depending on their age, body weight and body surface area. Consult your
child’s doctor for advice.
Use in Geriatrics:
NEVIR ER TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking it.
INTERACTIONS
A. Drug – Drug interactions:
Before taking NEVIR ER TABLET, inform your doctor if you are taking any of the following medicines:
- St. John’s Wort (herbal medicine used for depression)
- rifampicin, rifabutin (used to manage tuberculosis)
- clarithromycin (used to manage bacterial infections)
- fluconazole, ketoconazole, itraconazole (medicines used to manage fungal infections)
- methadone (medicine used in management of opiate addicts)
- warfarin (used to reduce clotting of blood)
- medicines used to manage pregnancy (Ex. ethinyl estradiol, progestin)
- atazanavir,
lopinavir, ritonavir, fosamprenavir, efavirenz, etravirine, zidovudine,
elvitegravir, cobicistat, rilpivirine (other medicines used to manage
HIV-infection)
Overdosage:
If you
or anyone else accidentally take too much of NEVIR ER TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of NEVIR
ER TABLET overdose include swelling, redness, tiredness, fever,
headache, sleep problems, nausea, rash, spinning sensation, vomiting and
weight loss.
SYNOPSIS
| Drug | :Â Â | Nevirapine |
| Pharmacological Category | :  | Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) |
| Therapeutic Indication | :Â Â | HIV infection |
| Dosage Forms | :Â Â | Tablet, Oral suspension, Suspension |
MORE INFORMATION
- Keep NEVIR ER TABLET out of reach of children
- Store at room temperature
FAQs ABOUT NEVIR ER TABLET
Can I stop taking NEVIR ER TABLET if I feel better?
Do
not stop taking NEVIR ER TABLET unless your doctor advises you to stop.
Taking all doses at the appropriate times increases the effectiveness
of your medicine and reduces the chances of you developing resistance to
your antiretroviral medicine. If you stop taking NEVIR ER TABLET for
more than 7 days, your doctor will advise you to start the 14 day
‘lead-in’ period once again, before returning to the usual dose.
What should I do if I forget to take a dose of NEVIR ER TABLET?
If
you forget a dose of NEVIR ER TABLET, take it as soon as you remember.
If you notice that you have missed a dose within 8 hours of when it was
due, take it as soon as possible. If it has been more than 8 hours since
the dose was due, then take the next dose at the usual time. Do not
take NEVIR ER TABLET two times to make up for the forgotten dose.
Does NEVIR ER TABLET manage HIV infection?
NEVIR
ER TABLET does not completely manage HIV infection; it reduces the
amount of virus in your body and keeps a check at it. Therefore, you may
continue to develop infections and other illnesses associated with HIV
infection and thus, you should remain in regular contact with your
doctor.
Can I get other infections while on management with NEVIR ER TABLET?
In
some patients with AIDS and a history of opportunistic infection, signs
and symptoms of inflammation from previous infections may occur soon
after NEVIR ER TABLET management is started. It is assumed that these
symptoms are due to an improvement in the body’s immune response,
enabling the body to fight infections that may have been present with no
obvious symptoms. If you notice any symptoms of infection while taking
NEVIR ER TABLET, please inform your doctor immediately.
REFERENCES
1. KD. Tripathi. Antiretroviral drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page –864.
2.
J-J Parienti , R Verdon. Nevirapine and cardiovascular risk. National
Library of Medicine, National center for biotechnology information.
PubMed.gov. September 2010. [Accessed 9th December 2022].https://pubmed.ncbi.nlm.nih.gov/20434285/
3.
Ena J, Amador C, Benito C, Pasquau F. Pharmacological and clinical
evidence of nevirapine immediate- and extended-release formulations. NIH
National Library of Medicine, National Centre for biotechnology
information. Pubmed Central. November 2012. [Accessed 9th December
2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501953/
4.
APL Swift Services (Malta) Limited. Electronic Medicines Compendium
(EMC). [Revised in May 2022] [Accessed 9th December 2022]. https://www.medicines.org.uk/emc/files/pil.7063.pdf
5. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed 9th December 2022]. https://www.medicines.org.uk/emc/files/pil.8888.pdf
6. Boehringer Ingelheim Pharmaceuticals, Inc. Viramune (Nevirapine). [Revised in June 2022] [Accessed 9th December 2022]. https://content.boehringer-ingelheim.com/DAM/4e167be8-c829-4ca6-ba08-af1e01215de4/viramune-us-pi.pdf
| Weight | 45 g |
|---|
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